Species of bacterium causing pertussis or whooping cough
Bordetella pertussis
Scientific classification
Domain:
Bacteria
Phylum:
Pseudomonadota
Class:
Betaproteobacteria
Order:
Burkholderiales
Family:
Alcaligenaceae
Genus:
Bordetella
Species:
B. pertussis
Binomial name
Bordetella pertussis
(Bergey et al. 1923) Moreno-López 1952
Bordetella pertussis is a Gram-negative, aerobic, pathogenic, encapsulated coccobacillus bacterium of the genus Bordetella, and the causative agent of pertussis or whooping cough. Its virulence factors include pertussis toxin, adenylate cyclase toxin, filamentous hæmagglutinin, pertactin, fimbria, and tracheal cytotoxin.
The bacteria are spread by airborne droplets and the disease's incubation period is 7–10 days on average (range 6–20 days).[1][2] Humans are the only known reservoir for B. pertussis.[3] The complete B. pertussis genome of 4,086,186 base pairs was published in 2003.[4] Compared to its closest relative B. bronchiseptica, the genome size is greatly reduced. This is mainly due to the adaptation to one host species (human) and the loss of capability of survival outside a host body.[5]
Like B. bronchiseptica, B. pertussis can express a flagellum-like structure, even though it has been historically categorized as a nonmotile bacterium.[6]
^Heymann DL, ed. (2008). Pertussis; in Control of Communicable Diseases Manual (19th ed.). Washington DC: American Public Health Association. p. 457. ISBN 978-0-87553-189-2.
^Organisation mondiale de la santé, World Health Organization (1998). Relevé épidémiologique hebdomadaire (Online) = Weekly epidemiological record. Organisation mondiale de la sante. OCLC 301147153.
^Havers FP, Moro PL, Hariri S, Skoff T (2015). "Pertussis". In Atkinson W, Wolfe S, Hamborsky J (eds.). Epidemiology and Prevention of Vaccine-Preventable Diseases: The Pink Book (13th ed.). Centers for Disease Control and Prevention, Public Health Foundation.
^Parkhill J, Sebaihia M, Preston A, Murphy LD, Thomson N, Harris DE, et al. (September 2003). "Comparative analysis of the genome sequences of Bordetella pertussis, Bordetella parapertussis and Bordetella bronchiseptica". Nature Genetics. 35 (1): 32–40. doi:10.1038/ng1227. PMID 12910271.
^Locht C (2007). Bordetella: molecular microbiology. Wymondham: Horizon Bioscience. ISBN 978-1-904933-31-1. OCLC 159579443.
^Hoffman CL, Gonyar LA, Zacca F, Sisti F, Fernandez J, Wong T, et al. (May 2019). "Bordetella pertussis Can Be Motile and Express Flagellum-Like Structures". mBio. 10 (3): e00787–19. doi:10.1128/mBio.00787-19. PMC 6520453. PMID 31088927.
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Pertussis toxin (PT) is a protein-based AB5-type exotoxin produced by the bacterium Bordetellapertussis, which causes whooping cough. PT is involved in...
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conjunction with Bordetellapertussis infections (whooping cough), although not always. Weyant, Robbin S.; et al. (1995). "Bordetella holmesii sp. nov...
caused by a bacterial infection such as Mycoplasma pneumoniae or Bordetellapertussis. Risk factors include exposure to tobacco smoke, dust, and other...
of the adenylate cyclase toxin (ACT or CyaA; TC# 1.C.11.1.4) of Bordetellapertussis forms a small cation-selective channel, disrupting the permeability...
whooping cough, Bordetella pertussis. Bordetella bronchiseptica and Bordetella parapertussis, also able to cause pertussis-like symptoms, also produce...
Tracheal cytotoxin (TCT) is a 921 dalton glycopeptide released by Bordetellapertussis, Vibrio fischeri (as a symbiosis chemical), and Neisseria gonorrhoeae...
Acinetobacter strains may grow on solid media as coccobacilli. Bordetellapertussis is a Gram-negative coccobacillus responsible for causing whooping...
Bordet-Gengou and modified Regan-Lowe media for the isolation of Bordetellapertussis and Bordetella parapertussis". J. Clin. Microbiol. 26 (12): 2661–3. doi:10...
Adenylate cyclase toxin (CyaA) is released from bacterium Bordetellapertussis by the T1SS (Type 1 secretion system) and released in the host’s respiratory...
Bordetella hinzii is a Gram-negative, oxidase+ and catalase-positive, short rod-shaped bacterium from the genus Bordetella isolated from a patient who...
occurs with inhalation. Bordetellapertussis targets cilia of the upper respiratory tract which are damaged by the pertussis toxin, an ADP-ribosyltransferase...
toxins secreted by pathogenic bacteria such as Bacillus anthracis, Bordetellapertussis, Pseudomonas aeruginosa, and Vibrio vulnificus during infections...
levels of air pollution or bacteria such as Mycoplasma pneumoniae or Bordetellapertussis. Diagnosis is typically based on a person's signs and symptom. The...
phenotypically identical. Bordetella trematum and B. holmesii are the only species that do not colonize the respiratory tract. B. pertussis and B. parapertussis...
notable bacterium that produces filamentous haemagglutinin adhesin is Bordetellapertussis, which uses this protein as a virulence factor. Adhesin (disambiguation)...
(J15.0), Escherichia coli (J15.5), Pseudomonas aeruginosa (J15.1), Bordetellapertussis, and Moraxella catarrhalis are the most common. These bacteria often...