Specific granules are secretory vesicles found exclusively in cells of the immune system called granulocytes.
It is sometimes described as applying specifically to neutrophils,[1] and sometimes the term is applied to other types of cells.[2]
These granules store a mixture of cytotoxic molecules, including many enzymes and antimicrobial peptides, that are released by a process called degranulation following activation of the granulocyte by an immune stimulus.
Specific granules are also known as "secondary granules".[3]
^"Definition: specific granule from Online Medical Dictionary".
^Okuda M, Takenaka T, Kawabori S, Ogami Y (July 1981). "Ultrastructural study of the specific granule of the human eosinophil". J. Submicrosc. Cytol. 13 (3): 465–71. PMID 7334549.
^John P. Greer; Maxwell Myer Wintrobe (1 December 2008). Wintrobe's clinical hematology. Lippincott Williams & Wilkins. pp. 173–. ISBN 978-0-7817-6507-7. Retrieved 10 November 2010.
Specificgranules are secretory vesicles found exclusively in cells of the immune system called granulocytes. It is sometimes described as applying specifically...
type-specific features of unknown function Azurophilic granule, a structure characteristic of the azurophil eukaryotic cell type Chromaffin granule, a structure...
with specific flavors or other characteristics Specificgranule, secretory vesicle in granulocytes Specific immunity, to a particular pathogen Specific Pathogen...
innate immune system characterized by the presence of specificgranules in their cytoplasm. Such granules distinguish them from the various agranulocytes....
Soter NA, Austen KF (August 1984). "Localization of histaminase to the specificgranule of the human neutrophil". Immunology. 52 (4): 649–658. PMC 1454675...
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between cobalamins and their natural analogues during their binding to the specific B12-transporting proteins". Biochemistry. 46 (21): 6446–58. doi:10.1021/bi062063l...
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membrane extrinsic component of membrane extracellular region specificgranule lumen tertiary granule lumen anchored component of external side of plasma membrane...
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encoding different protein isoforms have been described for this gene. Specificity of vesicular transport is regulated, in part, by the interaction of a...
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