A promyelocyte (or progranulocyte) is a granulocyte precursor, developing from the myeloblast and developing into the myelocyte. Promyelocytes measure 12–20 microns in diameter. The nucleus of a promyelocyte is approximately the same size as a myeloblast but their cytoplasm is much more abundant.[1] They also have less prominent nucleoli than myeloblasts and their chromatin is more coarse and clumped.[1] The cytoplasm is basophilic and contains primary red/purple granules.[2]
A promyelocyte (or progranulocyte) is a granulocyte precursor, developing from the myeloblast and developing into the myelocyte. Promyelocytes measure...
distinctly basophilic and relatively more abundant than in myeloblasts or promyelocytes, even though myelocytes are smaller cells. Numerous cytoplasmic granules...
granules, which is a major difference from the myeloblast's successor, the promyelocyte. The nucleolus is the site of assembly of ribosomal proteins, which are...
there is an abnormal accumulation of immature granulocytes called promyelocytes. The disease is characterized by a chromosomal translocation involving...
from a common myeloblast (myeloid progenitor) to a common promyelocyte. This promyelocyte gives rise to a unique myelocyte that for the first time can...
Basophilic, Neutrophilic and Eosinophilic, respectively – as in Basophilic promyelocyte. For lymphocytes, the T and B are actual designations. The polychromatic...
types of cells) blood marrow with underdeveloped promyelocytes. These underdeveloped promyelocytes, if fully matured, would have been the missing granulocytes...
reaction. The peripheral blood smear may show myelocytes, metamyelocytes, promyelocytes, and rarely myeloblasts; however, there is a mixture of early mature...
precursors, which are islands of immature precursors cells (myeloblasts and promyelocytes) localized to the center of the intertrabecular space rather than adjacent...
hypergranular form of acute promyelocytic leukemia (FAB - M3). These promyelocytes (not blast cells) have numerous Auer rods in the cytoplasm which gives...
but during an infection neutrophil precursors called myelocytes and promyelocytes are released. Neutrophils have three strategies for directly attacking...
CMML. Monocytosis and the presence of myelocytes, metamyelocytes and promyelocytes is typical of CMML. Specialty Haematology, oncology Causes Environmental...
classification consisting of precursors of neutrophils; specifically, promyelocytes, myelocytes and metamyelocytes. Other cell types are reported if they...
basophils). This classification consists of metamyelocytes, myelocytes and promyelocytes, which may be enumerated separately in the manual differential or reported...
the cell and very little cytoplasm. The next developmental stage, a promyelocyte, still has a large oval nucleus, but there is more cytoplasm in the cell...
proliferating; in people there is evidence that it forces the primary cancerous promyelocytes to differentiate and mature into neutrophils, allowing normal cells...
composition to the primary granules found in immature granulocytic cells like promyelocytes. Although normal, mature neutrophils do contain some primary granules...
infection neutrophil precursors called metamyelocytes, myelocytes and promyelocytes are released. The intra-cellular granules of the human neutrophil have...
support the notion that RAS depends on the presence of the malignant promyelocytes. This has led to the growing deprecation of the term 'retinoic acid...
promyelocytic leukemia (APL) is a specific type of AML. In this leukemia promyelocytes are produced and build up in the bone marrow. A specific chromosome...
hematopoiesis. Maturation arrest of granulopoiesis at the level of promyelocytes. Neutropenia. Osteopenia, may lead to osteoporosis. Prone to recurrent...
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