The ciliary neurotrophic factor receptor, also known as CNTFR, binds the ciliary neurotrophic factor. This receptor and its cognate ligand support the survival of neurons.[1] This receptor is most closely related to the interleukin-6 receptor. This receptor possesses an unusual attachment to the cell membrane through a glycophosphatidylinositol linkage.[2]
^Davis S, Aldrich TH, Valenzuela DM, Wong VV, Furth ME, Squinto SP, Yancopoulos GD (1991). "The receptor for ciliary neurotrophic factor". Science. 253 (5015): 59–63. Bibcode:1991Sci...253...59D. doi:10.1126/science.1648265. PMID 1648265.
^Sleeman MW, Anderson KD, Lambert PD, Yancopoulos GD, Wiegand SJ (2000). "The ciliary neurotrophic factor and its receptor, CNTFR alpha". Pharm Acta Helv. 74 (2–3): 265–72. doi:10.1016/S0031-6865(99)00050-3. PMID 10812968.
and 26 Related for: Ciliary neurotrophic factor receptor information
Ciliaryneurotrophicfactor is a protein that in humans is encoded by the CNTF gene. The protein encoded by this gene is a polypeptide hormone and neurotrophic...
other systems, including the ciliaryneurotrophicfactor, growth hormone and prolactin. Leukemia inhibitory factorreceptor has been shown to interact with...
McLaurin DL, Anderson KJ, Lee N (1999). "Regulation of ciliaryneurotrophicfactorreceptor alpha in sciatic motor neurons following axotomy". Neuroscience...
complex with cardiotrophin-like cytokine factor 1 and acts on cells expressing ciliaryneurotrophicfactorreceptors. The complex can promote survival of...
to these four neurotrophins, the GDNF family of ligands, and ciliaryneurotrophicfactor (CNTF), among other biomolecules. Neurotrophin-6 and neurotrophin-7...
cytokine/cytokine-like factor-1 composite cytokine: specific requirement of the membrane-bound form of ciliaryneurotrophicfactorreceptor alpha component"...
Hepatocyte growth factorreceptor (HGF receptor) is a protein that in humans is encoded by the MET gene. The protein possesses tyrosine kinase activity...
IL-27Rα subunits. EBI3 is a homologue to IL-12 p40 and to the ciliaryneurotrophicfactorreceptor, whose expression is induced in B lymphoblastoid cells by...
also been shown to increase astrocyte proliferation in vitro. Ciliaryneurotrophicfactor (CNTF) is a cytosolic protein that is not secreted. CNTF has...
2003). "Signaling of human ciliaryneurotrophicfactor (CNTF) revisited. The interleukin-6 receptor can serve as an alpha-receptor for CTNF". The Journal...
enhancer of the human ciliaryneurotrophicfactorreceptor (CNTFRalpha) gene by the TR4 orphan receptor. A member of steroid receptor superfamily". The Journal...
Fibroblast growth factorreceptor 2 (FGFR2) also known as CD332 (cluster of differentiation 332) is a protein that in humans is encoded by the FGFR2 gene...
receptor family. This particular receptor is very similar to ciliaryneurotrophicfactor, since both contain an extracellular region with a 2-domain structure...
Glial cell line-derived neurotrophicfactor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophicfactors that play key roles in...
derived neurotrophicfactor (GDNF), and ciliaryneurotrophicfactor (CNTF) was presented to Dorsal root ganglion cultures in vitro. One factor from each...
pathways. CNTF: Ciliaryneurotrophicfactor is another protein that acts as a survival factor for motor neurons. CNTF acts via a receptor complex that includes...
gene is a secreted glycoprotein, which is a member of the hematopoietin receptor family related to the p40 subunit of interleukin 12 (IL-12). It plays a...
hippocampal brain‐derived neurotrophicfactor (BDNF). Due to the relationship between the presence of BDNF and ciliaryneurotrophicfactor and the preservation...
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