Drug that opposes downstream effects of postganglionic nerve firing in sympathetic nervous system
A sympatholytic (sympathoplegic) drug is a medication that opposes the downstream effects of postganglionic nerve firing in effector organs innervated by the sympathetic nervous system (SNS).[1] They are indicated for various functions; for example, they may be used as antihypertensives. They are also used to treat anxiety, such as generalized anxiety disorder, panic disorder and PTSD. In some cases, such as with guanfacine, they have also shown to be beneficial in the treatment of ADHD.
A sympatholytic (sympathoplegic) drug is a medication that opposes the downstream effects of postganglionic nerve firing in effector organs innervated...
which mimics the action of sympathetic nervous system activation; and sympatholytic drugs which reduce or interrupt the action of sympathetic nervous system...
Urapidil is a sympatholytic antihypertensive drug. It acts as an α1-adrenoceptor antagonist and as an 5-HT1A receptor agonist. Although an initial report...
effects of norepinephrine released by the sympathetic nervous system; sympatholytic drugs, in contrast, block at least some of the effects. Both of these...
blocker. Today, it is used therapeutically in some countries due to its sympatholytic, anti-inflammatory, perfusion-enhancing, and mood-enhancing effects...
schizophrenia or bipolar I or II disorder. Similar to clonidine, it is a sympatholytic drug that acts as an agonist of α2-adrenergic receptors in certain parts...
found in Ephedra species) Adrenergic storm Sympathetic nervous system Sympatholytic Ellie Kirov (9 November 2021). Herlihy's the Human Body in Health and...
main action as a slowing of the rising phase of the action potential. Sympatholytic drugs (drugs blocking the effects of the sympathetic nervous system):...
vertigo, and weight gain) α1- and α2-adrenergic receptors (accounting for sympatholytic properties, lowering of blood pressure, reflex tachycardia, vertigo...
such as reserpine, tetrabenazine, and deserpidine, which are used as sympatholytics or antihypertensives, and in the past as antipsychotics. Dopamine releasing...
Bethanidine (or betanidine) is a sympatholytic drug. Phenoxybenzamine Prichard BN, Johnston AW, Hill ID, Rosenheim ML (January 1968). "Bethanidine, Guanethidine...
PMC 10324265. PMID 37415177. Defronzo RA (April 2011). "Bromocriptine: a sympatholytic, d2-dopamine agonist for the treatment of type 2 diabetes". Diabetes...
Union of Basic and Clinical Pharmacology. Retrieved 3 June 2016. This sympatholytic drug is used in the treatment of hypertension, anxiety and post-traumatic...
ulceration or large artery thrombotic events may be prescribed aspirin. Sympatholytic agents, such as the alpha-adrenergic blocker prazosin, may provide temporary...
"Pharmacology and clinical use of moxonidine, a new centrally acting sympatholytic antihypertensive agent". Journal of Human Hypertension. 11 (Suppl 1):...
propranolol) Propranolol is classified as a competitive non-cardioselective sympatholytic beta blocker that crosses the blood–brain barrier. It is lipid soluble...
nuclear materials Tenex, a brand name for the medication guanfacine, a sympatholytic used to treat hypertension, ADHD and anxiety Tenex, a brand name for...
Helminen A, Karhuvaara S (September 1998). "Reversal of the sedative and sympatholytic effects of dexmedetomidine with a specific alpha2-adrenoceptor antagonist...
receptors in the vasomotor center in the brainstem. This binding has a sympatholytic effect, suppresses release of norepinephrine, ATP, renin, and neuropeptide...
camsilate (INN) or trimethaphan camsylate (USAN), trade name Arfonad, is a sympatholytic drug used in rare circumstances to lower blood pressure. Trimetaphan...
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