Milacemide information

Milacemide
Names
	IUPAC name N2-Pentylglycinamide
	Systematic IUPAC name 2-(Pentylamino)acetamide
Identifiers
CAS Number	76990-56-2 ;
3D model (JSmol)	Interactive image;
ChEMBL	ChEMBL75838 ;
ChemSpider	48376 ;
MeSH	milacemide
PubChem CID	53569;
UNII	0HXT24RECU ;
CompTox Dashboard (EPA)	DTXSID10227786 ;
	InChI InChI=1S/C7H16N2O/c1-2-3-4-5-9-6-7(8)10/h9H,2-6H2,1H3,(H2,8,10) Key: GJNNXIYZWIZFRH-UHFFFAOYSA-N ;
	SMILES CCCCCNCC(N)=O;
Properties
Chemical formula	C7H16N2O
Molar mass	144.218 g·mol−1
log P	0.754
Related compounds
Related compounds	Tricine
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

Milacemide (INN)^[2] is an MAO-B inhibitor and glycine prodrug.^[3] It has been studied for its effects on human memory and as a potential treatment for the symptoms of Alzheimer's disease.^[4] Early clinical trials did not show positive results however,^[3] and the drug is now abandoned and it is sold as a nonprescription drug or supplement. While milacemide is not an amino-acid, it acts similarly to glycine in the brain.^[5]

^ "milacemide - Compound Summary". PubChem Compound. USA: National Center for Biotechnology Information. 8 August 2005. Identifiers and Related Records. Retrieved 9 January 2012.
^ "International Nonproprietary Names for Pharmaceutical Substances. Supplement to WHO Chronicle, 1983, Vol. 37, No. 6 (December). Recommended International Nonproprietary Names (Rec. INN): List 23" (PDF). World Health Organization. p. 6. Retrieved 8 January 2016.
^ ^a ^b Dysken, MW; Mendels, J; LeWitt, P; Reisberg, B; Pomara, N; Wood, J; Skare, S; Fakouhi, JD; Herting, RL (May 1992). "Milacemide: a placebo-controlled study in senile dementia of the Alzheimer type". Journal of the American Geriatrics Society. 40 (5): 503–6. doi:10.1111/j.1532-5415.1992.tb02019.x. PMID 1634705. S2CID 34816755.
^ Harris, Carol Turkington ; foreword by Joseph R. (2002). The encyclopedia of the brain and brain disorders (2nd ed.). New York, NY: Facts on File. ISBN 0-8160-4774-X. Archived from the original on 2014-03-03. Retrieved 2017-09-10.{{cite book}}: CS1 maint: multiple names: authors list (link)
^ Theodore I. Lidsky and Jay S. Schneider Phd, Brain Candy (2001). Brain Candy. New York, United States Of America: Simon & Schuster. ISBN 9780743218436.

[1] "milacemide - Compound Summary". PubChem Compound. USA: National Center for Biotechnology Information. 8 August 2005. Identifiers and Related Records. Retrieved 9 January 2012.

[2] "International Nonproprietary Names for Pharmaceutical Substances. Supplement to WHO Chronicle, 1983, Vol. 37, No. 6 (December). Recommended International Nonproprietary Names (Rec. INN): List 23" (PDF). World Health Organization. p. 6. Retrieved 8 January 2016.

[Dysken-3] Dysken, MW; Mendels, J; LeWitt, P; Reisberg, B; Pomara, N; Wood, J; Skare, S; Fakouhi, JD; Herting, RL (May 1992). "Milacemide: a placebo-controlled study in senile dementia of the Alzheimer type". Journal of the American Geriatrics Society. 40 (5): 503–6. doi:10.1111/j.1532-5415.1992.tb02019.x. PMID 1634705. S2CID 34816755.

[4] Harris, Carol Turkington ; foreword by Joseph R. (2002). The encyclopedia of the brain and brain disorders (2nd ed.). New York, NY: Facts on File. ISBN 0-8160-4774-X. Archived from the original on 2014-03-03. Retrieved 2017-09-10.{{cite book}}: CS1 maint: multiple names: authors list (link)

[5] Theodore I. Lidsky and Jay S. Schneider Phd, Brain Candy (2001). Brain Candy. New York, United States Of America: Simon & Schuster. ISBN 9780743218436.

Milacemide information

and 29 Related for: Milacemide information

Milacemide

Ketamine

Magnesium

Zinc

Pentobarbital

Morphine

Diethyl ether

Codeine

Hydrochlorothiazide

Furosemide

Glycine receptor agonist

Phencyclidine

Barbiturate

Diphenhydramine

Tramadol

Strychnine

Haloperidol

Saffron

Chloroform

Nitrous oxide

Sodium thiopental

Topiramate

Toluene

Monoamine oxidase inhibitor

Diazepam

Ibogaine

Chloral hydrate

Taurine

Glycine

Names

IUPAC name N²-Pentylglycinamide
Systematic IUPAC name 2-(Pentylamino)acetamide^[1]
Identifiers
CAS Number	76990-56-2^Y
3D model (JSmol)	Interactive image
ChEMBL	ChEMBL75838^Y
ChemSpider	48376^Y
MeSH	milacemide
PubChem CID	53569
UNII	0HXT24RECU^Y
CompTox Dashboard (EPA)	DTXSID10227786
InChI InChI=1S/C7H16N2O/c1-2-3-4-5-9-6-7(8)10/h9H,2-6H2,1H3,(H2,8,10)^Y Key: GJNNXIYZWIZFRH-UHFFFAOYSA-N^Y
SMILES CCCCCNCC(N)=O
Properties
Chemical formula	C₇H₁₆N₂O
Molar mass	144.218 g·mol⁻¹
log P	0.754
Related compounds
Related compounds	Tricine
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references