FOLR3 information

FOLR3
Identifiers
Aliases	FOLR3, FR-G, FR-gamma, gamma-hFR, folate receptor 3 (gamma), folate receptor 3, folate receptor gamma, FRgamma
External IDs	OMIM: 602469; HomoloGene: 88342; GeneCards: FOLR3; OMA:FOLR3 - orthologs
Gene location (Human)
Chr.	Chromosome 11 (human)
End	72,139,892 bp
RNA expression pattern
	Top expressed in
	granulocyte; ; blood; ; monocyte; ; bone marrow; ; stromal cell of endometrium; ; spleen; ; bone marrow cells; ; trabecular bone; ; human kidney; ; gonad;
	n/a
	More reference expression data
	n/a
Gene ontology
Molecular function	folic acid binding; signaling receptor activity;
Cellular component	membrane; extrinsic component of membrane; extracellular region; specific granule lumen; tertiary granule lumen; anchored component of external side of plasma membrane;
Biological process	folic acid transport; neutrophil degranulation; cell adhesion; fusion of sperm to egg plasma membrane involved in single fertilization; sperm-egg recognition;
	Sources:Amigo / QuickGO
Orthologs
	2352
	n/a
	ENSG00000110203
	n/a
	P41439
	n/a
	NM_000804; NM_001318045
	n/a
	NP_000795; NP_001304974
	n/a
	Wikidata
View/Edit Human

Folate receptor gamma is a protein that in humans is encoded by the FOLR3 gene. It is involved in up-take of folic acid.^[3]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000110203 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Kelemen LE (July 2006). "The role of folate receptor alpha in cancer development, progression and treatment: cause, consequence or innocent bystander?". International Journal of Cancer. 119 (2): 243–250. doi:10.1002/ijc.21712. PMID 16453285. S2CID 1966455.

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