Human placental lactogen (hPL), also called human chorionic somatomammotropin (hCS) or human chorionic somatotropin, is a polypeptide placental hormone, the human form of placental lactogen (chorionic somatomammotropin). Its structure and function are similar to those of human growth hormone. It modifies the metabolic state of the mother during pregnancy to facilitate energy supply to the fetus. hPL has anti-insulin properties. hPL is a hormone secreted by the syncytiotrophoblast during pregnancy. Like human growth hormone, hPL is encoded by genes on chromosome 17q22-24. It was identified in 1963.[2]
^PDB: 1Z7C; Walsh ST, Kossiakoff AA (May 2006). "Crystal structure and site 1 binding energetics of human placental lactogen". J. Mol. Biol. 358 (3): 773–84. doi:10.1016/j.jmb.2006.02.038. PMID 16546209.
^Josimovich JB, Atwood BL, Goss DA (October 1963). "Luteotrophic, Immunologic and Electrophoretic Properties of Human Placental Lactogen". Endocrinology. 73 (4): 410–20. doi:10.1210/endo-73-4-410. PMID 14068826.
and 28 Related for: Human placental lactogen information
Humanplacentallactogen (hPL), also called human chorionic somatomammotropin (hCS) or human chorionic somatotropin, is a polypeptide placental hormone...
be. Humanplacentallactogen (hPL) is a hormone used in pregnancy to develop fetal metabolism and general growth and development. Humanplacental lactogen...
Placentallactogen, also called chorionic somatomammotropin, is a polypeptide placental hormone, part of the somatotropin family. Its structure and function...
trophoblast. The tumor may secrete humanplacentallactogen, and result in a false-positive pregnancy test. A placental site trophoblastic tumor is a monophasic...
no traces of the human chorionic gonadotropin hormone. Equine chorionic gonadotropin Gonadotropin preparations Humanplacentallactogen Triple test - a...
human testis in vitro". The Journal of Clinical Endocrinology and Metabolism. 85 (5): 2057–67. doi:10.1210/jcem.85.5.6600. PMID 10843196. Placental Hormones...
chromosome 17 and are closely related to human chorionic somatomammotropin (also known as placentallactogen) genes. GH, human chorionic somatomammotropin, and...
Pregnant women have high levels of hormones including glucagon and humanplacentallactogen that increase circulating free fatty acids which increases ketone...
Handwerger S, Freemark M (2000). "The roles of placental growth hormone and placentallactogen in the regulation of human fetal growth and development". J. Pediatr...
PRLR can also bind to and be activated by growth hormone (GH) and humanplacentallactogen (hPL). The PRLR is expressed in the mammary glands, pituitary gland...
secretes progesterone and leptin in addition to human chorionic gonadotropin (hCG) and humanplacentallactogen (HPL); hCG prevents degeneration of the corpus...
gastroparesis (delayed gastric emptying). It raises the level of prolactin in the human body and is used off label to induce and promote breast milk production...
such as in children or elderly adults with growth hormone deficiency, and human studies have shown it to increase both muscle mass and bone mineral density...
growth and cell reproduction. In the past, growth hormone was extracted from human pituitary glands. Growth hormone is now produced by recombinant DNA technology...
"Flavonoid, Silibinin, Inhibits Proliferation and Promotes Cell-Cycle Arrest of Human Colon Cancer". Journal of Surgical Research. 143 (1): 58–65. doi:10.1016/j...
lactation inducer or milk booster, is a substance that promotes lactation in humans and other animals. It may be synthetic, plant-derived, or endogenous. They...
The structure of prolactin is similar to that of growth hormone and placentallactogen. The molecule is folded due to the activity of three disulfide bonds...
epithelium and regulating milk production through osmotic balance. Humanplacentallactogen (HPL) – from the second month of pregnancy, the placenta releases...
lithium. On 16 December 2021, the Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency (EMA) formally recommended market...
adenosine for use in wound-healing deficiencies and diabetes mellitus in humans is currently under clinical investigation. Methotrexate's anti-inflammatory...
induce insulin resistance including cortisol, growth hormone, and humanplacentallactogen. Cortisol counteracts insulin and can lead to increased hepatic...
somatostatin receptors, allow somatostatin to possess a large range of functions. Humans have only one somatostatin gene, SST. Synonyms of "somatostatin" include:[citation...
dose-dependently increases plasma levels of growth hormone (GH) in animals and humans. In addition, similarly to pralmorelin (GHRP-2) and GHRP-6, it slightly...
significantly increases plasma growth hormone (GH) levels in both animals and humans. In addition, ipamorelin stimulates body weight gain in animals. Like pralmorelin...