Agranulocytosis, also known as agranulosis or granulopenia, is an acute condition involving a severe and dangerous lowered white blood cell count (leukopenia, most commonly of neutrophils) and thus causing neutropenia in the circulating blood.[1] It is a severe lack of one major class of infection-fighting white blood cells. People with this condition are at very high risk of serious infections due to their suppressed immune system.
In agranulocytosis, the concentration of granulocytes (a major class of white blood cells that includes neutrophils, basophils, and eosinophils) drops below 200 cells/mm3 of blood.
monocytes). Despite this, "agranulocytosis" remains the most widely used term for the condition.[citation needed] The terms agranulocytosis, granulocytopenia and...
cases and Clozapine Induced Agranulocytosis (CIA) in 0.4%. These are potentially serious side effects and agranulocytosis can result in death. To mitigate...
Agranulocytosis can be presented as whitish or greyish necrotic ulcer in the oral cavity, without any sign of inflammation. Acquired agranulocytosis is...
prone to suffer from metamizole induced agranulocytosis than others. As an example, metamizole-related agranulocytosis seems to be an adverse effect more frequent...
toxic than barbiturates. Today, this substance is no longer used. Agranulocytosis was sometimes reported as adverse effect. Pyrithyldione is also a CYP2D6...
serious risk of severe and sometimes fatal side-effects, including agranulocytosis.[citation needed] While its production and use have been banned in...
antipyretic properties. Its use as a drug is discouraged due to the risk of agranulocytosis. It is used as a reagent for biochemical reactions producing peroxides...
blood cell count, low platelet count, and hair loss, with a risk of agranulocytosis in rare cases. Carbamazepine and phenytoin lower serum levels of mebendazole...
possible side effect is agranulocytosis, a decrease of white blood cells in the blood. Symptoms and signs of agranulocytosis include infectious lesions...
this group although it has the potentially serious side effect of agranulocytosis (lowered white blood cell count) in less than 4% of people. About 30...
cholestatic jaundice Bone marrow suppression, potentially resulting in agranulocytosis, thrombocytopenia, and leukopenia Depression of the thermoregulatory...
Centers for Disease Control and Prevention (CDC) (December 2009). "Agranulocytosis associated with cocaine use – four States, March 2008 – November 2009"...
of the drug. One of the more serious side effects of levamisole is agranulocytosis, or the depletion of the white blood cells. In particular, neutrophils...
numbers of granulocytes (called as granulocytopenia or, if absent, agranulocytosis) such as of neutrophil granulocytes (termed neutropenia). Granulocyte...
increase with dose increases. Likewise rarely it has been associated with agranulocytosis, erythema multiforme and toxic epidermal necrolysis. Severe injection...
including pancytopenia, leukopenia, lymphopenia, thrombocytopenia, agranulocytosis, and neutropenia, autoimmune reactions such as lupus erythematosus...
platelets: rarely, there are major effects of aplastic anemia and agranulocytosis reported and more commonly, there are minor changes such as decreased...
dyscrasias (abnormalities in the cell composition of blood), such as: Agranulocytosis – a drop in white blood cell counts that leaves one open to potentially...
Agranulocytosis, a potentially fatal drop in white blood cell count. Leukopenia, a drop in white blood cell count, not as severe as agranulocytosis....
neutrophil count is the most important indicator of infection risk. Agranulocytosis is an acute form of neutropenia.[citation needed] Low white cell count...
adverse effects include:[citation needed] Allergy to pyrazolones Nausea Agranulocytosis Hepatotoxicity Phenazone is often used in testing the effects of other...
the hapten or immune response. This immune response, also known as agranulocytosis, can explain the adverse drug events which may be seen in captopril...
Global Information