Interferon alfa (INN) or HuIFN-alpha-Le, trade name Multiferon, is a pharmaceutical drug composed of natural interferon alpha (IFN-α), obtained from the leukocyte fraction of human blood following induction with Sendai virus. Interferon alfa contains several naturally occurring IFN-α subtypes and is purified by affinity chromatography. Although the pharmaceutical product is often simply called "interferon alpha" or "IFN-α" like its endogenous counterpart, the product's International nonproprietary name (INN) is interferon alfa (the spelling of 'alfa' with 'f' reflects INN naming conventions).
Interferon alfa is used in a variety of treatments, including certain forms of leukemia, malignant melanoma, non-Hodgkin's lymphoma,[3] hepatitis B, and hepatitis C.[4][5][6] It is typically administered as an injection under the skin.[1]
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^Williams CD, Linch DC (1997). "Interferon alfa-2a". British Journal of Hospital Medicine. 57 (9): 436–9. PMID 9274677.
^Woo MH, Burnakis TG (March 1997). "Interferon alfa in the treatment of chronic viral hepatitis B and C". The Annals of Pharmacotherapy. 31 (3): 330–7. doi:10.1177/106002809703100312. PMID 9066942. S2CID 31113832.
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Interferonalfa (INN) or HuIFN-alpha-Le, trade name Multiferon, is a pharmaceutical drug composed of natural interferon alpha (IFN-α), obtained from the...
is interferonalfa. The recombinant type is interferon alfacon-1. The pegylated types are pegylated interferonalfa-2a and pegylated interferonalfa-2b...
Interferons (IFNs, /ˌɪntərˈfɪərɒn/ IN-tər-FEER-on) are a group of signaling proteins made and released by host cells in response to the presence of several...
Interferon gamma (IFNG or IFN-γ) is a dimerized soluble cytokine that is the only member of the type II class of interferons. The existence of this interferon...
fungal infections in cancer patients Interferonalfa, used to treat hepatitis C and multiple sclerosis Interferon beta, used to treat multiple sclerosis...
Epoetin alfa is a human erythropoietin produced in cell culture using recombinant DNA technology. Authorised by the European Medicines Agency on 28 August...
called erythropoiesis-stimulating agents (ESA): two examples are epoetin alfa and epoetin beta. ESAs are used in the treatment of anemia in chronic kidney...
responses to some cytokines, such as interferon-gamma. JAK1 and JAK2 are involved in type II interferon (interferon-gamma) signalling, whereas JAK1 and...
hepatitis C (in which low platelet counts may be a contraindication for interferon treatment). After six weeks of therapy in a phase III trial, eltrombopag...
(SERPINA12) progranulin CTRP-4 Interleukin 8 (IL-8), interleukin 10 (IL-10), interferon gamma (IFN-γ) and inducible protein 10 (IP-10 or CXCL10) have been shown...
antidepressant bupropion lowers production of tumor necrosis factor-alpha and interferon-gamma in mice". International Immunopharmacology. 6 (6): 903–907. doi:10...
respond to a select group of cytokines including interferon type I, interferon type II, interferon type III. and members of the interleukin-10 family...
MD, Bukowski RM, Rixe O, et al. (January 2007). "Sunitinib versus interferonalfa in metastatic renal-cell carcinoma". The New England Journal of Medicine...
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