Group of three receptors to bone morphogenetic proteins
TKL Ser/Thr protein kinase family
Identifiers
Symbol
TKL
Membranome
1216
Bone morphogenetic protein receptors are serine-threonine kinase receptors. Transforming growth factor beta family proteins bind to these receptors.[1] There are four bone morphogenetic protein receptors:[2]
Bone morphogenetic protein receptor, type 1:
ACVR1
BMPR1A
BMPR1B
Bone morphogenetic protein receptor, type 2
^Miyazono K, Kamiya Y, Morikawa M (January 2010). "Bone morphogenetic protein receptors and signal transduction". Journal of Biochemistry. 147 (1): 35–51. doi:10.1093/jb/mvp148. PMID 19762341.
^Pasche B (December 2008). "The TGF Family. Cold Spring Harbor Monograph Series, Volume 50. Edited by Rik Derynck, Kohei Miyazono. Cold Spring Harbor (New York): Cold Spring Harbor Laboratory Press. xiv-1114 p.; ill.; index. 9780879697525. 2008". The Quarterly Review of Biology. 83 (4): 405–405. doi:10.1086/596254.
and 22 Related for: Bone morphogenetic protein receptor information
Bonemorphogeneticproteins (BMPs) are a group of growth factors also known as cytokines and as metabologens. Originally discovered by their ability to...
Bonemorphogeneticprotein 2 or BMP-2 belongs to the TGF-β superfamily of proteins. BMP-2 like other bonemorphogeneticproteins, plays an important role...
Bonemorphogeneticproteinreceptor type II or BMPR2 is a serine/threonine receptor kinase encoded by the BMPR2 gene. It binds bonemorphogenetic proteins...
Bonemorphogeneticprotein 7 or BMP7 (also known as osteogenic protein-1 or OP-1) is a protein that in humans is encoded by the BMP7 gene. The protein...
Bonemorphogeneticproteinreceptor type-1B also known as CDw293 (cluster of differentiation w293) is a protein that in humans is encoded by the BMPR1B...
Bonemorphogeneticprotein 6 is a protein that in humans is encoded by the BMP6 gene. The protein encoded by this gene is a member of the TGFβ superfamily...
Bonemorphogeneticprotein 3, also known as osteogenin, is a protein in humans that is encoded by the BMP3 gene. The protein encoded by this gene is a...
Bonemorphogeneticprotein 8B is a protein that in humans is encoded by the BMP8B gene. The protein encoded by this gene is a member of the TGF-β superfamily...
Bonemorphogeneticprotein 1, also known as BMP1, is a protein which in humans is encoded by the BMP1 gene. There are seven isoforms of the protein created...
Bonemorphogeneticprotein 10 (BMP10) is a protein that in humans is encoded by the BMP10 gene. BMP10 is a polypeptide belonging to the TGF-β superfamily...
Bonemorphogeneticprotein 5 is a protein that in humans is encoded by the BMP5 gene. The protein encoded by this gene is member of the TGFβ superfamily...
Bonemorphogeneticprotein 15 (BMP-15) is a protein that in humans is encoded by the BMP15 gene. It is involved in folliculogenesis, the process in which...
bind to the bonemorphogeneticproteinreceptor type II (BMPR2). Some of the proteins of the BMP family are BMP4 and BMP7. BMP4 promotes bone formation...
Bonemorphogeneticprotein 8A (BMP8A) is a protein that in humans is encoded by the BMP8A gene. BMP8A is a polypeptide member of the TGFβ superfamily of...
are also nerve cell survival factors. The BMPs bind to the bonemorphogeneticproteinreceptor type-2 (BMPR2). They are involved in a multitude of cellular...
Knaus P, Souchelnytskyi S (May 2004). "Proteins associated with type II bonemorphogeneticproteinreceptor (BMPR-II) and identified by two-dimensional...
protein kinase, as in bonemorphogeneticprotein Guanylate cyclase, as in atrial natriuretic factor receptor Intracellular receptors exist freely in the...
3-kinases may be activated by a G protein coupled receptor or receptor tyrosine kinase such as the insulin receptor. Once activated, PI 3-kinase phosphorylates...
Global Information