CRLF1 information

CRLF1
Identifiers
Aliases	CRLF1, CISS, CISS1, CLF, CLF-1, NR6, zcytor5, cytokine receptor like factor 1
External IDs	OMIM: 604237 MGI: 1340030 HomoloGene: 3489 GeneCards: CRLF1
Gene location (Human)
Chr.	Chromosome 19 (human)
End	18,607,741 bp
Gene location (Mouse)
Chr.	Chromosome 8 (mouse)
End	70,956,731 bp
RNA expression pattern
	Top expressed in
	right coronary artery; ; popliteal artery; ; left coronary artery; ; thoracic aorta; ; ascending aorta; ; right lobe of thyroid gland; ; left lobe of thyroid gland; ; nucleus accumbens; ; tibial nerve; ; Brodmann area 9;
	Top expressed in
	seminiferous tubule; ; corneal stroma; ; maxillary prominence; ; lower lip; ; submandibular gland; ; upper lip; ; hand; ; calvaria; ; spermatid; ; molar;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein heterodimerization activity; ciliary neurotrophic factor receptor binding; cytokine activity; protein binding; cytokine binding; cytokine receptor activity;
Cellular component	extracellular region; CRLF-CLCF1 complex; extracellular space; cytosol; external side of plasma membrane; receptor complex;
Biological process	negative regulation of neuron apoptotic process; ureteric bud development; positive regulation of cell population proliferation; negative regulation of motor neuron apoptotic process; positive regulation of tyrosine phosphorylation of STAT protein; regulation of signaling receptor activity; cytokine-mediated signaling pathway; interleukin-27-mediated signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	9244
	12931
	ENSG00000006016
	ENSMUSG00000007888
	O75462
	Q9JM58
	NM_004750
NM_018827; NM_001378799; NM_001378800; NM_001378801; NM_001378802;
	NM_001378803
	NP_004741
NP_061297; NP_001365728; NP_001365729; NP_001365730; NP_001365731;
	NP_001365732
	Wikidata
View/Edit Human	View/Edit Mouse

Cytokine receptor-like factor 1 is a protein that in humans is encoded by the CRLF1 gene.^[5]^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000006016 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000007888 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Elson GC, Graber P, Losberger C, Herren S, Gretener D, Menoud LN, Wells TN, Kosco-Vilbois MH, Gauchat JF (Aug 1998). "Cytokine-like factor-1, a novel soluble protein, shares homology with members of the cytokine type I receptor family". J Immunol. 161 (3): 1371–9. doi:10.4049/jimmunol.161.3.1371. PMID 9686600.
^ "Entrez Gene: CRLF1 cytokine receptor-like factor 1".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000006016 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000007888 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid9686600-5] Elson GC, Graber P, Losberger C, Herren S, Gretener D, Menoud LN, Wells TN, Kosco-Vilbois MH, Gauchat JF (Aug 1998). "Cytokine-like factor-1, a novel soluble protein, shares homology with members of the cytokine type I receptor family". J Immunol. 161 (3): 1371–9. doi:10.4049/jimmunol.161.3.1371. PMID 9686600.

[entrez-6] "Entrez Gene: CRLF1 cytokine receptor-like factor 1".

CRLF1 information

and 4 Related for: CRLF1 information

CRLF1

Fibronectin type III domain

CLCF1

List of OMIM disorder codes