Of maternal-fetal blood incompatibilities: 16% without antibody therapy, 0.1% with therapy
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Rh disease (also known as rhesus isoimmunization, Rh (D) disease, or rhesus incompatibility, and blue baby disease) is a type of hemolytic disease of the fetus and newborn (HDFN). HDFN due to anti-D antibodies is the proper and currently used name for this disease as the Rh blood group system actually has more than 50 antigens and not only the D-antigen. The term "Rh Disease" is commonly used to refer to HDFN due to anti-D antibodies, and prior to the discovery of anti-Rho(D) immune globulin, it was the most common type of HDFN. The disease ranges from mild to severe, and occurs in the second or subsequent pregnancies of Rh-D negative women when the biologic father is Rh-D positive.
Due to several advances in modern medicine, HDFN due to anti-D is preventable by treating the mother during pregnancy and soon after delivery with an injection of anti-Rho(D) immune globulin (Rhoclone, Rhogam, AntiD). With successful mitigation of this disease by prevention through the use of anti-Rho(D) immune globulin, other antibodies are more commonly the cause of HDFN today.
Rhdisease (also known as rhesus isoimmunization, Rh (D) disease, or rhesus incompatibility, and blue baby disease) is a type of hemolytic disease of the...
Rh(D) and Rh antigens confer significant risk of hemolytic disease of the newborn. The Rh blood group system has two sets of nomenclatures: one developed...
shown the anti-RhD type to be the most common cause of HDFN, followed by anti-RhE, anti-RhC, and anti-Rhc. Signs of hemolytic disease of the newborn include...
occasionally a blood transfusion with D positive RBCs. Rhdisease can develop in these cases. Rh negative blood types are much less common in Asian populations...
Erythroblastosis fetalis, also known as Rhdisease, is the only immune cause of hydrops fetalis. Rhdisease is a hemolytic disease of newborns. Pregnant mothers...
Hemolytic disease of the newborn (also known as HDN or erythroblastosis fetalis) Rh D hemolytic disease of the newborn (also known as Rhdisease) ABO hemolytic...
example, blood) or organ can cause graft-versus-host disease. A type of immune reactivity known as Rhdisease can be observed in pregnant women. These special...
lepidopterist. He was honoured for his pioneering work on prevention of Rhdisease of the newborn, and also for his work on the genetics of the Lepidoptera...
associated with a blood type, named after the monkey Rhdisease, also known as rhesus disease 9142 Rhesus, an asteroid Rhesus Glacier, Antarctica Search...
RHD, the Rhesus factor antigen. It is currently at Phase III trials for Rhdisease. World Health Organization (2010). "International Nonproprietary Names...
the role of rhesus D antibodies in the causation of Rhdisease and the prevention of Rhdisease. He graduated from Columbia University and the New York...
idiopathic or result from an underlying condition. Rhdisease, one of the causes of hemolytic disease of the newborn Transfusion reaction to blood transfusions...
immunologist who developed the Rho(D) immune globulin vaccine against Rhdisease, a leading cause of erythroblastosis fetalis. Pollack co-developed the...
Complete blood count Blood type Rh-negative antenatal patients should receive RhoGAM at 28 weeks to prevent Rhdisease. Indirect Coombs test (AGT) to assess...
treatment prevents sensitization that can lead to Rhdisease, but does not prevent or treat the underlying disease itself. Specific antibodies are produced by...
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