negative regulation of transcription, DNA-templated
positive regulation of odontogenesis
positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus
negative regulation of aldosterone biosynthetic process
positive regulation of osteoblast proliferation
response to hypoxia
positive regulation of endothelial cell proliferation
positive regulation of cell migration
negative regulation of cortisol biosynthetic process
cell-cell signaling
positive regulation of pathway-restricted SMAD protein phosphorylation
cellular response to growth factor stimulus
cellular response to BMP stimulus
cardiac muscle tissue morphogenesis
endocardial cushion morphogenesis
multicellular organism development
negative regulation of cardiac muscle cell differentiation
positive regulation of apoptotic process
negative regulation of insulin-like growth factor receptor signaling pathway
positive regulation of transcription by RNA polymerase II
cardiac epithelial to mesenchymal transition
positive regulation of pri-miRNA transcription by RNA polymerase II
positive regulation of gene expression
BMP signaling pathway
cardiac muscle cell differentiation
cell development
regulation of signaling receptor activity
negative regulation of gene expression
response to bacterium
regulation of apoptotic process
regulation of MAPK cascade
Sources:Amigo / QuickGO
Orthologs
Species
Human
Mouse
Entrez
650
12156
Ensembl
ENSG00000125845
ENSMUSG00000027358
UniProt
P12643
P21274
RefSeq (mRNA)
NM_001200
NM_007553
RefSeq (protein)
NP_001191
NP_031579
Location (UCSC)
Chr 20: 6.77 – 6.78 Mb
Chr 2: 133.39 – 133.4 Mb
PubMed search
[3]
[4]
Wikidata
View/Edit Human
View/Edit Mouse
Bone morphogenetic protein 2 or BMP-2 belongs to the TGF-β superfamily of proteins.[5]
^ abcGRCh38: Ensembl release 89: ENSG00000125845 – Ensembl, May 2017
^ abcGRCm38: Ensembl release 89: ENSMUSG00000027358 – Ensembl, May 2017
^"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^Sampath TK, Coughlin JE, Whetstone RM, Banach D, Corbett C, Ridge RJ, Ozkaynak E, Oppermann H, Rueger DC (August 1990). "Bovine osteogenic protein is composed of dimers of OP-1 and BMP-2A, two members of the transforming growth factor-beta superfamily". J. Biol. Chem. 265 (22): 13198–205. doi:10.1016/S0021-9258(19)38285-7. PMID 2376592.
and 28 Related for: Bone morphogenetic protein 2 information
Bonemorphogeneticprotein2 or BMP-2 belongs to the TGF-β superfamily of proteins. BMP-2 like other bonemorphogeneticproteins, plays an important role...
Bonemorphogeneticproteins (BMPs) are a group of growth factors also known as cytokines and as metabologens. Originally discovered by their ability to...
Bonemorphogeneticprotein 8B is a protein that in humans is encoded by the BMP8B gene. The protein encoded by this gene is a member of the TGF-β superfamily...
Bonemorphogeneticprotein 7 or BMP7 (also known as osteogenic protein-1 or OP-1) is a protein that in humans is encoded by the BMP7 gene. The protein...
Bonemorphogeneticprotein 6 is a protein that in humans is encoded by the BMP6 gene. The protein encoded by this gene is a member of the TGFβ superfamily...
four bonemorphogeneticprotein receptors: Bonemorphogeneticprotein receptor, type 1: ACVR1 BMPR1A BMPR1B Bonemorphogeneticprotein receptor, type 2 Both...
Bonemorphogeneticprotein 1, also known as BMP1, is a protein which in humans is encoded by the BMP1 gene. There are seven isoforms of the protein created...
Bonemorphogeneticprotein 10 (BMP10) is a protein that in humans is encoded by the BMP10 gene. BMP10 is a polypeptide belonging to the TGF-β superfamily...
Bonemorphogeneticprotein 5 is a protein that in humans is encoded by the BMP5 gene. The protein encoded by this gene is member of the TGFβ superfamily...
Bonemorphogeneticprotein 3, also known as osteogenin, is a protein in humans that is encoded by the BMP3 gene. The protein encoded by this gene is a...
The bonemorphogeneticprotein receptor, type IA also known as BMPR1A is a protein which in humans is encoded by the BMPR1A gene. BMPR1A has also been...
Bonemorphogeneticprotein 8A (BMP8A) is a protein that in humans is encoded by the BMP8A gene. BMP8A is a polypeptide member of the TGFβ superfamily of...
Bonemorphogeneticprotein 15 (BMP-15) is a protein that in humans is encoded by the BMP15 gene. It is involved in folliculogenesis, the process in which...
Bonemorphogeneticprotein receptor type-1B also known as CDw293 (cluster of differentiation w293) is a protein that in humans is encoded by the BMPR1B...
Bonemorphogeneticprotein receptor type II or BMPR2 is a serine/threonine receptor kinase encoded by the BMPR2 gene. It binds bonemorphogenetic proteins...
BMP2 or BMP-2 may refer to: Bonemorphogeneticprotein2 Boyevaya Mashina Pekhoty (BMP-2), a Soviet infantry fighting vehicle BMP (disambiguation) BMP1...
liver is highly dependent upon signals originating here. Bonemorphogeneticprotein2 (BMP-2), BMP-4 and BMP-7 produced from the septum transversum join...
171 Zhao, M.; Berry, J.E.; Somerman, M.J. (1 January 2003). "BoneMorphogeneticProtein-2 Inhibits Differentiation and Mineralization of Cementoblasts...
human osteoblast differentiation through bonemorphogeneticprotein-2/extracellular signal-regulated kinase 1/2 pathway. Syringetin is formed from laricitrin...
PMC 2707782. PMID 18684741. Park, G. T.; Morasso, M. I. (2002). "Bonemorphogeneticprotein-2 (BMP-2) transactivates Dlx3 through Smad1 and Smad4: Alternative...
small tears in the annulus and inflammation of the nerve root. Bonemorphogeneticprotein (rhBMP) should not be routinely used in any type of anterior cervical...
Growth differentiation factor 2 (GDF2) also known as bonemorphogeneticprotein (BMP)-9 is a protein that in humans is encoded by the GDF2 gene. GDF2 belongs...
conditions Any condition that causes instability of the spine Bonemorphogeneticprotein (rhBMP) should not be routinely used in any type of anterior cervical...
K, Keduka E, Endo T (February 2010). "M-Ras is activated by bonemorphogeneticprotein-2 and participates in osteoblastic determination, differentiation...