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Surfactant protein C information


SFTPC
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesSFTPC, BRICD6, PSP-C, SFTP2, SMDP2, SP-C, surfactant protein C, SP5
External IDsOMIM: 178620; MGI: 109517; HomoloGene: 2271; GeneCards: SFTPC; OMA:SFTPC - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_011359

RefSeq (protein)

NP_035489

Location (UCSC)Chr 8: 22.16 – 22.16 MbChr 14: 70.76 – 70.76 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Surfactant protein C (SP-C), is one of the pulmonary surfactant proteins. In humans this is encoded by the SFTPC gene.[5][6][7]

It is a membrane protein.

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000168484 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000022097 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Keller A, Eistetter HR, Voss T, Schäfer KP (July 1991). "The pulmonary surfactant protein C (SP-C) precursor is a type II transmembrane protein". The Biochemical Journal. 277 ( Pt 2) (Pt 2): 493–9. doi:10.1042/bj2770493. PMC 1151261. PMID 1859376.
  6. ^ Johansson H, Nordling K, Weaver TE, Johansson J (July 2006). "The Brichos domain-containing C-terminal part of pro-surfactant protein C binds to an unfolded poly-val transmembrane segment". The Journal of Biological Chemistry. 281 (30): 21032–9. doi:10.1074/jbc.M603001200. PMID 16709565.
  7. ^ "Entrez Gene: SFTPC surfactant, pulmonary-associated protein C".

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molecular biology, Pulmonary surfactant protein D (SP-D) is a protein domain predominantly found in lung surfactant. This protein plays a special role; its...

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transcription factor 1; translocated to, 1 (cyclin D-related) SFTPC: surfactant protein C SLC20A2: Sodium-dependent phosphate transporter 2 SLURP1: secreted...

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S, Derrick M, Poulain F (Nov 1998). "Structure and properties of surfactant protein B". Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease...

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Nguyen V, Russo SJ, Muniswamy M, Beers MF (June 2005). "A surfactant protein C precursor protein BRICHOS domain mutation causes endoplasmic reticulum stress...

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