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Granulocyte information


Granulocyte
Types of granulocytes
Details
SystemImmune system
Identifiers
MeSHD006098
FMA62854
Anatomical terms of microanatomy
[edit on Wikidata]

Granulocytes are cells in the innate immune system characterized by the presence of specific granules in their cytoplasm.[1] Such granules distinguish them from the various agranulocytes. All myeloblastic granulocytes are polymorphonuclear, that is, they have varying shapes (morphology) of the nucleus (segmented, irregular; often lobed into three segments); and are referred to as polymorphonuclear leukocytes (PMN, PML, or PMNL). In common terms, polymorphonuclear granulocyte refers specifically to "neutrophil granulocytes",[2] the most abundant of the granulocytes; the other types (eosinophils, basophils, and mast cells) have varying morphology. Granulocytes are produced via granulopoiesis in the bone marrow.

  1. ^ WebMD (2009). "granulocyte". Webster's New World Medical Dictionary (3rd ed.). Houghton Mifflin Harcourt. p. 181. ISBN 978-0-544-18897-6.
  2. ^ WebMD (2009). "leukocyte, polymorphonuclear". Webster's New World Medical Dictionary (3rd ed.). Houghton Mifflin Harcourt. p. 244. ISBN 978-0-544-18897-6.

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Granulocyte

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Granulopoiesis

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is a part of haematopoiesis, that leads to the production of granulocytes. A granulocyte, also referred to as a polymorphonuclear leukocyte (PMN), is...

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Granulocyte transfusion

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A granulocyte transfusion is a medical procedure in which granulocytes (a type of white blood cell) are infused into a person's blood. Granulocyte transfusions...

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Eosinophil

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also control mechanisms associated with allergy and asthma. They are granulocytes that develop during hematopoiesis in the bone marrow before migrating...

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Basophil

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common type of granulocyte, representing about 0.5% to 1% of circulating white blood cells. However, they are the largest type of granulocyte and how they...

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Immunodeficiency

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as of neutrophil granulocytes (termed neutropenia). Granulocyte deficiencies also include decreased function of individual granulocytes, such as in chronic...

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Haematopoiesis

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Granulopoiesis (or granulocytopoiesis) is haematopoiesis of granulocytes, except mast cells which are granulocytes but with an extramedullar maturation. Thrombopoiesis...

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Neutrophil

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white blood cell. More specifically, they form the most abundant type of granulocytes and make up 40% to 70% of all white blood cells in humans. They form...

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GEMM

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Electronic Music Marketplace, a former online music market CFU-GEMM, granulocyte-erythrocyte-monocyte-megakaryocyte colony forming unit Gem (disambiguation)...

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Basophilic

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this term refers to: basophil granulocytes anterior pituitary basophils An abnormal increase in basophil granulocytes is therefore also described as...

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White blood cell

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and foreign invaders. White blood cells include three main subtypes: granulocytes, lymphocytes and monocytes. All white blood cells are produced and derived...

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Myeloblast

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a unipotent stem cell which differentiates into the effectors of the granulocyte series. It is found in the bone marrow. Stimulation of myeloblasts by...

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Agranulocytosis

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their suppressed immune system. In agranulocytosis, the concentration of granulocytes (a major class of white blood cells that includes neutrophils, basophils...

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Band cell

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granulopoiesis, derived from a metamyelocyte, and leading to a mature granulocyte. It is characterized by having a curved but not lobular nucleus. The...

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List of immune cells

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responses Basophil Granulocyte Basophil Basophilic granulocyte 12-15 Release histamine for inflammatory responses Mast Cell Granulocyte Mast Cell Mastocyte...

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TNF inhibitor

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Peginesatide Pegol sihematide (EPO-018B) G-CSF (CSF3) Agonists: Filgrastim Granulocyte colony-stimulating factor Lenograstim Leridistim Lipegfilgrastim Nartograstim...

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Wound healing

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Smooth muscle cells Keratinocytes Granulocyte, macrophage, fibroblast and smooth muscle cell chemotaxis Granulocyte, macrophage and fibroblast activation...

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counts are elevated. According to one hypothesis, these inflammatory granulocytes may have been depleted in past episodes of vigorous inflammation. Because...

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Lobation

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granulocytes, which are types of white blood cells, where the nucleus is segmented into two or more connected lobes. Of the four types of granulocyte...

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Agranulocyte

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type being granulocytes. Agranular cells are noted by the absence of granules in their cytoplasm, which distinguishes them from granulocytes. Leukocytes...

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Adipokine

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Peginesatide Pegol sihematide (EPO-018B) G-CSF (CSF3) Agonists: Filgrastim Granulocyte colony-stimulating factor Lenograstim Leridistim Lipegfilgrastim Nartograstim...

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Eosinophilic

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A basophil granulocyte is surrounded by lightly staining eosinophilic erythrocytes in an H&E staining....

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Promyelocyte

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A promyelocyte (or progranulocyte) is a granulocyte precursor, developing from the myeloblast and developing into the myelocyte. Promyelocytes measure...

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Monocyte

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monocytes can differentiate into dendritic cells by adding the cytokines granulocyte macrophage colony-stimulating factor (GM-CSF) and interleukin 4. Such...

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Growth factor

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Macrophage colony-stimulating factor (M-CSF) Granulocyte colony-stimulating factor (G-CSF) Granulocyte macrophage colony-stimulating factor (GM-CSF)...

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