Alpha-toxin, also known as alpha-hemolysin (Hla), is the major cytotoxic agent released by bacterium Staphylococcus aureus and the first identified member of the pore forming beta-barrel toxin family.[1] This toxin consists mostly of beta-sheets (68%) with only about 10% alpha-helices. The hly gene on the S. aureus chromosome encodes the 293 residue protein monomer, which forms heptameric units on the cellular membrane to form a complete beta-barrel pore. This structure allows the toxin to perform its major function, development of pores in the cellular membrane, eventually causing cell death.
Alpha-toxin, also known as alpha-hemolysin (Hla), is the major cytotoxic agent released by bacterium Staphylococcusaureus and the first identified member...
Staphylococcusaureus beta toxin is a toxin produced by Staphylococcusaureus. It is a form of sphingomyelinase called sphingomyelinase C. This enzyme...
Staphylococcusaureus is a Gram-positive spherically shaped bacterium, a member of the Bacillota, and is a usual member of the microbiota of the body...
Alphatoxin or alpha-toxin refers to several different protein toxins produced by bacteria, including: Staphylococcusaureusalphatoxin, a membrane-disrupting...
'Staphylococcusaureus delta toxin is a toxin produced by Staphylococcusaureus. It has a wide spectrum of cytolytic activity. It is among other toxins...
membrane. Secreted by Staphylococcusaureus, this toxin binds with the outer membrane, with subsequent oligomerization of the toxin monomers to form water-filled...
S. aureus) and TSLS (caused by S. pyogenes), disease progression stems from a superantigen toxin. The toxin in S. aureus infections is TSS Toxin-1, or...
paralysis. The toxin causes the disease botulism. The toxin is also used commercially for medical and cosmetic purposes. Botulinum toxin is an acetylcholine...
A toxin is a naturally occurring organic[dubious – discuss] poison produced by metabolic activities of living cells or organisms. They occur especially...
Tetanus toxin (TeNT) is an extremely potent neurotoxin produced by the vegetative cell of Clostridium tetani in anaerobic conditions, causing tetanus...
(SEB), is an enterotoxin produced by the gram-positive bacteria Staphylococcusaureus. It is a common cause of food poisoning, with severe diarrhea, nausea...
Shiga toxins are a family of related toxins with two major groups, Stx1 and Stx2, expressed by genes considered to be part of the genome of lambdoid prophages...
cause gangrene in calves with the presence of alphatoxin. Immune evasion proteins from Staphylococcusaureus have a significant conservation of protein...
Neurotoxins are toxins that are destructive to nerve tissue (causing neurotoxicity). Neurotoxins are an extensive class of exogenous chemical neurological...
polypeptide arranged into alpha-helices and beta-sheets. The three domains form a pronounced cleft that is the active site of RTA. Ricin toxin B chain (RTB) is...
United States, alongside norovirus, Salmonella, Campylobacter, and Staphylococcusaureus. However, it can sometimes be ingested and cause no harm. Infections...
Diphtheria toxin is an exotoxin secreted mainly by Corynebacterium diphtheriae but also by Corynebacterium ulcerans and Corynebacterium pseudotuberculosis...
pathogenicity and virulence of Staphylococcus schleiferi. However, similarities with infections caused by Staphylococcusaureus suggest that the two species...
Clostridium perfringens alphatoxin is a toxin produced by the bacterium Clostridium perfringens (C. perfringens) and is responsible for gas gangrene and...
antibody designed for the prevention of nosocomial pneumonia caused by Staphylococcusaureus. This drug was developed by MedImmune World Health Organization...
the area of hemolysis formed by the β-hemolysin elaborated from Staphylococcusaureus. Although the test is usually used to identify group B streptococcus...
five insecticidal toxins, termed α, β, γ, δ and ε-latroinsectotoxins, one vertebrate-specific neurotoxin, alpha-latrotoxin, and one toxin affecting crustaceans...
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