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Tachykinin receptor 1 information


TACR1
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesTACR1, NK1R, NKIR, SPR, TAC1R, tachykinin receptor 1
External IDsOMIM: 162323; MGI: 98475; HomoloGene: 20288; GeneCards: TACR1; OMA:TACR1 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_015727
NM_001058

NM_009313

RefSeq (protein)

NP_001049
NP_056542

NP_033339

Location (UCSC)Chr 2: 75.05 – 75.2 MbChr 6: 82.38 – 82.54 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

The tachykinin receptor 1 (TACR1) also known as neurokinin 1 receptor (NK1R) or substance P receptor (SPR) is a G protein coupled receptor found in the central nervous system and peripheral nervous system. The endogenous ligand for this receptor is Substance P, although it has some affinity for other tachykinins. The protein is the product of the TACR1 gene.[5]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000115353 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000030043 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Takeda Y, Chou KB, Takeda J, Sachais BS, Krause JE (September 1991). "Molecular cloning, structural characterization and functional expression of the human substance P receptor". Biochemical and Biophysical Research Communications. 179 (3): 1232–1240. doi:10.1016/0006-291X(91)91704-G. PMID 1718267.

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