respiratory gaseous exchange by respiratory system
sphingolipid metabolic process
lipid metabolism
positive regulation of catalytic activity
Sources:Amigo / QuickGO
Orthologs
Species
Human
Mouse
Entrez
6439
20388
Ensembl
ENSG00000168878
ENSMUSG00000056370
UniProt
P07988
P50405
RefSeq (mRNA)
NM_000542 NM_198843 NM_001367281
NM_001282071 NM_147779
RefSeq (protein)
NP_000533 NP_942140 NP_001354210
NP_001269000 NP_680088
Location (UCSC)
Chr 2: 85.66 – 85.67 Mb
Chr 6: 72.28 – 72.29 Mb
PubMed search
[3]
[4]
Wikidata
View/Edit Human
View/Edit Mouse
Surfactant protein B is an essential lipid-associated protein found in pulmonary surfactant. Without it, the lung would not be able to inflate after a deep breath out.[5] It rearranges lipid molecules in the fluid lining the lung so that tiny air sacs in the lung, called alveoli, can more easily inflate.[6]
^ abcGRCh38: Ensembl release 89: ENSG00000168878 – Ensembl, May 2017
^ abcGRCm38: Ensembl release 89: ENSMUSG00000056370 – Ensembl, May 2017
^"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^Wert SE, Whitsett JA, Nogee LM (2009). "Genetic disorders of surfactant dysfunction". Pediatric and Developmental Pathology. 12 (4): 253–74. doi:10.2350/09-01-0586.1. PMC 2987676. PMID 19220077.
^Hawgood S, Derrick M, Poulain F (Nov 1998). "Structure and properties of surfactant protein B". Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1408 (2–3): 150–60. doi:10.1016/S0925-4439(98)00064-7. PMID 9813296.
and 28 Related for: Surfactant protein B information
SurfactantproteinB is an essential lipid-associated protein found in pulmonary surfactant. Without it, the lung would not be able to inflate after a...
Pulmonary surfactant is a surface-active complex of phospholipids and proteins formed by type II alveolar cells. The proteins and lipids that make up...
Surfactantprotein A is an innate immune system collectin. It is water-soluble and has collagen-like domains similar to SP-D. It is part of the innate...
Surfactantprotein D, also known as SP-D, is a lung surfactantprotein part of the collagenous family of lectins called collectin. In humans, SP-D is encoded...
Surfactantprotein C (SP-C), is one of the pulmonary surfactantproteins. In humans this is encoded by the SFTPC gene. It is a membrane protein. SFTPC...
Surfactants are chemical compounds that decrease the surface tension or interfacial tension between two liquids, a liquid and a gas, or a liquid and a...
alveolus integrity. SP-B and SP-C are the two hydrophobic surfactantproteins that participate in its physical functions; these proteins are encoded by SFTPB...
TA (January 2021). "Mechanism of Lamellar Body Formation by Lung SurfactantProteinB". Mol Cell. 81 (1): 49–66.e8. doi:10.1016/j.molcel.2020.10.042. PMC 7797001...
contains 80 mg of surfactant (extract) that includes 76 mg of phospholipids and 1 mg of protein of which 0.2 mg is surfactantproteinB (SP-B). Depending on...
Surfactantprotein A1 (SP-A1), also known as Pulmonary surfactant-associated protein A1 (PSP-A) is a protein that in humans is encoded by the SFTPA1 gene...
Surfactantprotein A2 (SP-A2), also known as Pulmonary surfactant-associated protein A2 (PSP-A2) is a protein that in humans is encoded by the SFTPA2...
and can result from a genetic problem with the production of surfactant-associated proteins. IRDS affects about 1% of newborns and is the leading cause...
S, Derrick M, Poulain F (Nov 1998). "Structure and properties of surfactantproteinB". Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease...
reduce the surface tension of the alveolar liquid, the proteins and other lipids in the surfactant further facilitate the adsorption of oxygen into the...
Inovirus (filamentous phage) major coat protein Pilin Pulmonary surfactant-associated protein Monoamine oxidases A and B Fatty acid amide hydrolase Cytochrome...
its molecular structure. Working with John Heuser, she examined a surfactantprotein, SP-D, and researched the interactions between SP-D and influenza...
(saposin-like protein) family along with amoebapore, granulysin, acid sphingomyelinase, surfactantproteinB, and the 4 sphingolipid activator proteins (saposins)...
Galaxy Surfactants Ltd. is an Indian multinational specialty chemical company based in Mumbai, Maharashtra, India. It is a manufacturer of surfactants and...
Amyloids are aggregates of proteins characterised by a fibrillar morphology of typically 7–13 nm in diameter, a β-sheet secondary structure (known as cross-β)...
surfactant, with a C12 (dodecyl) alkyl tail. It is one of the most frequently-used surfactants of this type. Like other amine oxide–based surfactants...
"Involvement of napsin A in the C- and N-terminal processing of surfactantproteinB in type-II pneumocytes of the human lung". J. Biol. Chem. 278 (49):...
Many adjuvants also contain or act directly as: surfactants which promote concentration of protein antigens molecules over a large surface area, and...
McNeely, T B; J D Coonrod (July 1994). "Aggregation and opsonization of type A but not type B Hemophilus influenzae by surfactantprotein A". American...
A detergent is a surfactant or a mixture of surfactants with cleansing properties when in dilute solutions. There are a large variety of detergents, a...
surfactant-type micelles in a sense that the hydrophilic parts reside at the surface and they are spherical. However, in sharp contrast to surfactant...
evaporative cooling. Further, it is speculated that the presence of a surfactantprotein in the saliva of ruminant animals (e.g., cow, horse, sheep) may assist...
separate the protein, α-lactalbumin, from a whey protein solution. pH is an important factor in foaming because it will determine if a surfactant will be able...
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