Eltrombopag, sold under the brand name Promacta among others, is a medication used to treat thrombocytopenia (abnormally low platelet counts) and severe aplastic anemia.[3][4] Eltrombopag is sold under the brand name Revolade outside the US and is marketed by Novartis.[5] It is a thrombopoietin receptor agonist.[3] It is taken by mouth.[3][4]
Eltrombopag was discovered as a result of research collaboration between GlaxoSmithKline and Ligand Pharmaceuticals and is transferred to Novartis Pharmaceuticals.[5][6][7]
^ ab"Revolade Product Information". Therapeutic Goods Administration (TGA). Archived from the original on 23 May 2021. Retrieved 23 May 2021.
^"Revolade 25 mg film-coated tablets - Summary of Product Characteristics (SmPC)". (emc). 17 August 2020. Archived from the original on 23 May 2021. Retrieved 22 May 2021.
^ abcde"Promacta- eltrombopag olamine tablet, film coated Promacta- eltrombopag olamine powder, for suspension". DailyMed. Archived from the original on 23 May 2021. Retrieved 22 May 2021.
^ abc"Revolade EPAR". European Medicines Agency (EMA). 17 September 2018. Archived from the original on 23 May 2021. Retrieved 22 May 2021.
^ ab"Ligand Sells Promacta Assets and Royalty for $827 Million" (Press release). Ligand Pharmaceuticals. 5 March 2019. Archived from the original on 24 June 2021. Retrieved 17 June 2021 – via Business Wire.
^"Revolade". GSK Canada. Archived from the original on 28 June 2021. Retrieved 17 June 2021.
^"Novartis announces completion of transactions with GSK". Sandoz (Press release). Archived from the original on 24 June 2021. Retrieved 17 June 2021.
Eltrombopag, sold under the brand name Promacta among others, is a medication used to treat thrombocytopenia (abnormally low platelet counts) and severe...
thrombopoietin and then developed thrombocytopenia. Romiplostim and Eltrombopag, structurally different compounds that stimulate the same pathway, are...
(FDA) for long-term treatment of adult chronic ITP on August 22, 2008. Eltrombopag (trade name Promacta in the US, Revolade in the EU) is an orally-administered...
mimetics Abciximab Eptifibatide Tirofiban Others: oprelvekin, romiplostim, eltrombopag, argatroban Platelet transfusion is most frequently used to correct unusually...
such as: Ciclosporin Gemfibrozil Certain antiretrovirals Rifampicin Eltrombopag Also, concurrent use of other drugs that cause constipation is not preferred...
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