clathrin-sculpted monoamine transport vesicle membrane
endoplasmic reticulum membrane
membrane
endoplasmic reticulum
cytoplasmic vesicle membrane
cytoplasmic vesicle
integral component of plasma membrane
cell junction
synaptic vesicle membrane
synapse
terminal bouton
Biological process
xenobiotic transmembrane transport
monoamine transport
neurotransmitter transport
aminergic neurotransmitter loading into synaptic vesicle
serotonin transport
transmembrane transport
serotonin uptake
xenobiotic transport
Sources:Amigo / QuickGO
Orthologs
Species
Human
Mouse
Entrez
6570
110877
Ensembl
ENSG00000036565
ENSMUSG00000036330
UniProt
P54219
Q8R090
RefSeq (mRNA)
NM_001135691 NM_001142324 NM_001142325 NM_003053
NM_153054
RefSeq (protein)
NP_001129163 NP_001135796 NP_001135797 NP_003044
NP_694694
Location (UCSC)
Chr 8: 20.14 – 20.18 Mb
Chr 8: 69.49 – 69.54 Mb
PubMed search
[3]
[4]
Wikidata
View/Edit Human
View/Edit Mouse
Vesicular monoamine transporter 1 (VMAT1) also known as chromaffin granule amine transporter (CGAT) or solute carrier family 18 member 1 (SLC18A1) is a protein that in humans is encoded by the SLC18A1 gene. VMAT1 is an integral membrane protein, which is embedded in synaptic vesicles and serves to transfer monoamines, such as norepinephrine, epinephrine, dopamine, and serotonin, between the cytosol and synaptic vesicles.[5] SLC18A1 is an isoform of the vesicular monoamine transporter.
^ abcGRCh38: Ensembl release 89: ENSG00000036565 – Ensembl, May 2017
^ abcGRCm38: Ensembl release 89: ENSMUSG00000036330 – Ensembl, May 2017
^"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^Eiden LE, Schäfer MK, Weihe E, Schütz B (February 2004). "The vesicular amine transporter family (SLC18): amine/proton antiporters required for vesicular accumulation and regulated exocytotic secretion of monoamines and acetylcholine". Pflügers Arch. 447 (5): 636–40. doi:10.1007/s00424-003-1100-5. PMID 12827358. S2CID 20764857.
and 29 Related for: Vesicular monoamine transporter 1 information
Vesicularmonoaminetransporter1 (VMAT1) also known as chromaffin granule amine transporter (CGAT) or solute carrier family 18 member 1 (SLC18A1) is a...
solute carrier family 18 member 2 (SLC18A2) also known as vesicularmonoaminetransporter 2 (VMAT2) is a protein that in humans is encoded by the SLC18A2...
The vesicularmonoaminetransporter (VMAT) is a transport protein integrated into the membranes of synaptic vesicles of presynaptic neurons. It transports...
Monoaminetransporters (MATs) are proteins that function as integral plasma-membrane transporters to regulate concentrations of extracellular monoamine...
The plasma membrane monoaminetransporter (PMAT) is a low-affinity monoaminetransporter protein which in humans is encoded by the SLC29A4 gene. It is...
Vesicular glutamate transporter1 (VGLUT1) is a protein that in humans is encoded by the SLC17A7 gene. The protein encoded by this gene is a vesicle-bound...
that in humans is encoded by the SLC6A4 gene. SERT is a type of monoaminetransporter protein that transports the neurotransmitter serotonin from the...
by the solute carrier family 6 member 2 (SLC6A2) gene. NET is a monoaminetransporter and is responsible for the sodium-chloride (Na+/Cl−)-dependent reuptake...
widely accepted model for monoaminetransporter function, sodium ions must bind to the extracellular domain of the transporter before dopamine can bind...
Vesicular inhibitory amino acid transporter is a protein that in humans is encoded by the SLC32A1 gene. The protein encoded by this gene is an integral...
neuron, they may inhibit the reuptake of monoamine neurotransmitters through vesicularmonoaminetransporter 2 (VMAT2) and release the neurotransmitters...
is influenced by heredity and that a specific gene, called vesicularmonoaminetransporter 2 (VMAT2), predisposes humans towards spiritual or mystic experiences...
medication used to treat tardive dyskinesia. It acts as a vesicularmonoaminetransporter 2 (VMAT2) inhibitor. Valbenazine is used to treat tardive dyskinesia...
Vesicular glutamate transporter 3 (VGLUT3) is a protein that in humans is encoded by the SLC17A8 gene. This gene encodes a vesicular glutamate transporter...
Glucose transporters are a wide group of membrane proteins that facilitate the transport of glucose across the plasma membrane, a process known as facilitated...
glutamate transporters is composed of two primary subclasses: the excitatory amino acid transporter (EAAT) family and vesicular glutamate transporter (VGLUT)...
For example, certain proteins such as the dopamine transporter (DAT), vesicularmonoaminetransporter 2 (VMAT2), and dopamine receptors can be classified...
respective monoaminetransporters (MATs), which include the serotonin transporter (SERT), norepinephrine transporter (NET), and dopamine transporter (DAT)...
releases these neurotransmitters from synaptic vesicles via vesicularmonoaminetransporter 2. It also shares many chemical and pharmacological properties...
the synaptic cleft via monoaminetransporter-mediated release) by triggering reverse transport at vesicularmonoaminetransporters (specifically, VMAT1...
of selectivity for the other monoaminetransporters, with pure SSRIs having strong affinity for the serotonin transporter and only weak affinity for the...
The Vesicular acetylcholine transporter (VAChT) is a neurotransmitter transporter which is responsible for loading acetylcholine (ACh) into secretory...
to trace amine-associated receptor 1 (TAAR1) and inhibiting vesicularmonoaminetransporter 2 (VMAT2) in monoamine neurons. To a lesser extent, it also...
Global Information
