Human chromosome 8 pair after G-banding. One is from mother, one is from father.
Chromosome 8 pair in human male karyogram.
Features
Length (bp)
146,259,331 (CHM13)[1]
No. of genes
646 (CCDS)[2]
Type
Autosome
Centromere position
Submetacentric[3] (45.2 Mbp[4])
Complete gene lists
CCDS
Gene list
HGNC
Gene list
UniProt
Gene list
NCBI
Gene list
External map viewers
Ensembl
Chromosome 8
Entrez
Chromosome 8
NCBI
Chromosome 8
UCSC
Chromosome 8
Full DNA sequences
RefSeq
NC_000008 (FASTA)
GenBank
CM000670 (FASTA)
Chromosome 8 is one of the 23 pairs of chromosomes in humans. People normally have two copies of this chromosome. Chromosome 8 spans about 146 million base pairs (the building material of DNA) and represents between 4.5 and 5.0% of the total DNA in cells.[5]
About 8% of its genes are involved in brain development and function, and about 16% are involved in cancer. A unique feature of 8p is a region of about 15 megabases that appears to have a high mutation rate. This region shows a significant divergence between human and chimpanzee, suggesting that its high mutation rates have contributed to the evolution of the human brain.[5]
^"Homo sapiens isolate CHM13 chromosome 8". National Library of Medicine /accessdate=2023-01-13. 4 April 2022.
^Cite error: The named reference CCDS was invoked but never defined (see the help page).
^Tom Strachan; Andrew Read (2 April 2010). Human Molecular Genetics. Garland Science. p. 45. ISBN 978-1-136-84407-2.
^Genome Decoration Page, NCBI. Ideogram data for Homo sapience (850 bphs, Assembly GRCh38.p3). Last update 2014-06-03. Retrieved 2017-04-26.
^ abTabarés-Seisdedos R, Rubenstein JL; Rubenstein (2009). "Chromosome 8p as a potential hub for developmental neuropsychiatric disorders: implications for schizophrenia, autism and cancer". Mol Psychiatry. 14 (6): 563–89. doi:10.1038/mp.2009.2. PMID 19204725. S2CID 11118479.
Chromosome8 is one of the 23 pairs of chromosomes in humans. People normally have two copies of this chromosome. Chromosome8 spans about 146 million...
Trisomy 8 causes Warkany syndrome 2, a human chromosomal disorder caused by having three copies (trisomy) of chromosome8. It can appear with or without...
A chromosome is a package of DNA with part or all of the genetic material of an organism. In most chromosomes, the very long thin DNA fibers are coated...
In genetics, chromosome translocation is a phenomenon that results in unusual rearrangement of chromosomes. This includes balanced and unbalanced translocation...
Chromosome 21 is one of the 23 pairs of chromosomes in humans. Chromosome 21 is both the smallest human autosome and chromosome, with 45 million base...
derivative chromosome (der) is a structurally rearranged chromosome generated either by a chromosome rearrangement involving two or more chromosomes or by...
A chromosomal abnormality, chromosomal anomaly, chromosomal aberration, chromosomal mutation, or chromosomal disorder is a missing, extra, or irregular...
The Y chromosome is one of two sex chromosomes in therian mammals and other organisms. Along with the X chromosome, it is part of the XY sex-determination...
Chromosome 2 is one of the twenty-three pairs of chromosomes in humans. People normally have two copies of this chromosome. Chromosome 2 is the second-largest...
non-sex chromosomes. Chromosome 1 spans about 249 million nucleotide base pairs, which are the basic units of information for DNA. It represents about 8% of...
A ring chromosome is an aberrant chromosome whose ends have fused together to form a ring. Ring chromosomes were first discovered by Lilian Vaughan Morgan...
The Philadelphia chromosome or Philadelphia translocation (Ph) is a specific genetic abnormality in chromosome 22 of leukemia cancer cells (particularly...
The X chromosome is one of the two sex chromosomes in many organisms, including mammals, and is found in both males and females. It is a part of the XY...
The list of organisms by chromosome count describes ploidy or numbers of chromosomes in the cells of various plants, animals, protists, and other living...
A karyotype is the general appearance of the complete set of chromosomes in the cells of a species or in an individual organism, mainly including their...
A pair of homologous chromosomes, or homologs, is a set of one maternal and one paternal chromosome that pair up with each other inside a cell during fertilization...
no longer diagnosed Trisomy 8, known as Warkany syndrome 2, a condition where a person has an extra copy of chromosome8. This disambiguation page lists...
an organism has at least one more chromosome than normal, i.e., there may be three or more copies of the chromosome rather than the expected two copies...
Chromosome 22 is one of the 23 pairs of chromosomes in human cells. Humans normally have two copies of chromosome 22 in each cell. Chromosome 22 is the...
complete sets of chromosomes. A cell with any number of complete chromosome sets is called a euploid cell. An extra or missing chromosome is a common cause...
a chromosome rearrangement in which a segment of a chromosome becomes inverted within its original position. An inversion occurs when a chromosome undergoes...
An autosome is any chromosome that is not a sex chromosome. The members of an autosome pair in a diploid cell have the same morphology, unlike those in...
Global Information
