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Sodium dodecyl sulfate information


Sodium lauryl sulfate
Space-filling model of the sodium dodecyl sulfate crystal
Space-filling model of the dodecyl sulfate ion
Names
Preferred IUPAC name
Sodium dodecyl sulfate
Other names
Sodium monododecyl sulfate; Sodium lauryl sulfate; Sodium monolauryl sulfate; Sodium dodecanesulfate; dodecyl alcohol, hydrogen sulfate, sodium salt; n-dodecyl sulfate sodium; Sulfuric acid monododecyl ester sodium salt
Identifiers
CAS Number
  • 151-21-3 checkY
3D model (JSmol)
  • Interactive image
ChEBI
  • CHEBI:8984 checkY
ChEMBL
  • ChEMBL23393 checkY
ChemSpider
  • 8677 checkY
DrugBank
  • DB00815 checkY
ECHA InfoCard 100.005.263 Edit this at Wikidata
E number E487 (thickeners, ...)
PubChem CID
  • 3423265
UNII
  • 368GB5141J checkY
CompTox Dashboard (EPA)
  • DTXSID1026031 Edit this at Wikidata
InChI
  • InChI=1S/C12H26O4S.Na/c1-2-3-4-5-6-7-8-9-10-11-12-16-17(13,14)15;/h2-12H2,1H3,(H,13,14,15);/q;+1/p-1 checkY
    Key: DBMJMQXJHONAFJ-UHFFFAOYSA-M checkY
SMILES
  • CCCCCCCCCCCCOS(=O)([O-])=O.[Na+]
Properties
Chemical formula
C12H25NaSO4
Molar mass 288.372 g/mol
Appearance white or cream-colored solid
Odor odorless
Density 1.01 g/cm3
Melting point 206 °C (403 °F; 479 K)
Surface tension:
CMC
8.2 mM at 25 °C[1]
Refractive index (nD)
1.461
Pharmacology
ATC code
A06AG11 (WHO)
Hazards
Lethal dose or concentration (LD, LC):
LD50 (median dose)
1288 mg/kg (rat, oral)
Related compounds
Other anions
Sodium laureth sulfate
Sodium myreth sulfate
Other cations
Ammonium lauryl sulfate
Potassium lauryl sulfate
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

Sodium dodecyl sulfate (SDS) or sodium lauryl sulfate (SLS), sometimes written sodium laurilsulfate, is an organic compound with the formula CH3(CH2)11OSO3Na and structure H3C−(CH2)11−O−S(=O)2−ONa+. It is an anionic surfactant used in many cleaning and hygiene products. This compound is the sodium salt of the 12-carbon organosulfate. Its hydrocarbon tail combined with a polar "headgroup" give the compound amphiphilic properties that make it useful as a detergent. SDS is also component of mixtures produced from inexpensive coconut and palm oils. SDS is a common component of many domestic cleaning, personal hygiene and cosmetic, pharmaceutical, and food products, as well as of industrial and commercial cleaning and product formulations.[2]

  1. ^ P. Mukerjee, P. & Mysels, K. J. (1971), "Critical Micelle Concentration of Aqueous Surfactant Systems," NSRDS-NBS 36, Washington, DC: US. Government Printing Office.[full citation needed][page needed]
  2. ^ Cite error: The named reference UllmannSurf was invoked but never defined (see the help page).

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Sodium dodecyl sulfate

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Sodium dodecyl sulfate (SDS) or sodium lauryl sulfate (SLS), sometimes written sodium laurilsulfate, is an organic compound with the formula CH3(CH2)11OSO3Na...

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Sodium laureth sulfate

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federal law. Sodium lauroyl sarcosinate Sodium dodecyl sulfate Sodium myreth sulfate Sodium pareth sulfate Magnesium laureth sulfate Sodium dodecylbenzenesulfonate...

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Lysis buffer

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nondenaturing (will not disrupt protein functions). Ionic detergents like sodium dodecyl sulfate (SDS) and cationic detergents like ethyl trimethyl ammonium bromide...

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Ammonium lauryl sulfate

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Ammonium lauryl sulfate (ALS) is the common name for ammonium dodecyl sulfate (CH3(CH2)10CH2OSO3NH4). The anion consists of a nonpolar hydrocarbon chain...

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Gel electrophoresis

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including urea in the buffer, while proteins are denatured using sodium dodecyl sulfate, usually as part of the SDS-PAGE process. For full denaturation...

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Western blot

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procedure to visualize a certain protein on the blot membrane. Sodium dodecyl sulfate–polyacrylamide gel electrophoresis (SDS-PAGE) is generally used...

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Critical micelle concentration

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critical micelle temperature. For example, the value of CMC for sodium dodecyl sulfate in water (without other additives or salts) at 25 °C, atmospheric...

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Polyacrylamide gel electrophoresis

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similar mass-to-charge ratio). This procedure is called SDS-PAGE. Sodium dodecyl sulfate polyacrylamide gel electrophoresis (SDS-PAGE) is a method of separating...

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Foaming agent

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inexpensive and effective foamer. Sodium lauryl sulfate (also known as sodium dodecyl sulfate or SDS) and ammonium lauryl sulfate (ALS) are commonly used alternatives...

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Benzethonium chloride

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to titrate the quantity of sodium dodecyl sulfate in a mixture of sodium dodecyl sulfate, sodium chloride and sodium sulfate, using dimidium bromide-sulphan...

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Eastern blot

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term "eastern blot(ting)", most use phosphoprotein blotted from sodium dodecyl sulfate–polyacrylamide gel electrophoresis (SDS-PAGE) gel on to a polyvinylidene...

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Page

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PAGE, the acronym of Polyacrylamide gel electrophoresis SDS-PAGE, sodium dodecyl sulfate polyacrylamide gel electrophoresis PAGE XML (Page Analysis and Ground-Truth...

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Amphiphile

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either ionic, or non-ionic. Some typical members of this group are: sodium dodecyl sulfate (anionic), benzalkonium chloride (cationic), cocamidopropyl betaine...

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Lauryl tryptose broth

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Dipotassium phosphate : 2.75, Potassium dihydrogen phosphate : 2.75, Sodium dodecyl sulfate : 0.1 pH 6.8 ± 0.2 Samples positive for gas production are transferred...

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Organosulfate

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amine to neutralize the sulfate group. Examples include: sodium lauryl sulfate (also known as sulfuric acid mono dodecyl ester sodium salt) and related potassium...

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Potassium lauryl sulfate

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Potassium lauryl sulfate (potassium dodecyl sulfate) a detergent similar to sodium lauryl sulfate. Potassium lauryl sulfate is used in mud soaps. It has...

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Bradford protein assay

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An exception of note is elevated concentrations of detergent. Sodium dodecyl sulfate (SDS), a common detergent, may be found in protein extracts because...

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SDS

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Safety data sheet, on chemicals Sodium dodecyl sulfate, a synthetic organic compound SDS-PAGE, sodium dodecyl sulfate polyacrylamide gel electrophoresis...

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Deep eutectic solvent

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and self-assembly of solutes. For example, the self-assembly of sodium dodecyl sulfate (SDS) in DES has recently been studied, implying DES can form microemulsions...

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Emulsifying wax

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or a petroleum-based wax) is treated with a detergent (typically sodium dodecyl sulfate or polysorbates) to cause it to make oil and water bind together...

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Protein purification

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molecular weight via size exclusion chromatography or by SDS-PAGE (sodium dodecyl sulfate-polyacrylamide gel electrophoresis) analysis. Proteins are often...

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Micellar solubilization

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Solubilization of n-Decane and Benzene by Micellar Solutions of Sodium Dodecyl Sulfate". Journal of Colloid and Interface Science 245, 371–382 (2002),...

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Cocamidopropyl betaine

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regular analytical control. CAPB is also used as a co-surfactant with Sodium dodecyl sulfate for promoting the formation of gas hydrates. CAPB, as an additive...

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Dodecanol

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pharmaceuticals. Millions of tons of sodium dodecylsulfate (SDS) are produced annually by sulfation of dodecyl alcohol: SO3 + CH3(CH2)10CH2OH → CH3(CH2)10CH2OSO3H...

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Surfactant

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as sulfate, sulfonate, phosphate, and carboxylates. Prominent alkyl sulfates include ammonium lauryl sulfate, sodium lauryl sulfate (sodium dodecyl sulfate...

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Alkaline lysis

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alkaline solution consisting of the detergent sodium dodecyl sulfate (SDS) and a strong base such as sodium hydroxide (NaOH) is prepared and then added...

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Gel electrophoresis of proteins

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give additional information about a specific protein. SDS-PAGE, sodium dodecyl sulfate polyacrylamide gel electrophoresis, describes a collection of related...

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Mouth ulcer

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aphthous stomatitis, see the epidemiology of aphthous stomatitis. Sodium dodecyl sulfate Vorvick LJ, Zieve D. "Mouth ulcers on MedlinePlus". A.D.A.M., Inc...

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