Main staining types when using hematoxylin and eosin (H&E).A basophil granulocyte is surrounded by lightly staining eosinophilic erythrocytes in an H&E staining.
Eosinophilic (Greek suffix -phil-, meaning loves eosin) is the staining of tissues, cells, or organelles after they have been washed with eosin, a dye.
Eosin is an acidic dye for staining cell cytoplasm, collagen, and muscle fibers.[1][2]Eosinophilic describes the appearance of cells and structures seen in histological sections that take up the staining dye eosin.[2] Such eosinophilic structures are, in general, composed of protein.[3]
Eosin is usually combined with a stain called hematoxylin to produce a hematoxylin- and eosin-stained section (also called an H&E stain, HE or H+E section). It is the most widely used histological stain for a medical diagnosis.[3] When a pathologist examines a biopsy of a suspected cancer, they will stain the biopsy with H&E.
Some structures seen inside cells are described as being eosinophilic; for example, Lewy and Mallory bodies.[4]
Some cells are also described as eosinophilic, such as Leukocytes.[5]
^Tubbs, R. Shane; Rizk, Elias; Shoja, Mohammadali; Loukas, Marios; Barbaro, Nicholas; Spinner, Robert J. (2015). Nerves and Nerve Injuries: Vol 1: History, Embryology, Anatomy, Imaging, and Diagnostics. Academic Press. p. 84. ISBN 978-0-12-410447-1.
^ abSharma, Sonal; Khanna, Geetika (2019). Textbook of Pathology and Genetics for Nurses E-Book. Elsevier Health Sciences. p. 9. ISBN 978-8-13-125538-4.
^ abLeong, Franz Joel; Dartois, Veronique; Dick, Thomas (2016). A Color Atlas of Comparative Pathology of Pulmonary Tuberculosis. CRC Press. p. 199. ISBN 978-1-43-983530-2.
^Eosinophilic. Medline Plus. Accessed March 2nd, 2012.
^Dixon, Frank J. (1986). Advances in Immunology, Volume 39. Academic Press. p. 323. ISBN 9780120224395.
Eosinophilic (Greek suffix -phil-, meaning loves eosin) is the staining of tissues, cells, or organelles after they have been washed with eosin, a dye...
Eosinophilic esophagitis (EoE) is an allergic inflammatory condition of the esophagus that involves eosinophils, a type of white blood cell. In healthy...
causes angiostrongyliasis, an infection that is the most common cause of eosinophilic meningitis in Southeast Asia and the Pacific Basin. The nematode commonly...
Eosinophilic pneumonia is a disease in which an eosinophil, a type of white blood cell, accumulates in the lungs. These cells cause disruption of the normal...
Eosinophilic cellulitis, also known as Wells' syndrome (not to be confused with Weil's disease), is a skin disease that presents with painful, red, raised...
Eosinophilic gastroenteritis (EG or EGE), also known as eosinophilic enteritis, is a rare and heterogeneous condition characterized by patchy or diffuse...
Types of eosinophilic leukemia include: Chronic eosinophilic leukemia Acute eosinophilic leukemia Clonal eosinophilia This article includes a list of...
Eosinophilic cystitis is a rare type of interstitial cystitis first reported in 1960 by Edwin Brown. Eosinophilic cystitis has been linked to a number...
Eosinophilic myocarditis is inflammation in the heart muscle that is caused by the infiltration and destructive activity of a type of white blood cell...
Eosinophilic granulomatosis with polyangiitis (EGPA), formerly known as allergic granulomatosis, is an extremely rare autoimmune condition that causes...
Eosinophilic folliculitis is an itchy rash with an unknown cause that is most common among individuals with HIV, though it can occur in HIV-negative individuals...
Eosinophilic fasciitis (/ˌiːəˌsɪnəˈfɪlɪk ˌfæʃiˈaɪtɪs, ˌiːoʊ-, -ˌfæsi-/), also known as Shulman's syndrome, is an inflammatory disease that affects the...
Human eosinophilic granuloma is characterized by abnormal proliferation of Langerhans cells (LCs). LCs are antigen-presenting cells derived from dendritic...
they are terminally differentiated and do not multiply. These cells are eosinophilic or "acid-loving" due to their large acidophilic cytoplasmic granules...
which result in chronic sinusitis. It is also used for the treatment of eosinophilic esophagitis and prurigo nodularis. The most common side effects reported...
genetically predisposed individuals. Eosinophilic gastroenteritis, also known as eosinophilic enteropathy or eosinophilic enteritis – a rare and heterogeneous...
Eosinophilic bronchitis (EB) is a type of airway inflammation due to excessive mast cell recruitment and activation in the superficial airways as opposed...
are present in the more mature forms of myelocytes. Neutrophilic and eosinophilic granules are peroxidase-positive, while basophilic granules are not....
A metamyelocyte is a cell undergoing granulopoiesis, derived from a myelocyte, and leading to a band cell. It is characterized by the appearance of a bent...
Candida species. A parasitic worm is often assumed to be the cause of eosinophilic meningitis when there is a predominance of eosinophils (a type of white...
humanized monoclonal antibody used for the treatment of severe eosinophilic asthma, eosinophilic granulomatosis, and hypereosinophilic syndrome (HES). It recognizes...
Acute eosinophilic leukemia (AEL) is a rare subtype of acute myeloid leukemia with 50 to 80 percent of eosinophilic cells in the blood and marrow. It...
blood film Hematopoiesis "band cell" at Dorland's Medical Dictionary "Eosinophilic band". Archived from the original on 2008-08-29. Retrieved 2009-03-01...
Acute eosinophilic pneumonia (AEP) is an uncommon, acute-onset form of eosinophilic lung disease which varies in severity. Though poorly understood, the...
difficult to treat and are associated with a poor prognosis. Feline eosinophilic keratitis — affecting cats and horses; possibly initiated by feline herpesvirus...
virus-negative lymphoid malignancy, or another predisposing condition such as eosinophilic cellulitis or chronic lymphocytic leukemia. The term papular urticaria...
Eosinophilic vasculitis is a cutaneous condition characterized by an inflammation of blood vessels and the presence of eosinophils. Itchy red bump disease...
recently added GINA-recommended treatment option for both eosinophilic and non-eosinophilic severe, refractory asthma based on azithromycin's efficacy...
Global Information
