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Polyclonal antibodies information


Polyclonal antibodies (pAbs) are antibodies that are secreted by different B cell lineages within the body (whereas monoclonal antibodies come from a single cell lineage). They are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.

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Polyclonal antibodies

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Polyclonal antibodies (pAbs) are antibodies that are secreted by different B cell lineages within the body (whereas monoclonal antibodies come from a...

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Polyclonal B cell response

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"mother" cell. The antibodies thus produced in a polyclonal response are known as polyclonal antibodies. The heterogeneous polyclonal antibodies are distinct...

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Immunosuppressive drug

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from horse serum, and Thymoglobuline, obtained from rabbit serum. Polyclonal antibodies affect all lymphocytes and cause general immunosuppression, possibly...

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Monoclonal antibody

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recognized by the antibody). In contrast, polyclonal antibodies bind to multiple epitopes and are usually made by several different antibody-secreting plasma...

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Neutralizing antibody

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infected and recovered patient containing polyclonal antibodies against the infectious agent. This showed that antibodies could be used as an effective treatment...

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Symphogen

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based on recombinant monoclonal antibody mixtures. These drugs are different from the polyclonal antibodies, as each antibody in the mixture is produced from...

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Immunohistochemistry

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The antibodies can be isolated from the animal’s whole serum. Polyclonal antibody production will result in a mixture of different antibodies and will...

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Coombs test

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The direct Coombs test detects antibodies that are stuck to the surface of the red blood cells. Since these antibodies sometimes destroy red blood cells...

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Synthetic antibody

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traditional monoclonal or polyclonal antibodies are used and offer many inherent advantages over animal-derived antibodies, including comparatively low...

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Hybridoma technology

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absence of antibody synthesis. In contrast to polyclonal antibodies, which are mixtures of many different antibody molecules, the monoclonal antibodies produced...

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Antibody

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different IgG (polyclonal IgG). In contrast, monoclonal antibodies are identical antibodies produced by a single B cell. Heterodimeric antibodies, which are...

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Passive antibody therapy

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prevalence of usage. The process of manufacturing polyclonal antibodies is similar to that of monoclonal antibodies, which begins with inoculation of antigen...

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Genzyme

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Medix Biotech, Inc., a producer and supplier of monoclonal and polyclonal antibodies, immunoassay components, and immunodiagnostic services. In the same...

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Human metapneumovirus

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immunofluorescence assays for detection of hMPV-specific antibodies the use of polyclonal antibodies and direct isolation in cultured cells. Though hMPV was...

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Thymoglobulin

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immunoglobulin preparation made of purified polyclonal antibodies derived from rabbits. While these antibodies have a variety of specificities, their main...

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Nicotine vaccine

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Nicotine vaccine uses active immunization as the methodology to create polyclonal antibodies to the antigens, which is then used to treat drug abuse. The immune...

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Imugene

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The antibodies produced following the vaccination are a ‘polyclonal’ mixture of antibodies that bind to different parts of the vaccine antigen. HER-Vaxx...

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Protein detection

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with 46.4% raw defatted walnut and 34.9% roasted defatted walnut. Polyclonal antibodies are generated in 1 sheep, 1 goat, and 3 New Zealand white rabbits...

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Influenza

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pathology. Other forms of therapy in development include monoclonal and polyclonal antibodies that target viral proteins, convalescent plasma, different approaches...

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Rh disease

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re-exposed, and these IgG anti-Rh(D) antibodies do cross the placenta and enter fetal circulation. These antibodies are directed against the Rhesus (Rh)...

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Antivenom

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immunoglobulin, is a specific treatment for envenomation. It is composed of antibodies and used to treat certain venomous bites and stings. Antivenoms are recommended...

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Redback spider

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non-lethal doses. The horse immune systems makes polyclonal antibodies. Blood plasma, containing the antibodies, is extracted by plasmapheresis. The plasma...

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Bestoxin

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confirmed that these neurotoxins react with polyclonal antibodies and it is proposed that polyclonal antibodies will neutralize the N-terminus domain and...

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Humoral immunity

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1897, Paul Ehrlich showed that antibodies form against the plant toxins ricin and abrin, and proposed that these antibodies are responsible for immunity...

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Bordetella pertussis

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the low specificity, it is common to receive false positives with polyclonal antibodies occurring. Several diagnostic tests are available, particularly...

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Cold sensitive antibodies

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Cold sensitive antibodies (CSA) are antibodies sensitive to cold temperature. Some cold sensitive antibodies are pathological and can lead to blood disorder...

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Nomenclature of monoclonal antibodies

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nomenclature of monoclonal antibodies is a naming scheme for assigning generic, or nonproprietary, names to monoclonal antibodies. An antibody is a protein that...

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Plasmacytoma

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(serum), allowing the analysis of antibodies. Normal blood serum contains a range of antibodies and are said to be polyclonal, whereas serum from a person...

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