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Antiarrhythmic agent information


Antiarrhythmic agents, also known as cardiac dysrhythmia medications, are a class of drugs that are used to suppress abnormally fast rhythms (tachycardias), such as atrial fibrillation, supraventricular tachycardia and ventricular tachycardia.

Many attempts have been made to classify antiarrhythmic agents. Many of the antiarrhythmic agents have multiple modes of action, which makes any classification imprecise.

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Antiarrhythmic agent

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Antiarrhythmic agents, also known as cardiac dysrhythmia medications, are a class of drugs that are used to suppress abnormally fast rhythms (tachycardias)...

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Sodium channel blocker

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Vaughan Williams classification. Class I antiarrhythmic agents interfere with the (Na+) channel. Class I agents are grouped by their effect on the Na+ channel...

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Quinidine

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Quinidine is a class IA antiarrhythmic agent used to treat heart rhythm disturbances. It is a diastereomer of antimalarial agent quinine, originally derived...

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Lidocaine

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use in those allergic to tetracaine or benzocaine. Lidocaine is an antiarrhythmic medication of the class Ib type. This means it works by blocking sodium...

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Sparteine

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Sparteine is a class 1a antiarrhythmic agent and sodium channel blocker. It is an alkaloid and can be extracted from scotch broom. It is the predominant...

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Dofetilide

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Dofetilide is a class III antiarrhythmic agent. It is marketed under the trade name Tikosyn by Pfizer, and is available in the United States in capsules...

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Ibutilide

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Ibutilide is a Class III antiarrhythmic agent that is indicated for acute cardioconversion of atrial fibrillation and atrial flutter of a recent onset...

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Flecainide

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heart disease or ischemic heart disease. Flecainide is a class Ic antiarrhythmic agent. It works by decreasing the entry of sodium in heart cells, causing...

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Arrhythmia

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Medications for a fast heart rate may include beta blockers, or antiarrhythmic agents such as procainamide, which attempt to restore a normal heart rhythm...

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Sotalol

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β-adrenergic receptor blocker which has both class II and class III antiarrhythmic properties. Sotalol was first described in 1964 and came into medical...

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Potassium channel blocker

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treatment of cardiac arrhythmia are classified as class III antiarrhythmic agents. Class III agents predominantly block the potassium channels, thereby prolonging...

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Amiodarone

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Amiodarone is an antiarrhythmic medication used to treat and prevent a number of types of cardiac dysrhythmias. This includes ventricular tachycardia,...

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Tocainide

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Tocainide (Tonocard) is a class Ib antiarrhythmic agent. It is no longer sold in the United States. Tocainide is a lidocaine derivative, that undergoes...

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Adenosine

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adenosine on AV node-dependent SVTs, adenosine is considered a class V antiarrhythmic agent. When adenosine is used to cardiovert an abnormal rhythm, it is normal...

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Digitalis

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increase cardiac contractility (it is a positive inotrope) and as an antiarrhythmic agent to control the heart rate, particularly in the irregular (and often...

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Arrhythmogenic cardiomyopathy

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blocker and a class III antiarrhythmic agent, is the most effective antiarrhythmic agent in ACM. Other antiarrhythmic agents used include amiodarone and...

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Management of atrial fibrillation

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of antiarrhythmic agents. Recently, other approaches have been developed that promise to decrease or eliminate the need for antiarrhythmic agents. The...

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Pilsicainide

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Pilsicainide (INN) is an antiarrhythmic agent. It is marketed in Japan as サンリズム (Sunrythm). It was developed by Suntory Holdings Limited and first released...

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Propafenone

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economic and convenience reasons, some clinicians are starting certain antiarrhythmic agents in an outpatient setting for some patients. No consensus exists...

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Knoll Pharmaceuticals

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the United States and most other countries in 2010 Propafenone, an antiarrhythmic agent, marketed by Abbott.[citation needed] Isophan, a slightly modified...

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Pirolazamide

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Pirolazamide (SC-26,438) is an antiarrhythmic agent that was never marked. Triggle DJ (1996). Dictionary of Pharmacological Agents. Boca Raton: Chapman & Hall/CRC...

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Atrial flutter

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medications than atrial fibrillation. For example, although the class III antiarrhythmic agent ibutilide is an effective treatment for atrial flutter, rates of...

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Nifekalant

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Nifekalant (INN) is a class III antiarrhythmic agent approved in Japan for the treatment of arrhythmias and ventricular tachycardia. It has the brand name...

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Verapamil

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class-IV antiarrhythmic agents. Since calcium channels are especially concentrated in the sinoatrial and atrioventricular nodes, these agents can be used...

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Aprindine

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Aprindine is a Class 1b antiarrhythmic agent. "WHOCC - ATC/DDD Index". WHO Collaborating Centre for Drug Statistics Methodology. Retrieved 2018-03-01....

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Proarrhythmic agent

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Caffeine, cocaine, beta-adrenergic agonists Encainide, Lorcainide Antiarrhythmic agent Electrophysiology study Merritt H. Raitt; William E. Connor; Cynthia...

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Encainide

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Encainide (trade name Enkaid) is a class Ic antiarrhythmic agent. It is no longer used because of its frequent proarrhythmic side effects. Iferanserin...

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Torsades de pointes

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occurring in between 1% and 10% of patients who receive QT-prolonging antiarrhythmic drugs. Most episodes will revert spontaneously to a normal sinus rhythm...

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