positive regulation of isotype switching to IgE isotypes
receptor signaling pathway via JAK-STAT
positive regulation of astrocyte differentiation
positive regulation of immunoglobulin production
cell surface receptor signaling pathway
positive regulation of B cell proliferation
positive regulation of cell population proliferation
B cell differentiation
positive regulation of tyrosine phosphorylation of STAT protein
regulation of signaling receptor activity
cytokine-mediated signaling pathway
Sources:Amigo / QuickGO
Orthologs
Species
Human
Mouse
Entrez
23529
56708
Ensembl
ENSG00000175505
ENSMUSG00000040663
UniProt
Q9UBD9
Q9QZM3
RefSeq (mRNA)
NM_013246 NM_001166212
NM_019952 NM_001310038 NM_001310039
RefSeq (protein)
NP_001159684 NP_037378
NP_001296967 NP_001296968 NP_064336
Location (UCSC)
Chr 11: 67.36 – 67.37 Mb
Chr 19: 4.26 – 4.27 Mb
PubMed search
[3]
[4]
Wikidata
View/Edit Human
View/Edit Mouse
Cardiotrophin-like cytokine factor 1 (CLCF1), also known as Novel Neurotrophin-1 (NNT-1) or B cell-stimulating factor-3 (BSF-3), is a protein that in humans is encoded by the CLCF1 gene.[5]
^ abcGRCh38: Ensembl release 89: ENSG00000175505 – Ensembl, May 2017
^ abcGRCm38: Ensembl release 89: ENSMUSG00000040663 – Ensembl, May 2017
^"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
1 (CLCF1), also known as Novel Neurotrophin-1 (NNT-1) or B cell-stimulating factor-3 (BSF-3), is a protein that in humans is encoded by the CLCF1 gene...
IL-6 superfamily (Pfam PF00489), which also includes G-CSF, IL23A, and CLCF1. A viral version of IL6 is found in Kaposi's sarcoma-associated herpesvirus...
cytokine receptor activity Cellular component extracellular region CRLF-CLCF1 complex extracellular space cytosol external side of plasma membrane receptor...