Dexmedetomidine, sold under the trade name Precedex among others, is a drug used in humans for sedation.[3] Veterinarians use dexmedetomidine for similar purposes in treating cats, dogs, and horses.[6][7] It is also used in humans to treat acute agitation associated with schizophrenia or bipolar I or II disorder.[4]
Similar to clonidine, it is a sympatholytic drug that acts as an agonist of α2-adrenergic receptors in certain parts of the brain.[8] It was developed by Orion Pharma.
^"DEXMEDETOMIDINE FRESENIUS (Fresenius Kabi Australia Pty Ltd)". Department of Health and Aged Care. Archived from the original on 2023-03-18.
^Anvisa (2023-03-31). "RDC Nº 784 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial" [Collegiate Board Resolution No. 784 - Lists of Narcotic, Psychotropic, Precursor, and Other Substances under Special Control] (in Brazilian Portuguese). Diário Oficial da União (published 2023-04-04). Archived from the original on 2023-08-03. Retrieved 2023-08-16.
^ abc"Precedex- dexmedetomidine hydrochloride injection, solution". DailyMed. 2 March 2022. Archived from the original on 8 April 2022. Retrieved 8 April 2022.
^ ab"Igalmi- dexmedetomidine film". DailyMed. 14 December 2022. Retrieved 21 January 2023.
^Cite error: The named reference Weerink_2017 was invoked but never defined (see the help page).
^Marly-Voquer C, Schwarzwald CC, Bettschart-Wolfensberger R (January 2016). "The use of dexmedetomidine continuous rate infusion for horses undergoing transvenous electrical cardioversion--A case series". The Canadian Veterinary Journal. 57 (1): 70–75. PMC 4677613. PMID 26740702.
^"Dexdomitor". Archived from the original on 2013-09-27. Retrieved 2013-08-02.
^Cite error: The named reference Cormack2005 was invoked but never defined (see the help page).
Dexmedetomidine, sold under the trade name Precedex among others, is a drug used in humans for sedation. Veterinarians use dexmedetomidine for similar...
antagonist used for the reversal of the sedative and analgesic effects of dexmedetomidine and medetomidine in dogs. Its reversal effect works by competing with...
laryngospasm, but usually in the context of oropharyngeal manipulation. Dexmedetomidine is a more recent agent used in this process. It is an alpha-2 adrenergic...
atipamezole was used to reverse the effects of xylazine or the related drug dexmedetomidine in veterinary medicine, but this is not an approved medical treatment...
adrenergic agonist is dexmedetomidine, which is commonly used to provide a short term sedative effect (<24 hours). Dexmedetomidine and certain atypical...
Clonidine has also been suggested as a treatment for rare instances of dexmedetomidine withdrawal. Clonidine has some role in the treatment of spasticity...
surgery. The marketed product is a racemic mixture of two stereoisomers; dexmedetomidine is the isomer with more useful effects, and is now marketed as Dexdomitor...
through specific receptors) co-administration of Alpha2 agonists (dexmedetomidine) and/or opioid receptor agonists (morphine/fentanyl) can decrease the...
elderly, and brain protection. Bekker's work on expanding uses of dexmedetomidine, a new agent introduced in 1999 for sedation of critically ill patients...
clonidine is becoming increasingly popular with anesthesiologists. Dexmedetomidine and atypical antipsychotic agents are other premedications which are...
Thanvi A, Paliwal N, Karnawat R (2018). "Comparison of Esmolol and Dexmedetomidine for Suppression of Hemodynamic Response to Laryngoscopy and Endotracheal...
infusion of fentanyl, lidocaine, ketamine, dexmedetomidine, or the combination lidocaine-ketamine-dexmedetomidine after ovariohysterectomy in dogs". Veterinary...
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