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Surfac_D-trimer
Crystal structure of the trimeric neck and carbohydrate recognition domain of human surfactant protein D in complex with myoinositol
Identifiers
Symbol
Surfac_D-trimer
Pfam
PF09006
InterPro
IPR015097
Available protein structures:
Pfam
structures / ECOD
PDB
RCSB PDB; PDBe; PDBj
PDBsum
structure summary
In molecular biology, Pulmonary surfactant protein D (SP-D) is a protein domain predominantly found in lung surfactant. This protein plays a special role; its primary task is to act as a defence protein against any pathogens that may invade the lung. It also plays a role in lubricating the lung and preventing it from collapse. It has an interesting structure as it forms a triple-helical parallel coiled coil, helps the protein to fold into a trimer.[1]
^Kovacs H, O'Ddonoghue SI, Hoppe HJ, Comfort D, Reid KB, Campbell D, Nilges M (October 2002). "Solution structure of the coiled-coil trimerization domain from lung surfactant protein D". Journal of Biomolecular NMR. 24 (2): 89–102. doi:10.1023/A:1020980006628. PMID 12495025. S2CID 36593945.
and 30 Related for: Pulmonary surfactant protein D information
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([pref. protein]; -pathy [suff. disease]; proteinopathies pl.; proteinopathic adj), or proteopathy, protein conformational disorder, or protein misfolding...
Dipalmitoylphosphatidylcholine (lecithin) is a major component of the pulmonarysurfactant, and is often used in the lecithin–sphingomyelin ratio to calculate...
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