There are three known mammalian tachykinin receptors termed NK1, NK2 and NK3. All are members of the 7 transmembrane G-protein coupled receptor family and induce the activation of phospholipase C, producing inositol triphosphate (so called Gq-coupled).
Inhibitors of NK-1, known as NK-1 receptor antagonists, can be used as antiemetic agents, such as the drug aprepitant.[1]
^"Aprepitant". NICE. Retrieved 2020-05-10.
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three known mammalian tachykininreceptors termed NK1, NK2 and NK3. All are members of the 7 transmembrane G-protein coupled receptor family and induce the...
The tachykininreceptor 1 (TACR1) also known as neurokinin 1 receptor (NK1R) or substance P receptor (SPR) is a G protein coupled receptor found in the...
Tachykininreceptor 3, also known as TACR3, is a protein which in humans is encoded by the TACR3 gene. This gene belongs to a family of genes that function...
receptor is a protein that in humans is encoded by the TACR2 gene. This gene belongs to a family of genes that function as receptors for tachykinins....
tachykinin NK1 receptor, tachykinin NK2 receptor and tachykinin NK3 receptor. Biological research that identified the many functions of tachykinins sparked...
have been proposed as antipsychotics. Tachykinin peptides are also involved in inflammation, and tachykininreceptor antagonists have been researched for...
contraction. The endogenous receptor for substance P is neurokinin 1 receptor (NK1-receptor, NK1R). It belongs to the tachykininreceptor sub-family of GPCRs...
HH11, one of the Hamburger–Hamilton stages in chick development Tachykininreceptor 3 (HH11) Search for "hh11" or "hh-11" on Wikipedia. All pages with...
Chiwakata C, Brackmann B, Hunt N, Davidoff M, Schulze W, Ivell R (May 1991). "Tachykinin (substance-P) gene expression in Leydig cells of the human and mouse testis"...
NT-814) is an orally active small-molecule neurokinin/tachykinin NK1 receptor and NK3 receptor antagonist which is under development by Bayer, GlaxoSmithKline...
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neurotransmitter-encoding genes. Tachykinin proteins are cleaved into small, secreted peptides that activate members of a family of receptor proteins. The products...
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peptide receptor is a type of receptor which binds one or more signaling peptides or signaling proteins. An example is the tropomyosin receptor kinase...
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Neurokinin B (NKB) belongs in the family of tachykinin peptides. Neurokinin B is implicated in a variety of human functions and pathways such as the secretion...
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