respiratory gaseous exchange by respiratory system
toll-like receptor signaling pathway
surfactant homeostasis
positive regulation of phagocytosis
developmental process
Sources:Amigo / QuickGO
Orthologs
Species
Human
Mouse
Entrez
729238
20387
Ensembl
ENSG00000185303
ENSMUSG00000021789
UniProt
Q8IWL1
P35242 Q9CQI1
RefSeq (mRNA)
NM_001098668 NM_001320813 NM_001320814
NM_023134
RefSeq (protein)
NP_001092138 NP_001307742 NP_001307743
NP_075623
Location (UCSC)
Chr 10: 79.56 – 79.56 Mb
Chr 14: 40.85 – 40.86 Mb
PubMed search
[3]
[4]
Wikidata
View/Edit Human
View/Edit Mouse
Surfactant protein A2(SP-A2), also known as Pulmonary surfactant-associated protein A2(PSP-A2) is a protein that in humans is encoded by the SFTPA2 gene.[5][6]
^ abcGRCh38: Ensembl release 89: ENSG00000185303 – Ensembl, May 2017
^ abcGRCm38: Ensembl release 89: ENSMUSG00000021789 – Ensembl, May 2017
^"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Entrez Gene: SFTPA2 surfactant, pulmonary-associated protein A2".
^Silveyra P, Floros J (December 2013). "Genetic complexity of the human surfactant-associated proteins SP-A1 and SP-A2". Gene. 531 (2): 126–32. doi:10.1016/j.gene.2012.09.111. PMC 3570704. PMID 23069847.
and 26 Related for: Surfactant protein A2 information
Surfactantprotein A1 (SP-A1), also known as Pulmonary surfactant-associated protein A1 (PSP-A) is a protein that in humans is encoded by the SFTPA1 gene...
Surfactantprotein B is an essential lipid-associated protein found in pulmonary surfactant. Without it, the lung would not be able to inflate after a...
and can result from a genetic problem with the production of surfactant-associated proteins. IRDS affects about 1% of newborns and is the leading cause...
which have more A2 cows), the United States, Australia, and New Zealand. Interest in the distinction between A1 and A2 beta-casein proteins began in the...
2015). "14-3-3 isoforms bind directly exon B of the 5'-UTR of human surfactantproteinA2 mRNA". American Journal of Physiology. Lung Cellular and Molecular...
phospholipase A2 (PLA2), a potent proinflammatory enzyme, which may directly (or through the stimulation of arachidonic acid) lead to surfactant dysfunction...
"casein micelles": aggregates of several thousand protein molecules with superficial resemblance to a surfactant micelle, bonded with the help of nanometer-scale...
food fats, though minor in comparison to triglycerides. DAGs can act as surfactants and are commonly used as emulsifiers in processed foods. DAG-enriched...
structures, depending on hydration and temperature. This results in a type of surfactant that usually is classified as amphipathic. Lecithin is sold as a food...
their role in promoting maturation of the lung and production of the surfactant necessary for extrauterine lung function. Mice with homozygous disruptions...
Endothelial PAS domain-containing protein 1 (EPAS1, also known as hypoxia-inducible factor-2alpha (HIF-2α)) is a protein that is encoded by the EPAS1 gene...
activate phospholipase A2 and is found, along with CK, to be a mediator of arachidonic acid released in cells in response to a protein called interleukin-1β...
JA, Yan C (January 2000). "Retinoic acid stimulation of the human surfactantprotein B promoter is thyroid transcription factor 1 site-dependent". The...
inorganic salts. Bilirubin is its major pigment. Bile acts partly as a surfactant which lowers the surface tension between either two liquids or a solid...
system (see complement proteins section) Collectins Mannan-binding lectin (MBL) Surfactantprotein A (SP-A) Surfactantprotein D (SP-D) CL-L1 CL-P1 CL-K1...
that there was roughly 20000-25000, as most DNA does not code for any protein but rather serve other more administrative functions or leftovers from...
Whitsett JA, et al. (1996). "Purification of a cell-surface receptor for surfactantprotein A." J. Biol. Chem. 271 (27): 16375–83. doi:10.1074/jbc.271.27.16375...
Vascular endothelial growth factor A (VEGF-A) is a protein that in humans is encoded by the VEGFA gene. This gene is a member of the platelet-derived...
acid group of linoleic acid yields linoleyl alcohol. Linoleic acid is a surfactant with a critical micelle concentration of 1.5 x 10−4 M @ pH 7.5.[citation...
hypochlorite washes Didecyldimethylammonium chloride Hand washing (see also Surfactants) Hand washing is a mechanical process of removing germs and viruses,...
extracellular space. Collectins (e.g. mannose-binding lectin and surfactantprotein A) bind the altered surface sugars on apoptotic cell and enable easier...
sporadic IPF. Genetic associations include mutations in pulmonary surfactantproteins A1, A2, C (SFTPA1, SFTPA2B) and mucin (MUC5B). A remarkable aspect of...
smooth muscle contraction. In addition, lysophospholipids can be found as surfactants in food techniques and cosmetics, and can be used in drug delivery. Since...
applying Agri-fos as a spray, it must be combined with an organosilicate surfactant, Pentra-bark, to enable the product to adhere to the tree trunk long enough...
Global Information
