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Myeloblast information


Myeloblast
Myeloblast
Identifiers
THH2.00.04.3.04002
FMA83524
Anatomical terms of microanatomy
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The myeloblast is a unipotent stem cell which differentiates into the effectors of the granulocyte series. It is found in the bone marrow. Stimulation of myeloblasts by G-CSF and other cytokines triggers maturation, differentiation, proliferation and cell survival.[1]

  1. ^ Metcalf D (January 2008). "Hematopoietic cytokines". Blood. 111 (2): 485–91. doi:10.1182/blood-2007-03-079681. PMC 2200848. PMID 18182579.

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Myeloblast

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The myeloblast is a unipotent stem cell which differentiates into the effectors of the granulocyte series. It is found in the bone marrow. Stimulation...

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Promyelocyte

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promyelocyte (or progranulocyte) is a granulocyte precursor, developing from the myeloblast and developing into the myelocyte. Promyelocytes measure 12–20 microns...

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Myeloid leukemia

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malignancy of plasmacytoid dendritic cells. Hematological malignancies Myeloblast transient myeloproliferative disease This article includes a list of related...

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Myeloid tissue

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narrower sense also often used, specifically from the lineage of the myeloblast (the myelocytes, monocytes, and their daughter types). Thus, although...

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Acute myeloid leukemia

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The malignant cell in AML is the myeloblast. In normal development of blood cells (hematopoiesis), the myeloblast is an immature precursor of myeloid...

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Neutrophil

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cell, L-blast=lymphoblast, lymphocyte, Mo-blast=monoblast, monocyte, myeloblast, Pro-M=promyelocyte, myelocyte, Meta-M=metamyelocyte, neutrophil, eosinophil...

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Acute myelomonocytic leukemia

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CFU-GM myeloblasts and monoblasts. AMML occurs with a rapid increase amount in white blood cell count and is defined by more than 20% of myeloblast in the...

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Auer rod

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Myeloblast with an Auer rod (to the left of the nucleus)....

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Myelodysplastic syndrome

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the ability to differentiate. If the overall percentage of bone-marrow myeloblasts rises over a particular cutoff (20% for WHO and 30% for FAB), then transformation...

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Proerythroblast

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difficult to distinguish it from the other "-blast" cells (lymphoblast, myeloblast, monoblast, and megakaryoblast). The cytoplasm is blue in an H&E stain...

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White blood cell

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cell, L-blast=Lymphoblast, Lymphocyte, Mo-blast=Monoblast, Monocyte, Myeloblast, Pro-M=Promyelocyte, Myelocyte, Meta-M=Metamyelocyte, Neutrophil, Eosinophil...

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Myelopoiesis

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and megakaryocytes (leading to platelets) as well as mast cells and myeloblasts, the latter leading to the myelocytic line (granulocytes) and to monocytes...

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Precursor cell

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using blood and muscle precursor cells. Oligodendrocyte precursor cell Myeloblast Thymocyte Meiocyte Megakaryoblast Promegakaryocyte Melanoblast Lymphoblast...

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Bone marrow

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Group Cell type Average fraction Reference range Myelopoietic cells Myeloblasts 0.9 0.2–1.5 Promyelocytes 3.3% 2.1–4.1 Neutrophilic myelocytes 12.7%...

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Eosinophilia

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BCR-JAK2 fusion genes. For this diagnosis, immature eosinophil (e.g. myeloblast) cell counts in the bone marrow and peripheral blood must be less than...

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Myeloid sarcoma

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tumor) is a solid tumor composed of immature white blood cells called myeloblasts. A chloroma is an extramedullary manifestation of acute myeloid leukemia;...

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Leukemoid reaction

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leukemia). It often describes the presence of immature cells such as myeloblasts or red blood cells with nuclei in the peripheral blood. It may be lymphoid...

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Granulopoiesis

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population of monocytes. The first unipotent cell in granulopoiesis is a myeloblast. Committed granulopoiesis consists of maturation stages of unipotent cells...

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Acute erythroid leukemia

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(non- erythroid) are myeloblasts. In rare cases the erythroid lineage is the only obvious component of an acute leukemia; a myeloblast component is not apparent...

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List of distinct cell types in the adult human body

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nervous system Neutrophil granulocyte myeloblast, promyelocyte, myelocyte, metamyelocyte Eosinophil granulocyte myeloblast, promyelocyte, myelocyte, metamyelocyte...

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Cell culture

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Trichoplusia ni Ovary Cellosaurus HL-60 Human Leukemia-60 Human Blood Myeloblast ECACC Cellosaurus HT-1080 Human Fibrosarcoma ECACC Cellosaurus HT-29 Human...

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Bone marrow examination

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5–64.5 49.5 49.7 Female 24.5–72.5 34.1–67.4 50 50.5 Neutrophils (total) Myeloblast 0–8.5 0–5.0 1.5 1.6 Promyelocyte 0–8.5 0–5.5 1 1.3 Myelocyte 1.0–31.7...

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Myelocyte

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cytoplasm is distinctly basophilic and relatively more abundant than in myeloblasts or promyelocytes, even though myelocytes are smaller cells. Numerous...

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Chronic myelomonocytic leukemia

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diagnosed if myeloblasts, monoblasts and promonocytes are <5% of peripheral blood and <10% of bone marrow. CMML-2 is diagnosed if: Myeloblasts, monoblasts...

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Granulocyte

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intermediate cell types exist in this differentiation process, including myeloblasts and promyelocytes.[citation needed] Examples of toxic materials produced...

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Haematopoiesis

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monocytopoiesis thrombocytopoiesis [root]blast Lymphoblast Proerythroblast Myeloblast Monoblast Megakaryoblast pro[root]cyte Prolymphocyte Polychromatophilic...

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Erythropoiesis

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on to produce erythrocytes, as well as mast cells, megakaryocytes and myeloblasts. The process by which common myeloid progenitor cells become fully mature...

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Sideroblastic anemia

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(IWGM-MDS) consensus proposals for the definition and enumeration of myeloblasts and ring sideroblasts". Haematologica. 93 (11): 1712–7. doi:10.3324/haematol...

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