BMPR1B information

BMPR1B
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3MDY
Identifiers
Aliases	BMPR1B, ALK-6, ALK6, CDw293, AMDD, BDA1D, BDA2, bone morphogenetic protein receptor type 1B, AMD3
External IDs	OMIM: 603248 MGI: 107191 HomoloGene: 20322 GeneCards: BMPR1B
Gene location (Human)
Chr.	Chromosome 4 (human)
End	95,158,448 bp
Gene location (Mouse)
Chr.	Chromosome 3 (mouse)
End	141,875,186 bp
RNA expression pattern
	Top expressed in
	Achilles tendon; ; bronchial epithelial cell; ; seminal vesicula; ; entorhinal cortex; ; renal medulla; ; trigeminal ganglion; ; right uterine tube; ; external globus pallidus; ; internal globus pallidus; ; Brodmann area 23;
	Top expressed in
	cumulus cell; ; secondary oocyte; ; prostate; ; stria vascularis; ; ascending aorta; ; sclerotome; ; seminal vesicula; ; Region I of hippocampus proper; ; supraoptic nucleus; ; vein;
	More reference expression data
	n/a
Gene ontology
Molecular function	transferase activity; nucleotide binding; protein kinase activity; metal ion binding; kinase activity; protein serine/threonine kinase activity; transmembrane receptor protein serine/threonine kinase activity; transforming growth factor beta receptor activity, type I; protein binding; SMAD binding; ATP binding; transforming growth factor beta-activated receptor activity; growth factor binding;
Cellular component	integral component of membrane; HFE-transferrin receptor complex; membrane; receptor complex; plasma membrane; integral component of plasma membrane; neuronal cell body; dendrite;
Biological process	eye development; positive regulation of extrinsic apoptotic signaling pathway via death domain receptors; skeletal system development; cell differentiation; limb morphogenesis; ovarian cumulus expansion; chondrocyte differentiation; phosphorylation; positive regulation of bone mineralization; chondrocyte development; cellular response to BMP stimulus; BMP signaling pathway; protein phosphorylation; negative regulation of chondrocyte proliferation; cartilage development; positive regulation of osteoblast differentiation; transmembrane receptor protein serine/threonine kinase signaling pathway; retina development in camera-type eye; positive regulation of cartilage development; positive regulation of chondrocyte differentiation; positive regulation of cell differentiation; ovulation cycle; camera-type eye development; inflammatory response; dorsal/ventral pattern formation; endochondral bone morphogenesis; cartilage condensation; positive regulation of transcription by RNA polymerase II; proteoglycan biosynthetic process; retinal ganglion cell axon guidance; cellular response to growth factor stimulus; transforming growth factor beta receptor signaling pathway; pattern specification process;
	Sources:Amigo / QuickGO
Orthologs
	658
	12167
	ENSG00000138696
	ENSMUSG00000052430
	O00238
	P36898
	NM_001203; NM_001256792; NM_001256793; NM_001256794
NM_001277216; NM_001277217; NM_001277218; NM_001277220; NM_007560;
	NM_001355043
	NP_001194; NP_001243721; NP_001243722; NP_001243723
NP_001264145; NP_001264146; NP_001264147; NP_001264149; NP_031586;
	NP_001341972
	Wikidata
View/Edit Human	View/Edit Mouse

Bone morphogenetic protein receptor type-1B also known as CDw293 (cluster of differentiation w293) is a protein that in humans is encoded by the BMPR1B gene.^[5]^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000138696 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000052430 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ ten Dijke P, Yamashita H, Ichijo H, Franzén P, Laiho M, Miyazono K, Heldin CH (April 1994). "Characterization of type I receptors for transforming growth factor-beta and activin". Science. 264 (5155): 101–4. Bibcode:1994Sci...264..101T. doi:10.1126/science.8140412. PMID 8140412.
^ Ide H, Saito-Ohara F, Ohnami S, Osada Y, Ikeuchi T, Yoshida T, Terada M (1998). "Assignment of the BMPR1A and BMPR1B genes to human chromosome 10q22.3 and 4q23→q24 byin situ hybridization and radiation hybrid map ping". Cytogenet. Cell Genet. 81 (3–4): 285–6. doi:10.1159/000015048. PMID 9730621. S2CID 46751090.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000138696 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000052430 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid8140412-5] ten Dijke P, Yamashita H, Ichijo H, Franzén P, Laiho M, Miyazono K, Heldin CH (April 1994). "Characterization of type I receptors for transforming growth factor-beta and activin". Science. 264 (5155): 101–4. Bibcode:1994Sci...264..101T. doi:10.1126/science.8140412. PMID 8140412.

[pmid9730621-6] Ide H, Saito-Ohara F, Ohnami S, Osada Y, Ikeuchi T, Yoshida T, Terada M (1998). "Assignment of the BMPR1A and BMPR1B genes to human chromosome 10q22.3 and 4q23→q24 byin situ hybridization and radiation hybrid map ping". Cytogenet. Cell Genet. 81 (3–4): 285–6. doi:10.1159/000015048. PMID 9730621. S2CID 46751090.

BMPR1B information

and 21 Related for: BMPR1B information

BMPR1B

BMPR1A

Activin receptor

Coronary artery disease

Bone morphogenetic protein receptor

Transforming growth factor beta

MAP kinase kinase kinase kinase

Titin

TGF beta signaling pathway

List of human clusters of differentiation

MTOR

Brachydactyly

Repulsive guidance molecule A

MTORC1

Bone morphogenetic protein

MTOR inhibitors

GDF15

Protein kinase A

TGF beta 1

List of distinct cell types in the adult human body

Paracrine signaling