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Nucleoside information


deoxyadenosine
deoxyadenosine
adenosine
adenosine
Two corresponding nucleosides, the deoxyribonucleoside, deoxyadenosine, and the ribonucleoside, adenosine. The line-angle molecular representation implies carbon atoms at each angle, each with enough hydrogen atoms to fill its four-bond valency.

Nucleosides are glycosylamines that can be thought of as nucleotides without a phosphate group. A nucleoside consists simply of a nucleobase (also termed a nitrogenous base) and a five-carbon sugar (ribose or 2'-deoxyribose) whereas a nucleotide is composed of a nucleobase, a five-carbon sugar, and one or more phosphate groups. In a nucleoside, the anomeric carbon is linked through a glycosidic bond to the N9 of a purine or the N1 of a pyrimidine. Nucleotides are the molecular building blocks of DNA and RNA.

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Nucleoside

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Nucleosides are glycosylamines that can be thought of as nucleotides without a phosphate group. A nucleoside consists simply of a nucleobase (also termed...

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Nucleoside triphosphate

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A nucleoside triphosphate is a nucleoside containing a nitrogenous base bound to a 5-carbon sugar (either ribose or deoxyribose), with three phosphate...

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Arabinosyl nucleoside

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Arabinosyl nucleosides are derivatives of the nucleosides. They contain β-D-arabinofuranose, in contrast to most nucleosides which contain β-D-ribofuranose...

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Nucleotide

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fundamental, cellular level. They provide chemical energy—in the form of the nucleoside triphosphates, adenosine triphosphate (ATP), guanosine triphosphate (GTP)...

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Nucleoside analogue

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Nucleoside analogues are structural analogues of a nucleoside, which normally contain a nucleobase and a sugar. Nucleotide analogues are analogues of...

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Nucleoside phosphotransferase

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In enzymology, a nucleoside phosphotransferase (EC 2.7.1.77) is an enzyme that catalyzes the chemical reaction a nucleotide + a 2'-deoxynucleoside ⇌ {\displaystyle...

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Nucleoside deoxyribosyltransferase

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In enzymology, a nucleoside deoxyribosyltransferase (EC 2.4.2.6) is an enzyme that catalyzes the chemical reaction 2-deoxy-D-ribosyl-base1 + base2 ⇌ {\displaystyle...

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Nucleoside transporter

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Nucleoside transporters (NTs) are a group of membrane transport proteins which transport nucleoside substrates like adenosine across the membranes of...

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Pyrimidine

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showed how pyrimidine nucleosides can be synthesized from small molecules and ribose, driven solely by wet-dry cycles. Purine nucleosides can be synthesized...

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Synthesis of nucleosides

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Synthesis of nucleosides involves the coupling of a nucleophilic, heterocyclic base with an electrophilic sugar. The silyl-Hilbert-Johnson (or Vorbrüggen)...

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Purine nucleoside phosphorylase

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Purine nucleoside phosphorylase, PNP, PNPase or inosine phosphorylase (EC 2.4.2.1) is an enzyme that in humans is encoded by the NP gene. It catalyzes...

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Nucleoside phosphoramidite

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Nucleoside phosphoramidites are derivatives of natural or synthetic nucleosides. They are used to synthesize oligonucleotides, relatively short fragments...

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Nucleoside oxidase

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Nucleoside oxidase (EC 1.1.3.28) is an enzyme with systematic name nucleoside:oxygen 5'-oxidoreductase. This enzyme catalyses the following chemical reaction...

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Purine nucleosidase

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purine nucleoside + H2O ⇌ {\displaystyle \rightleftharpoons } D-ribose + a purine base Thus, the two substrates of this enzyme are purine nucleoside and...

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Concentrative nucleoside transporter

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Human concentrative nucleoside transporters include SLC28A1, SLC28A2 and SLC28A3 proteins. SLC28A2 is a purine-specific Na+-nucleoside cotransporter localised...

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Guanosine triphosphate

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Guanosine-5'-triphosphate (GTP) is a purine nucleoside triphosphate. It is one of the building blocks needed for the synthesis of RNA during the transcription...

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NS5B inhibitor

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inhibitors may be categorized into three classes—nucleoside active site inhibitors (NIs), non-nucleoside allosteric inhibitors, and pyrophosphate analogues...

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Cidofovir

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Cidofovir, brand name Vistide, is a topical or injectable antiviral medication primarily used as a treatment for cytomegalovirus (CMV) retinitis (an infection...

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Nucleoside ribosyltransferase

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In enzymology, a nucleoside ribosyltransferase (EC 2.4.2.5) is an enzyme that catalyzes the chemical reaction D-ribosyl-base1 + base2 ⇌ {\displaystyle...

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Ribosylpyrimidine nucleosidase

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nucleoside + H2O ⇌ {\displaystyle \rightleftharpoons } D-ribose + a pyrimidine base Thus, the two substrates of this enzyme are pyrimidine nucleoside...

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Equilibrative nucleoside transporter family

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Members of the Equilibrative Nucleoside Transporter (ENT) Family (TC# 2.A.57) are transport proteins that are specific to nucleosides and nucleobases, and are...

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Adenosine triphosphate

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kilograms daily. From the perspective of biochemistry, ATP is classified as a nucleoside triphosphate, which indicates that it consists of three components: a...

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