Monoamine activity enhancer is a term coined in the academic literature with substantial research.
Monoamine activity enhancers (MAE), also known as catecholaminergic/serotoninergic activity enhancers, are a class neuro-biologically active compounds that enhance the release of monoamines in the nervous system. Monoamine activity enhancers are distinct from monoamine releasing agents in that they do not cause the release of monoamines from synaptic vesicles but rather potentiate impulse-evoked monoamine-release.[1][2] Monoamine activity enhancers increase the number of monoamines released per electrical impulse received.[1][2]
^ abShimazu, Seiichiro; Miklya, Ildikó (2004-05-01). "Pharmacological studies with endogenous enhancer substances: β-phenylethylamine, tryptamine, and their synthetic derivatives". Progress in Neuro-Psychopharmacology and Biological Psychiatry. 28 (3): 421–427. doi:10.1016/j.pnpbp.2003.11.016. ISSN 0278-5846. PMID 15093948. S2CID 37564231.
enhancing the release of a certain monoamine over others. For example, the endogenous monoamineactivityenhancer phenylethylamine (PEA) is roughly 100x...
Monoamine oxidase A, also known as MAO-A, is an enzyme (E.C. 1.4.3.4) that in humans is encoded by the MAOA gene. This gene is one of two neighboring...
Monoamine transporters (MATs) are proteins that function as integral plasma-membrane transporters to regulate concentrations of extracellular monoamine...
Monoamine oxidase inhibitors (MAOIs) are a class of drugs that inhibit the activity of one or both monoamine oxidase enzymes: monoamine oxidase A (MAO-A)...
A monoamine releasing agent (MRA), or simply monoamine releaser, is a drug that induces the release of a monoamine neurotransmitter from the presynaptic...
and narcolepsy. It is also used as an athletic performance and cognitive enhancer, and recreationally as an aphrodisiac and euphoriant. The amphetamine molecule...
Monoamine oxidase B, also known as MAO-B, is an enzyme that in humans is encoded by the MAOB gene. The protein encoded by this gene belongs to the flavin...
amine-associated receptor 1 in the functional regulation of monoamine transporters and dopaminergic activity". Journal of Neurochemistry. 116 (2): 164–176. doi:10...
The solute carrier family 18 member 2 (SLC18A2) also known as vesicular monoamine transporter 2 (VMAT2) is a protein that in humans is encoded by the SLC18A2...
The vesicular monoamine transporter (VMAT) is a transport protein integrated into the membranes of synaptic vesicles of presynaptic neurons. It transports...
of drug abuse are allergic to sympathomimetic amine drugs are taking a monoamine oxidase inhibitor (MAOI) or have taken one within the last 14 days have...
depression. Amphetamine is also used as an athletic performance enhancer and cognitive enhancer, and recreationally as an aphrodisiac and euphoriant. It is...
metabolite of the antiparkinson's drug selegiline. Selegiline, a selective monoamine oxidase B (MAOB) inhibitor at low doses, is also metabolized into levomethamphetamine...
product with naltrexone. Amfepramone itself lacks any affinity for the monoamine transporters and instead functions as a prodrug to ethcathinone. Ethcathinone...
catecholaminergic activityenhancer when present in minuscule concentrations far below those at which monoamine oxidase inhibitory activity can be observed...
phenylethylamine and tryptamine have been identified as endogenous "activityenhancers". Monoamine oxidase (MAO) inhibitors (MAOIs) including nonselective agents...
natural monoamine alkaloid, and trace amine, which acts as a central nervous system stimulant in humans. In the brain, phenethylamine regulates monoamine neurotransmission...
phenothiazines, hypertension, and pheochromocytoma. Patients receiving monoamine oxidase inhibitors. For shock due to loss of blood or fluid, give fluid...
encoded by the solute carrier family 6 member 2 (SLC6A2) gene. NET is a monoamine transporter and is responsible for the sodium-chloride (Na+/Cl−)-dependent...
in children is unclear. Concomitant or recent (previous fourteen days) monoamine oxidase inhibitor use can lead to hypertensive reactions, including hypertensive...
structurally and metabolically related to classical monoamine neurotransmitters. Compared to the classical monoamines, they are present in trace concentrations...
or no efficacy in producing neurotransmitter efflux at other types of monoamine neurons. SSRAs have been used clinically as appetite suppressants, and...
narcolepsy. It is also used illicitly as an athletic performance enhancer, cognitive enhancer, appetite suppressant, and recreationally as a euphoriant. It...
amine-associated receptor 1 in the functional regulation of monoamine transporters and dopaminergic activity". J. Neurochem. 116 (2): 164–176. doi:10.1111/j.1471-4159...
protein that in humans is encoded by the SLC6A4 gene. SERT is a type of monoamine transporter protein that transports the neurotransmitter serotonin from...
of monoamine oxidase inhibitors (MAOIs). Tyramine occurs widely in plants and animals, and is metabolized by various enzymes, including monoamine oxidases...
of PPA. Exogenous compounds in this family are degraded too rapidly by monoamine oxidase to be active at all but the highest doses. However, the addition...