Drug that causes vasodilation by releasing nitric oxide
Nitrovasodilator
Drug class
Nitric oxide
Class identifiers
Use
Angina pectoris, vasodilation
ATC code
C01DA
Biological target
Guanylate cyclase
Legal status
In Wikidata
A nitrovasodilator is a pharmaceutical agent that causes vasodilation (widening of blood vessels) by donation of nitric oxide (NO),[1] and is mostly used for the treatment and prevention of angina pectoris.
This group of drugs includes nitrates (esters of nitric acid), which are reduced to NO in the body, as well as some other substances.
^Brandes RP, Kim D, Schmitz-Winnenthal FH, et al. (January 2000). "Increased nitrovasodilator sensitivity in endothelial nitric oxide synthase knockout mice: role of soluble guanylyl cyclase". Hypertension. 35 (1 Pt 2): 231–6. doi:10.1161/01.hyp.35.1.231. PMID 10642303.
A nitrovasodilator is a pharmaceutical agent that causes vasodilation (widening of blood vessels) by donation of nitric oxide (NO), and is mostly used...
It is primarily a peripheral arterial vasodilator, thus unlike the nitrovasodilators (nitroglycerin and nitroprusside), cardiac preload is minimally affected...
in increasing calcium removal from the cytoplasm. prostacyclin cGMP-mediated (Nitrovasodilator) Through stimulation of protein kinase G. nitric oxide...
Propatylnitrate (propatyl nitrate) is a nitrovasodilator that is used as a medication against angina pectoris. Sandler, G. (1961). "Clinical Evaluation...
This class of drug, to which amyl nitrite also belongs, is known as nitrovasodilators. The two areas of concerns about the toxicity of nitrate are the following:...
and hearing loss. Tadalafil is not recommended in people taking nitrovasodilators such as nitroglycerin, as this may result in a serious drop in blood...
Doctor Who serial The Tenth Planet SNO-Cap (S-Nitrosocaptopril), a nitrovasodilator Snowcap, a large white area of coloration in horses from the coat patterns...
changes in the safety or efficacy of either agent. Combination with nitrovasodilators such as nitroglycerin and PETN is contraindicated because potentially...
suitable for surgical AVR. Any angina is treated with short-acting nitrovasodilators, beta-blockers and/or calcium blockers, although nitrates can drastically...
methylphenidate. Nitroglycerine (or glyceryl trinitrate) and other nitrovasodilators of the nitrate type demonstrates tachyphylaxis, requiring drug-free...
or other nitrovasodilators. Ergolines can antagonise the effects of molsidomine. Molsidomine belongs to the drug class of nitrovasodilators. It releases...
seen in mitral stenosis: Any angina is treated with short-acting nitrovasodilators, beta-blockers and/or calcium blockers Any hypertension is treated...
the source of oxidative stress in the vasculature. NO donor drugs (nitrovasodilators) have therefore been used for more than a century to treat coronary...
"Molecular basis of the synergistic inhibition of platelet function by nitrovasodilators and activators of adenylate cyclase: inhibition of cyclic AMP breakdown...
messenger cGMP and functions as the main receptor for nitric oxide and nitrovasodilator drugs. GUCY1B3 has been shown to interact with Heat shock protein 90kDa...
messenger cGMP and functions as the main receptor for nitric oxide and nitrovasodilator drugs. Mutations in this gene have been associated to cases of myocardial...
Global Information