positive regulation of pathway-restricted SMAD protein phosphorylation
positive regulation of sarcomere organization
positive regulation of cell proliferation involved in heart morphogenesis
cardiac muscle cell proliferation
positive regulation of cardiac muscle hypertrophy
negative regulation of endothelial cell migration
positive regulation of transcription, DNA-templated
ventricular cardiac muscle tissue morphogenesis
multicellular organism development
heart development
positive regulation of gene expression
cell adhesion
negative regulation of cell migration
positive regulation of cardiac muscle cell proliferation
positive regulation of cartilage development
negative regulation of cell growth
regulation of cardiac muscle hypertrophy in response to stress
atrial cardiac muscle tissue morphogenesis
regulation of cardiac muscle contraction
sarcomere organization
ventricular cardiac muscle cell development
activin receptor signaling pathway
BMP signaling pathway
regulation of signaling receptor activity
cell development
Sources:Amigo / QuickGO
Orthologs
Species
Human
Mouse
Entrez
27302
12154
Ensembl
ENSG00000163217
ENSMUSG00000030046
UniProt
O95393
Q9R229
RefSeq (mRNA)
NM_014482
NM_009756
RefSeq (protein)
NP_055297
NP_033886
Location (UCSC)
Chr 2: 68.86 – 68.87 Mb
Chr 6: 87.41 – 87.41 Mb
PubMed search
[3]
[4]
Wikidata
View/Edit Human
View/Edit Mouse
Bone morphogenetic protein 10 (BMP10) is a protein that in humans is encoded by the BMP10 gene.[5][6]
BMP10 is a polypeptide belonging to the TGF-β superfamily of proteins.[6] It is a novel protein that, unlike most other BMP's, is likely to be involved in the trabeculation of the heart. Bone morphogenetic proteins are known for their ability to induce bone and cartilage development. BMP10 is categorized as a BMP since it shares a large sequence homology with other BMP's in the TGF-β superfamily.
^ abcGRCh38: Ensembl release 89: ENSG00000163217 – Ensembl, May 2017
^ abcGRCm38: Ensembl release 89: ENSMUSG00000030046 – Ensembl, May 2017
^"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Entrez Gene: bone morphogenetic protein 10".
^ abNeuhaus H, Rosen V, Thies RS (February 1999). "Heart specific expression of mouse BMP-10 a novel member of the TGF-beta superfamily". Mech. Dev. 80 (2): 181–4. doi:10.1016/S0925-4773(98)00221-4. PMID 10072785. S2CID 15626081.
and 24 Related for: Bone morphogenetic protein 10 information
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component in the coupling of bone formation and its resorption during bone remodeling. Bonemorphogeneticproteins (BMPs) are proteins that are made of acidic...
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