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Monoamine releasing agent information


Amphetamine, the prototypical monoamine releasing agent, which acts on norepinephrine and dopamine.

A monoamine releasing agent (MRA), or simply monoamine releaser, is a drug that induces the release of a monoamine neurotransmitter from the presynaptic neuron into the synapse, leading to an increase in the extracellular concentrations of the neurotransmitter. Many drugs induce their effects in the body and/or brain via the release of monoamine neurotransmitters, e.g., trace amines, many substituted amphetamines, and related compounds.

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Monoamine releasing agent

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A monoamine releasing agent (MRA), or simply monoamine releaser, is a drug that induces the release of a monoamine neurotransmitter from the presynaptic...

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Serotonin releasing agent

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releasing agent (SRA) is a type of drug that induces the release of serotonin into the neuronal synaptic cleft. A selective serotonin releasing agent...

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Dopamine releasing agent

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releasing agents, or SNDRAs), however. Serotonin–dopamine releasing agents are much rarer and are not selective for monoamine release. Examples...

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Norepinephrine releasing agent

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also release dopamine to a much lesser extent, however, and bupropion is also a nicotinic acetylcholine receptor antagonist. Monoamine releasing agent Serotonin...

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Monoamine reuptake inhibitor

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methamphetamine), which do act to some extent as monoamine reuptake inhibitors, exerts their effects primarily as releasing agents. Additionally, psychostimulants acting...

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Monoaminergic

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drugs include monoamine precursors, monoamine receptor modulators, monoamine reuptake inhibitors, monoamine releasing agents, and monoamine metabolism modulators...

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Monoamine oxidase inhibitor

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Monoamine oxidase inhibitors (MAOIs) are a class of drugs that inhibit the activity of one or both monoamine oxidase enzymes: monoamine oxidase A (MAO-A)...

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Mesembrine

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Sceletium extract" may exert anti-depressant effects by acting as a monoamine releasing agent." As such, mesembrine likely plays a dominant role in the antidepressant...

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List of investigational antidepressants

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Midomafetamine (MDMA; ecstasy) – serotonin–norepinephrine–dopamine releasing agent (SNDRA) [10] Tramadol (ETS6103; Viotra) – μ-opioid receptor agonist...

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Monoamine transporter

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Monoamine transporters (MATs) are proteins that function as integral plasma-membrane transporters to regulate concentrations of extracellular monoamine...

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Vesicular monoamine transporter 2

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The solute carrier family 18 member 2 (SLC18A2) also known as vesicular monoamine transporter 2 (VMAT2) is a protein that in humans is encoded by the SLC18A2...

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Monoamine activity enhancer

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that enhance the release of monoamines in the nervous system. Monoamine activity enhancers are distinct from monoamine releasing agents in that they do...

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MDMA

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and a monoamine-releasing agent mechanistically. Like other monoamine-releasing agents, MDMA enters monoaminergic neurons through monoamine transporters...

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Monoamine oxidase A

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Monoamine oxidase A, also known as MAO-A, is an enzyme (E.C. 1.4.3.4) that in humans is encoded by the MAOA gene. This gene is one of two neighboring...

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Releaser

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The term releaser may refer to: Monoamine releasing agent A type of stimulus that can elicit a fixed action pattern Acoustic release This disambiguation...

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Monoamine oxidase

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Monoamine oxidases (MAO) (EC 1.4.3.4) are a family of enzymes that catalyze the oxidation of monoamines, employing oxygen to clip off their amine group...

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Mesembryanthemum cordifolium

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(A. cordifolia) contains the serotonin reuptake inhibitor and monoamine releasing agent alkaloid mesembrine and demethylmesembrenol. It was found to contain...

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Methylphenidate

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amphetamine reduces firing rate, but causes monoamine release by reversing the flow of the monoamines through monoamine transporters via a diverse set of mechanisms...

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Methamnetamine

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known as methylnaphetamine, MNA, MNT and PAL-1046) is a triple monoamine releasing agent and N-methyl analog of the non-neurotoxic experimental drug naphthylaminopropane...

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Methamphetamine

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hypersensitivity reactions to other stimulants in the past or are currently taking monoamine oxidase inhibitors should not take methamphetamine. The FDA also advises...

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Norepinephrine reuptake inhibitor

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than the other two monoamine transporters (MATs) are listed here. For a list of NRIs that act at multiple MATs, see the other monoamine reuptake inhibitor...

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MRA

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Magnetic resonance angiography Mineralocorticoid receptor antagonist Monoamine releasing agent Multiresolution analysis Madison-Ridgeland Academy Maharashtra...

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Mesembryanthemum tortuosum

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(2016-01-11). "High-mesembrine Sceletium extract (Trimesemine™) is a monoamine releasing agent, rather than only a selective serotonin reuptake inhibitor". Journal...

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