Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Chemical compound
Tetrahydroisoquinoline (TIQ or THIQ) is an organic compound with the chemical formula C9H11N. Classified as a secondary amine, it is derived from isoquinoline by hydrogenation. It is a colorless viscous liquid that is miscible with most organic solvents. The tetrahydroisoquinoline skeleton is encountered in a number of bioactive compounds and drugs.[2][3]
^"1,2,3,4-Tetrahydroisoquinoline". pubchem.ncbi.nlm.nih.gov. Retrieved 12 December 2021.
^Mitchenson, Andrew (2000). "Saturated nitrogen heterocycles". Journal of the Chemical Society, Perkin Transactions 1 (17): 2862–2892. doi:10.1039/A908537H.
^Cite error: The named reference Scott was invoked but never defined (see the help page).
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Tetrahydroisoquinoline (TIQ or THIQ) is an organic compound with the chemical formula C9H11N. Classified as a secondary amine, it is derived from isoquinoline...
aldehyde forms an imine, which undergoes a cyclization to form a tetrahydroisoquinoline instead of the dihydroisoquinoline. In enzymology, the (S)-norcoclaurine...
as isoquinazepon, is a drug which is a fused benzodiazepine and tetrahydroisoquinoline derivative. It was developed in the 1960s but was never marketed...
the biosynthetic pathway, only the phenethylamine fragment of the tetrahydroisoquinoline ring system is formed via DOPA; the remaining carbon atoms come...
harveyanum, Ocotea duckei, and others. It belongs to the class of tetrahydroisoquinoline alkaloids. Dimerization of coclaurine leads to the biscoclaurine...
disease. Morphine is biosynthesized in the opium poppy from the tetrahydroisoquinoline reticuline. It is converted into salutaridine, thebaine, and oripavine...
Salsolinol has been used as a starting material to prepare some tetrahydroisoquinoline-based prospective drugs. Salsolinol is found in several edible plants...
Erythravine is a tetrahydroisoquinoline alkaloid found in the plant Erythrina mulungu and other species of the genus Erythrina. Some laboratory research...
Anhalidine is a naturally occurring tetrahydroisoquinoline based alkaloid which can be isolated from Lophophora williamsii; it has also been detected other...
Decahydroisoquinoline can be formed by the hydrogenation of isoquinoline or tetrahydroisoquinoline. There are four stereoisomers of decahydroisoquinoline which differ...
action. Partial saturation of the benzylisoquinoline ring to the tetrahydroisoquinoline ring provided an even further increase in potency of the molecules...
IUPAC name (Z)-1-(3,4-diethoxybenzylidene)-6,7-diethoxy-1,2,3,4-tetrahydroisoquinoline CAS Number 14009-24-6 N PubChem CID 1712095 DrugBank DB06751 Y ChemSpider...
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