Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N (what is YN ?)
Infobox references
Chemical compound
Thymidine triphosphate (TTP), also called deoxythymidine triphosphate (dTTP),[1]
is one of the four nucleoside triphosphates that are used in the in vivo synthesis of DNA. Unlike the other deoxyribonucleoside triphosphates, thymidine triphosphate does not always contain the "deoxy" prefix in its name.[2] The corresponding ribonucleoside triphosphate is called uridine triphosphate.
It can be used by DNA ligase to create overlapping "sticky ends" so that protruding ends of opened microbial plasmids may be closed up.
^
"Thymidine 5'-triphosphate (PAMDB000346)". University of Maryland, Baltimore. 2018-01-22. Archived from the original on 2023-10-29. Retrieved 2023-10-29.
^Coghill, Anne M.; Garson, Lorrin R., eds. (2006). The ACS style guide: effective communication of scientific information (3rd ed.). Washington, D.C.: American Chemical Society. p. 244. ISBN 978-0-8412-3999-9.
and 23 Related for: Thymidine triphosphate information
Thymidinetriphosphate (TTP), also called deoxythymidine triphosphate (dTTP), is one of the four nucleoside triphosphates that are used in the in vivo...
viral thymidine kinases. Thymidine kinase catalyzes the reaction: Thd + ATP → TMP + ADP where Thd is (deoxy)thymidine, ATP is adenosine triphosphate, TMP...
both UTP and ATP are energetically equal. The homologue in DNA is thymidinetriphosphate (TTP or dTTP). UTP also has a deoxyribose form (dUTP). UTP also...
HAT Medium (hypoxanthine-aminopterin-thymidine medium) is a selection medium for mammalian cell culture, which relies on the combination of aminopterin...
which nucleoside diphosphate kinase can phosphorylate into uridine triphosphate. Thymidine phosphorylase or pyrimidine-nucleoside phosphorylase adds 2-deoxy-alpha-D-ribose...
Thd + ATP → TMP + ADP where Thd is (deoxy)thymidine, ATP is adenosine 5’-triphosphate, TMP is (deoxy)thymidine 5’-phosphate and ADP is adenosine 5’-diphosphate...
the γ-DNA polymerase in some cell mitochondria, the depletion of thymidinetriphosphate, oxidative stress, reduction of intracellular L-carnitine or apoptosis...
blood disorder Tristetraprolin, a protein Thymidinetriphosphate, one of the four nucleoside triphosphates that are used in the in vivo synthesis of DNA...
and mammalian cells undergo cell death when they are starved of thymidinetriphosphate (dTTP), an essential precursor for DNA replication. This phenomenon...
kinase catalyzes production of thymidinetriphosphate, dTTP, which is used in DNA synthesis. Because of this, thymidine kinase activity is closely correlated...
The modified nucleotides (usually in a ratio of 1 aaUTP: 4 TTP (thymidinetriphosphate)) are added enzymatically in a low ratio to normal nucleotides,...
monophosphate form by viral thymidine kinase, which is more effective (3000 times) in phosphorylation of aciclovir than cellular thymidine kinase. Subsequently...
form uridine-triphosphate or UTP. UTP can be converted to CTP (cytidine-triphosphate) in a reaction catalyzed by CTP synthetase. Thymidine synthesis first...
cellular thymidine kinases phosphorylate the parent form significantly less rapidly than does the viral thymidine kinase, so the active triphosphate is present...
a nucleoside analog of thymidine. It is phosphorylated by cellular kinases into an active triphosphate. Stavudine triphosphate inhibits HIV's reverse...
ganciclovir triphosphate to concentrate in infected cells. Ganciclovir triphosphate is a competitive inhibitor of deoxyguanosine triphosphate (dGTP). It...
polymerase activity in low temperatures, use of modified deoxyribonucleotide triphosphates (dNTPs), and the physical addition of one of the essential reagents...
nucleoside thymidine. The active compound is brivudine 5'-triphosphate, which is formed in subsequent phosphorylations by viral (but not human) thymidine kinase...
nucleosides which make up nucleic acids, the others being adenosine, thymidine, cytidine and guanosine. The five nucleosides are commonly abbreviated...
nucleotidases break down nucleotides (such as the thymidine monophosphate) into nucleosides (such as thymidine) and phosphate. The nucleosides, in turn, are...
converted by viral thymidine kinase to aciclovir monophosphate, which is then converted by host cell kinases to aciclovir triphosphate (ACV-TP, also known...
unwinds the DNA and, re-ligates it again at the 3' phosphate group of the thymidine base. The vectors in commercially available TOPO kits have been added...
Bacchetti S, Graham FL (April 1977). "Transfer of the gene for thymidine kinase to thymidine kinase-deficient human cells by purified herpes simplex viral...