Doxazosin, sold under the brand names Cardura among others, is a medication used to treat symptoms of benign prostatic hyperplasia (enlarged prostate) and hypertension (high blood pressure).[1][2] For high blood pressure, it is a less preferred option.[2] It is taken by mouth.[2]
Common side effects include dizziness, sleepiness, swelling, nausea, shortness of breath, and abdominal pain.[2] Severe side effects may include low blood pressure with standing, an irregular heart beat, and priapism.[2][3] It is a α1-selective adrenergic blocker in the quinazoline class of compounds.[2]
Doxazosin was patented in 1977 and came into medical use in 1988.[4] It is available as a generic medication.[3] In 2021, it was the 195th most commonly prescribed medication in the United States, with more than 2million prescriptions.[5][6]
A 2021 study associated doxazosin with decelerated biological aging in humans and confirmed its causal role in longevity in C. elegans.[7]
^ ab"Cardura- doxazosin mesylate tablet". DailyMed. Retrieved 18 June 2021.
^ abcdef"Doxazosin Mesylate Monograph for Professionals". Drugs.com. American Society of Health-System Pharmacists. Retrieved 17 March 2019.
^ abBritish national formulary : BNF 76 (76 ed.). Pharmaceutical Press. 2018. p. 765. ISBN 9780857113382.
^Fischer J, Ganellin CR (2006). Analogue-based Drug Discovery. John Wiley & Sons. p. 455. ISBN 9783527607495.
^"The Top 300 of 2021". ClinCalc. Archived from the original on 15 January 2024. Retrieved 14 January 2024.
^"Doxazosin - Drug Usage Statistics". ClinCalc. Retrieved 14 January 2024.
^McIntyre RL, Rahman M, Vanapalli SA, Houtkooper RH, Janssens GE (2021). "Biological Age Prediction From Wearable Device Movement Data Identifies Nutritional and Pharmacological Interventions for Healthy Aging". Frontiers in Aging. 2: 708680. doi:10.3389/fragi.2021.708680. PMC 9261299. PMID 35822021.
Doxazosin, sold under the brand names Cardura among others, is a medication used to treat symptoms of benign prostatic hyperplasia (enlarged prostate)...
medications have proven effective in treating chronic epididymitis, including doxazosin. Epididymitis makes up 1 in 144 visits for medical care (0.69 percent)...
are the most common choice for initial therapy. They include alfuzosin, doxazosin, silodosin, tamsulosin, terazosin, and naftopidil. They have a small to...
alprostadil). Other medication groups reported are antihypertensives (e.g. Doxazosin), antipsychotics (e.g., chlorpromazine, clozapine), antidepressants (most...
(ALLHAT showed that doxazosin, an alpha-adrenergic receptor blocker, had a higher incidence of heart failure events, and the doxazosin arm of the study was...
while taking tamsulosin. Alpha blockers, including prazosin, terazosin, doxazosin, or tamsulosin, do not appear to affect all-cause mortality in heart failure...
which have been successfully used for this condition are medications doxazosin, carvedilol, captopril, and propranolol hydrochloride. Treatment of coexisting...
restore the normal blood pressure. Antagonists of alpha-1 receptors (doxazosin, prazosin) cause vasodilation (a decrease in vascular smooth muscle tone...
hydrochlorothiazide) Synergistic effects with other antihypertensives (e.g. doxazosin) Sucralfate Potentially hazardous interactions with other drugs: Analgesics:...
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