Metoclopramide is a medication used for stomach and esophageal problems.[5] It is commonly used to treat and prevent nausea and vomiting, to help with emptying of the stomach in people with delayed stomach emptying, and to help with gastroesophageal reflux disease.[6] It is also used to treat migraine headaches.[7]
Common side effects include: feeling tired, diarrhea, akathisia, and tardive dyskinesia. More serious side effects include neuroleptic malignant syndrome and depression.[6] It is thus rarely recommended that people take the medication for longer than twelve weeks.[6] No evidence of harm has been found after being taken by many pregnant women.[6][8] It belongs to the group of medications known as dopamine-receptor antagonists and works as a prokinetic.[6]
In 2012, metoclopramide was one of the top 100 most prescribed medications in the United States.[9] It is available as a generic medication.[6] It is on the World Health Organization's List of Essential Medicines.[10] In 2020, it was the 352nd most commonly prescribed medication in the United States, with more than 600,000 prescriptions.[11]
^Cite error: The named reference generics was invoked but never defined (see the help page).
^"Metoclopramide Use During Pregnancy". Drugs.com. 27 February 2020. Retrieved 22 November 2020.
^"FDA-sourced list of all drugs with black box warnings (Use Download Full Results and View Query links.)". nctr-crs.fda.gov. FDA. Retrieved 22 October 2023.
^Cite error: The named reference Reglan FDA label was invoked but never defined (see the help page).
^"Metoclopramide". MedlinePlus. Retrieved 22 November 2020.
^ abcdef"Metoclopramide hydrochloride". Monograph. The American Society of Health-System Pharmacists. Retrieved 27 September 2014.
^"Prescribing medicines in pregnancy database". Australian Government. 3 March 2014. Retrieved 22 April 2014.
^Bartholow M. "Top 200 Drugs of 2012". Pharmacy Times. Archived from the original on 17 May 2014. Retrieved 22 April 2014.
^World Health Organization (2021). World Health Organization model list of essential medicines: 22nd list (2021). Geneva: World Health Organization. hdl:10665/345533. WHO/MHP/HPS/EML/2021.02.
^"Metoclopramide - Drug Usage Statistics". ClinCalc. Retrieved 7 October 2022.
Metoclopramide is a medication used for stomach and esophageal problems. It is commonly used to treat and prevent nausea and vomiting, to help with emptying...
are different from those of other dopamine receptor antagonists like metoclopramide and it produces little in the way of central nervous system adverse...
related to metoclopramide. A small Spanish study found that more adverse reactions are reported with clebopride than with metoclopramide, particularly...
prokinetic properties widely used as an antiemetic, closely related to metoclopramide. It is not available in the United States. Bromopride appears to be...
antipsychotic and antidepressant activity. Other benzamide derivatives include metoclopramide, tiapride, and sultopride. Sulpiride Veralipride Benzamide "Levosulpiride...
commonly used to treat GI stasis in rabbits, sometimes in conjunction with metoclopramide (Reglan). Oral bioavailability of cisapride is approximately 33%. It...
including postoperative nausea and vomiting. It is structurally related to metoclopramide and other benzamides. Ballatori E, Roila F (September 2003). "Impact...
of dopamine-receptor-blocking medications such as antipsychotics and metoclopramide. These medications are usually used for mental illness but may also...
lower rates of EPS. Other anti-dopaminergic drugs, like the antiemetic metoclopramide, can also result in extrapyramidal side effects. Short and long-term...
ondansetron are equally effective; droperidol is more effective than metoclopramide. It has also been used as an antipsychotic in doses ranging from 5 to...
treat low milk supply. Synthetic galactagogues such as domperidone and metoclopramide interact with the dopamine system in such a way to increase the production...
chlorpromazine and metoclopramide for centrally mediated vomiting induced by apomorphine or xylazine. It works better than chlorpromazine and metoclopramide for vomiting...
side-effect may also include selective serotonin reuptake inhibitors, metoclopramide, and reserpine, though any medication listing agitation as a side effect...
blood–brain barrier and hence to have peripheral selectivity, in contrast to metoclopramide but similarly to domperidone. Unlike domperidone however, metopimazine...
poor, and following a safety review, licensed use of domperidone and metoclopramide is now restricted to short-term use in nausea and vomiting only. To...
rare extrapyramidal side effect of phenothiazines, haloperidol, and metoclopramide.[citation needed] Opisthotonus with the presence of the risus sardonicus...
reflux and medication-induced nausea (such as that from chemotherapy): metoclopramide (Reglan) and domperidone; less often, alpha-methyldopa and reserpine...
effects and side effects of pethidine may be increased. Metoclopramide : Action of metoclopramide is decreased. Alcohol : Risk of serious intoxication....
effects and side effects of pethidine may be increased. Metoclopramide : Action of metoclopramide is decreased. Alcohol : Risk of serious intoxication....
The most commonly prescribed antiemetics in the US are promethazine, metoclopramide, and the newer ondansetron. The word nausea is from Latin nausea, from...
the Yoruba people Itan, a trade name used in Chile for a medication (Metoclopramide) used to treat digestive problems iTAN, Indexed Transaction authentication...
antiemetic efficacy of secobarbital and chlorpromazine compared to metoclopramide, diphenhydramine, and dexamethasone. A randomized trial". Cancer. 58...
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