Biological functions of nitric oxide are roles that nitric oxide plays within biology.
Nitric oxide (nitrogen monoxide) is a molecule and chemical compound with chemical formula of NO. In mammals including humans, nitric oxide is a signaling molecule involved in several physiological and pathological processes.[1] It is a powerful vasodilator with a half-life of a few seconds in the blood. Standard pharmaceuticals such as nitroglycerine and amyl nitrite are precursors to nitric oxide. Low levels of nitric oxide production are typically due to ischemic damage in the liver.
As a consequence of its importance in neuroscience, physiology, and immunology, nitric oxide was proclaimed "Molecule of the Year" in 1992.[2] Research into its function led to the 1998 Nobel Prize for elucidating the role of nitric oxide as a cardiovascular signalling molecule.
^Hou YC, Janczuk A, Wang PG (June 1999). "Current trends in the development of nitric oxide donors". Current Pharmaceutical Design. 5 (6): 417–441. doi:10.2174/138161280506230110111042. PMID 10390607.
^Culotta E, Koshland DE (December 1992). "NO news is good news". Science. 258 (5090): 1862–1865. Bibcode:1992Sci...258.1862C. doi:10.1126/science.1361684. PMID 1361684.
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family of antimicrobial molecules derived from nitricoxide (•NO) and superoxide (O2•−) produced via the enzymatic activity of inducible nitricoxide synthase...
guanidine group in arginine is the precursor for the biosynthesis of nitricoxide. Like all amino acids, it is a white, water-soluble solid. The one-letter...
Oxidative stress reflects an imbalance between the systemic manifestation of reactive oxygen species and a biological system's ability to readily detoxify...
tetrodotoxin. Some substances such as nitricoxide and glutamate are in fact essential for proper functionof the body and only exert neurotoxic effects...
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sulfate ([NH3OH]+[HSO4]−), by the hydrogenation ofnitricoxide over platinum catalysts in the presence of sulfuric acid. 2 NO + 3 H2 + 2 H2SO4 → 2 [NH3OH]+[HSO4]−...
number of other biologically important hemoproteins such as myoglobin, cytochromes, catalases, heme peroxidase, and endothelial nitricoxide synthase...
on a need to meet distinct characterization criteria. Currently, only nitricoxide, carbon monoxide, and hydrogen sulfide are accepted as gasotransmitters...
some cells of the mammalian body and has a number ofbiological signaling functions. Only two other such gases are currently known: nitricoxide (NO) and...
molecular targets, notably: neurotransmitter systems, ion channels, nitricoxide (NO) synthesis and polyamine metabolism and this provides bases for further...
into nitricoxide. Many notable nitrogen-containing drugs, such as the natural caffeine and morphine or the synthetic amphetamines, act on receptors of animal...
biological processes, such as Ca2+ influx by glutamatergic N-methyl-D-aspartate receptor (NMDA receptor), which has been associated with nitricoxide...
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