Medication used in treatment of migraines
Zolmitriptan Trade names Zomig, others AHFS/Drugs.com Monograph MedlinePlus a601129 License data
US Zolmitriptan
Pregnancy Routes of By mouth, nasal spray ATC code Legal status Bioavailability 40% (oral) Protein binding 25% Metabolism Liver (CYP1A2-mediated, to active metabolite) Elimination half-life 3 hours Excretion Kidney (65%) and fecal (35%)
(S )-4-({3-[2-(Dimethylamino)ethyl]-1H -indol-5-yl}methyl)-1,3-oxazolidin-2-one
CAS Number 139264-17-8 Y PubChem CID IUPHAR/BPS DrugBank DB00315 Y ChemSpider 54844 Y UNII KEGG D00415 Y ChEBI CHEBI:10124 Y ChEMBL ChEMBL1185 Y CompTox Dashboard (EPA ) DTXSID8045933 ECHA InfoCard 100.158.186 Formula C 16 H 21 N 3 O 2 Molar mass −1 3D model (JSmol)
O=C1OC[C@@H](N1)Cc2ccc3c(c2)c(c[nH]3)CCN(C)C
InChI=1S/C16H21N3O2/c1-19(2)6-5-12-9-17-15-4-3-11(8-14(12)15)7-13-10-21-16(20)18-13/h3-4,8-9,13,17H,5-7,10H2,1-2H3,(H,18,20)/t13-/m0/s1
Y Key:ULSDMUVEXKOYBU-ZDUSSCGKSA-N
Y (verify)
Zolmitriptan , sold under the brand name Zomig among others, is a triptan used in the acute treatment of migraine attacks with or without aura and cluster headaches. It is a selective serotonin receptor agonist of the 1B and 1D subtypes.
It was patented in 1990 and approved for medical use in 1997.[2]
^ "Product monograph brand safety updates". Health Canada . 6 June 2024. Retrieved 8 June 2024 . ^ Fischer J, Ganellin CR (2006). Analogue-based Drug Discovery . John Wiley & Sons. p. 531. ISBN 9783527607495 .
Last Update: 2024-06-08T21:24:39Z
Zolmitriptan , sold under the brand name Zomig among others, is a triptan used in the acute treatment of migraine attacks with or without aura and cluster...
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Last Update: 2024-06-25T00:40:58Z
within twenty minutes of the headache's onset. Oral rizatriptan and nasal zolmitriptan are the most used triptans for migraines in children. Triptans should...
Word Count : 3652
Last Update: 2024-02-20T06:33:29Z
5-HT1B and 5-HT1D receptors. Like the other triptans sumatriptan and zolmitriptan , rizatriptan induces vasoconstriction—possibly by inhibiting the release...
Word Count : 669
Last Update: 2023-10-03T02:14:23Z
of migraine, it was found to have equal efficacy to rizatriptan and zolmitriptan . A Phase IIa clinical trial studying telcagepant for the prophylaxis...
Word Count : 303
Last Update: 2024-06-10T11:39:52Z
(5-HT) Triptans (e.g., avitriptan, donitriptan, eletriptan, sumatriptan, zolmitriptan ) TFMPP Tryptamines (e.g., 5-BT, 5-CT, 5-MT, DMT) Vortioxetine Antagonists:...
Word Count : 15793
Last Update: 2023-03-23T12:35:21Z
Bremen, Germany Zomig ZMT, a brand name for a dissolving tablet of zolmitriptan Maringarr language of Australia (ISO 639-3 code) Masset Airport, British...
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Last Update: 2024-06-26T19:14:56Z
(5-HT) Triptans (e.g., avitriptan, donitriptan, eletriptan, sumatriptan, zolmitriptan ) TFMPP Tryptamines (e.g., 5-BT, 5-CT, 5-MT, DMT) Vortioxetine Antagonists:...
Word Count : 11155
Last Update: 2024-06-21T20:35:47Z
Trastuzumab deruxtecan Vandetanib Vaxzevria Ximelagatran Zafirlukast Zolmitriptan Predecessors and acquired companies Astra AB Alexion Pharmaceuticals...
Word Count : 5551
Last Update: 2024-06-20T11:42:02Z
(5-HT) Triptans (e.g., avitriptan, donitriptan, eletriptan, sumatriptan, zolmitriptan ) TFMPP Tryptamines (e.g., 5-BT, 5-CT, 5-MT, DMT) Vortioxetine Antagonists:...
Word Count : 6533
Last Update: 2024-06-10T21:45:31Z
(5-HT) Triptans (e.g., avitriptan, donitriptan, eletriptan, sumatriptan, zolmitriptan ) TFMPP Tryptamines (e.g., 5-BT, 5-CT, 5-MT, DMT) Vortioxetine Antagonists:...
Word Count : 9106
Last Update: 2024-06-24T06:01:31Z
administration of cimetidine, the elimination half-life and area-under-curve of zolmitriptan and its active metabolites were roughly doubled. Cimetidine is a potent...
Word Count : 5133
Last Update: 2024-05-25T19:38:42Z
(5-HT) Triptans (e.g., avitriptan, donitriptan, eletriptan, sumatriptan, zolmitriptan ) TFMPP Tryptamines (e.g., 5-BT, 5-CT, 5-MT, DMT) Vortioxetine Antagonists:...
Word Count : 10014
Last Update: 2024-06-16T18:40:32Z
(5-HT) Triptans (e.g., avitriptan, donitriptan, eletriptan, sumatriptan, zolmitriptan ) TFMPP Tryptamines (e.g., 5-BT, 5-CT, 5-MT, DMT) Vortioxetine Antagonists:...
Word Count : 6166
Last Update: 2024-06-29T15:12:15Z
(5-HT) Triptans (e.g., avitriptan, donitriptan, eletriptan, sumatriptan, zolmitriptan ) TFMPP Tryptamines (e.g., 5-BT, 5-CT, 5-MT, DMT) Vortioxetine Antagonists:...
Word Count : 16718
Last Update: 2024-03-28T19:23:24Z
(5-HT) Triptans (e.g., avitriptan, donitriptan, eletriptan, sumatriptan, zolmitriptan ) TFMPP Tryptamines (e.g., 5-BT, 5-CT, 5-MT, DMT) Vortioxetine Antagonists:...
Word Count : 8663
Last Update: 2024-06-23T07:02:58Z
(5-HT) Triptans (e.g., avitriptan, donitriptan, eletriptan, sumatriptan, zolmitriptan ) TFMPP Tryptamines (e.g., 5-BT, 5-CT, 5-MT, DMT) Vortioxetine Antagonists:...
Word Count : 3947
Last Update: 2024-06-26T09:53:38Z
(5-HT) Triptans (e.g., avitriptan, donitriptan, eletriptan, sumatriptan, zolmitriptan ) TFMPP Tryptamines (e.g., 5-BT, 5-CT, 5-MT, DMT) Vortioxetine Antagonists:...
Word Count : 3454
Last Update: 2024-06-20T02:39:26Z
Trastuzumab deruxtecan Vandetanib Vaxzevria Ximelagatran Zafirlukast Zolmitriptan Predecessors and acquired companies Astra AB Alexion Pharmaceuticals...
Word Count : 3431
Last Update: 2024-05-29T19:34:52Z
(5-HT) Triptans (e.g., avitriptan, donitriptan, eletriptan, sumatriptan, zolmitriptan ) TFMPP Tryptamines (e.g., 5-BT, 5-CT, 5-MT, DMT) Vortioxetine Antagonists:...
Word Count : 12545
Last Update: 2024-06-24T22:43:06Z
(5-HT) Triptans (e.g., avitriptan, donitriptan, eletriptan, sumatriptan, zolmitriptan ) TFMPP Tryptamines (e.g., 5-BT, 5-CT, 5-MT, DMT) Vortioxetine Antagonists:...
Word Count : 10062
Last Update: 2024-06-09T04:55:43Z
(5-HT) Triptans (e.g., avitriptan, donitriptan, eletriptan, sumatriptan, zolmitriptan ) TFMPP Tryptamines (e.g., 5-BT, 5-CT, 5-MT, DMT) Vortioxetine Antagonists:...
Word Count : 5375
Last Update: 2024-06-09T14:24:06Z
(5-HT) Triptans (e.g., avitriptan, donitriptan, eletriptan, sumatriptan, zolmitriptan ) TFMPP Tryptamines (e.g., 5-BT, 5-CT, 5-MT, DMT) Vortioxetine Antagonists:...
Word Count : 4561
Last Update: 2024-06-11T06:12:16Z
(5-HT) Triptans (e.g., avitriptan, donitriptan, eletriptan, sumatriptan, zolmitriptan ) TFMPP Tryptamines (e.g., 5-BT, 5-CT, 5-MT, DMT) Vortioxetine Antagonists:...
Word Count : 1739
Last Update: 2024-06-03T02:15:23Z
(5-HT) Triptans (e.g., avitriptan, donitriptan, eletriptan, sumatriptan, zolmitriptan ) TFMPP Tryptamines (e.g., 5-BT, 5-CT, 5-MT, DMT) Vortioxetine Antagonists:...
Word Count : 5784
Last Update: 2024-06-26T05:52:53Z
(5-HT) Triptans (e.g., avitriptan, donitriptan, eletriptan, sumatriptan, zolmitriptan ) TFMPP Tryptamines (e.g., 5-BT, 5-CT, 5-MT, DMT) Vortioxetine Antagonists:...
Word Count : 10450
Last Update: 2024-06-08T17:23:40Z
addition to being 5-HT1B agonists, triptans (i.e. sumatriptan, almotriptan, zolmitriptan , naratriptan, eletriptan, frovatriptan and rizatriptan) are also agonists...
Word Count : 1657
Last Update: 2024-04-23T22:51:34Z
Zolmitriptan ...
Word Count : 2031
Last Update: 2024-05-18T06:03:21Z
(5-HT) Triptans (e.g., avitriptan, donitriptan, eletriptan, sumatriptan, zolmitriptan ) TFMPP Tryptamines (e.g., 5-BT, 5-CT, 5-MT, DMT) Vortioxetine Antagonists:...
Word Count : 2618
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