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Ricin information


Ricin
Ricin structure (PDB: 2AAI​). The A chain is shown in blue and the B chain in orange.
Identifiers
OrganismRicinus communis
SymbolRCOM_2159910
Entrez8287993
RefSeq (mRNA)XM_002534603.1
RefSeq (Prot)XP_002534649.1
UniProtP02879
Other data
EC number3.2.2.22
Chromosomewhole genome: 0 - 0.01 Mb
Search for
StructuresSwiss-model
DomainsInterPro
Ribosome-inactivating protein (Ricin A chain)
Identifiers
SymbolRIP
PfamPF00161
InterProIPR001574
PROSITEPDOC00248
SCOP21paf / SCOPe / SUPFAM
Available protein structures:
Pfam  structures / ECOD  
PDBRCSB PDB; PDBe; PDBj
PDBsumstructure summary
Ricin-type beta-trefoil lectin domain (Ricin B chain)
Identifiers
SymbolN/A
PfamPF00652
Pfam clanCL0066
PROSITEIPR000772
SCOP21abr / SCOPe / SUPFAM
CAZyCBM13
CDDcd00161
Available protein structures:
Pfam  structures / ECOD  
PDBRCSB PDB; PDBe; PDBj
PDBsumstructure summary

Ricin (/ˈrsɪn/ RY-sin) is a lectin (a carbohydrate-binding protein) and a highly potent toxin produced in the seeds of the castor oil plant, Ricinus communis. The median lethal dose (LD50) of ricin for mice is around 22 micrograms per kilogram of body weight via intraperitoneal injection. Oral exposure to ricin is far less toxic. An estimated lethal oral dose in humans is approximately one milligram per kilogram of body weight.[1]

Ricin is a toxalbumin and was first described by Peter Hermann Stillmark, the founder of lectinology. Ricin is chemically similar to robin.

  1. ^ "Ricin (from Ricinus communis) as undesirable substances in animal feed-Scientific Opinion of the Panel on Contaminants in the Food Chain". EFSA Journal. 6 (9). European Food Safety Authority: 726. September 2008. doi:10.2903/j.efsa.2008.726.

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Ricin

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Ricin (/ˈraɪsɪn/ RY-sin) is a lectin (a carbohydrate-binding protein) and a highly potent toxin produced in the seeds of the castor oil plant, Ricinus...

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2003 ricin letters

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The 2003 ricin letters were two ricin-laden letters found on two occasions between October and November 2003. One letter was mailed to the White House...

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List of incidents involving ricin

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This is a list of incidents involving the poison ricin. The incidents are predominantly attempts to use the poison for attacks, rather than accidents...

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Shannon Richardson

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and film roles, including The Walking Dead, but is best known for sending ricin-laced letters to U.S. President Barack Obama and New York City mayor Michael...

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Pankisi Gorge crisis

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preparing ricin and other chemical weapons. Colin Powell and others trumpeted the arrests as proof of the threat posed by the Zarqawi-Chechen-Pankisi ricin network...

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April 2013 ricin letters

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On April 15, 2013, an envelope that preliminarily tested positive for ricin, a highly toxic protein, was intercepted at the US Capitol's off-site mail...

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Security incidents involving Donald Trump

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"Canadian woman accused of mailing ricin to Trump, Valley officials indicted". wric.com. "Pascale Ferrier: White House ricin package suspect in court". BBC...

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Bulgarian umbrella

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hidden pneumatic mechanism which injects a small poisonous pellet containing ricin. It has a hollowed stalk in which the pellet neatly sits. Such an umbrella...

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Ricinus

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that is rich in triglycerides, mainly ricinolein. The seed also contains ricin, a highly potent water-soluble toxin, which is also present in lower concentrations...

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Georgi Markov

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a London street via a micro-engineered pellet that might have contained ricin. Contemporary newspaper accounts reported that he had been stabbed in the...

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Wood Green ricin plot

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The Wood Green ricin plot was an alleged bioterrorism plot to attack the London Underground with ricin poison. The Metropolitan Police Service arrested...

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Abrin

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when given to mice intravenously (approximately 3.86 times more toxic than ricin, being 2.7 micrograms per kilogram). The median toxic dose for humans ranges...

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Anthrax

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California medfly attack 2001 anthrax attacks Wood Green ricin plot 2003 ricin letters 2013 ricin letters Prevention and response Australia Group Caribbean...

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Jesse Pinkman

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ricin, which Jesse hides in a cigarette. Later on, when Gus is meeting with members of the cartel, Jesse considers spiking Gus' coffee with the ricin...

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Immunology

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to the poisons ricin and abrin. After feeding them with small but increasing dosages of ricin he ascertained that they had become "ricin-proof". Ehrlich...

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List of bioterrorist incidents

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"Envelope tests positive for ricin at Washington mail facility". CNN. Retrieved April 27, 2013. "Dutschke arrested in ricin case". WTVA. April 27, 2013...

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Peter Hermann Stillmark

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Über Ricin, ein giftiges Ferment aus den Samen von Ricinus comm. L. und einigen anderen Euphorbiaceen, which is a description of the isolation of ricin, a...

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Biological agent

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California medfly attack 2001 anthrax attacks Wood Green ricin plot 2003 ricin letters 2013 ricin letters Prevention and response Australia Group Caribbean...

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Centers for Disease Control and Prevention

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California medfly attack 2001 anthrax attacks Wood Green ricin plot 2003 ricin letters 2013 ricin letters Prevention and response Australia Group Caribbean...

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September 11 attacks

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invasion of Afghanistan 2001 Alleged Prague connection 2001 Iraq Resolution 2002 Wood Green ricin plot 2003 Colin Powell's UN presentation 2003 v t e...

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Half Measures

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Combo's killers work for Gus Fring. Jesse tells Walt and asks him to make ricin to exact revenge. Although Walt appears troubled by the gang's use of children...

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Debora Green

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home and killed two of her children, and to poisoning her husband with ricin with the intention of causing his death. The case was sensational, and covered...

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The Interview

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and diarrhea from the ricin poisoning, accidentally shooting Yu before dying. A guilt-ridden Skylark discards one of the ricin strips the next morning...

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Toxalbumin

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Croton gratissimus and Ricinus communis. Typical toxalbumins are abrin and ricin.[self-published source?] Ingestion of seed containing toxalbumins is not...

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Ma Anand Sheela

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California medfly attack 2001 anthrax attacks Wood Green ricin plot 2003 ricin letters 2013 ricin letters Prevention and response Australia Group Caribbean...

Word Count : 2084

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