IFNA2 information

IFNA2
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1RH2, 3S9D, 1ITF, 2LAG, 4YPG, 2KZ1, 2HYM, 2LMS, 3SE3, 4Z5R
Identifiers
Aliases	IFNA2, IFN-alphaA, IFNA, IFNA2B, INFA2, interferon, alpha 2, interferon alpha 2, IFN-alpha-2, leIF A
External IDs	OMIM: 147562 MGI: 107666 HomoloGene: 86655 GeneCards: IFNA2
Gene location (Human)
Chr.	Chromosome 9 (human)
End	21,385,398 bp
Gene location (Mouse)
Chr.	Chromosome 4 (mouse)
End	88,602,149 bp
RNA expression pattern
	Top expressed in
	corpus callosum; ; putamen; ; Achilles tendon; ; hippocampus proper; ; caudate nucleus; ; temporal lobe; ; amygdala; ; mesencephalon; ; substantia nigra; ; frontal lobe;
	Top expressed in
	lacrimal gland;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	cytokine activity; type I interferon receptor binding; protein binding; cytokine receptor binding;
Cellular component	extracellular region; extracellular space; collagen-containing extracellular matrix;
Biological process	apoptotic process; defense response; negative regulation of viral entry into host cell; response to exogenous dsRNA; cell-cell signaling; negative regulation of T-helper 2 cell cytokine production; blood coagulation; positive regulation of peptidyl-serine phosphorylation of STAT protein; negative regulation of gene expression; positive regulation of transcription, DNA-templated; natural killer cell activation involved in immune response; cell surface receptor signaling pathway; B cell proliferation; humoral immune response; type I interferon signaling pathway; B cell differentiation; positive regulation of phosphorylation; inflammatory response; negative regulation of transcription, DNA-templated; negative regulation of T cell differentiation; T cell activation involved in immune response; defense response to virus; innate immune response; cytokine-mediated signaling pathway; positive regulation of tyrosine phosphorylation of STAT protein; regulation of signaling receptor activity; adaptive immune response;
	Sources:Amigo / QuickGO
Orthologs
	3440
	15965
	ENSG00000188379
	ENSMUSG00000078354
	P01563
	P01573
	NM_000605
	NM_010503
	NP_000596
	NP_034633
	Wikidata
View/Edit Human	View/Edit Mouse

Interferon alpha-2 is a protein that in humans is encoded by the IFNA2 gene.^[5]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000188379 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000078354 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: IFNA2 interferon, alpha 2".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000188379 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000078354 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: IFNA2 interferon, alpha 2".

IFNA2 information

and 26 Related for: IFNA2 information

IFNA2

Interferon type I

Haematopoiesis

Tumor necrosis factor

Cytokine

Ritlecitinib

Erythropoietin

Adipokine

Etanercept

Janus kinase inhibitor

Inflammatory cytokine

Upadacitinib

Ruxolitinib

TNF inhibitor

Tofacitinib

Oclacitinib

Interferon alfa

Denosumab

Cucurbitacin

Interferon

Macrophage inflammatory protein

Myokine

Lymphokine

Eltrombopag

Interferon gamma

Janus kinase