Dense granules (also known as dense bodies or delta granules) are specialized secretory organelles. Dense granules are found only in platelets and are smaller than alpha granules.[1] The origin of these dense granules is still unknown, however, it is thought that may come from the mechanism involving the endocytotic pathway.[2] Dense granules are a sub group of lysosome-related organelles (LRO). There are about three to eight of these in a normal human platelet.[3]
^Michelson, A. D. (2013). Platelets (Vol. 3rd ed). Amsterdam: Academic Press.
^Ambrosio, A. L., Boyle, J. A., & Di Pietro, S. M. (2012). Mechanism of platelet dense granule biogenesis: study of cargo transport and function of Rab32 and Rab38 in a model system. Blood, 120(19), 4072–4081. doi:10.1182/blood-2012-04-420745
^McNicol, A., & Israels, S. J. (1999). Platelet dense granules: Structure, function and implications for haemostasis doi:10.1016/S0049-3848(99)00015-8
Densegranules (also known as dense bodies or delta granules) are specialized secretory organelles. Densegranules are found only in platelets and are...
granules, densegranules, and lysosomes. Of these, alpha granules are the most common, making up 50% to 80% of the secretory granules. Alpha granules...
Dense body may refer to: Densegranule, a secretory organelle Ribbon synapse, a type of neuronal synapse Electron-dense portions of smooth muscle This...
Cerebellar granule cells form the thick granular layer of the cerebellar cortex and are among the smallest neurons in the brain. (The term granule cell is...
into dense globules could keep them from reacting with harmful chemicals and safeguard the information coded in their RNA sequence. Stress granules might...
of the densegranules and alpha granules. From the densegranules, serotonin and adenosine diphosphate are released. From the alpha granules come molecules...
fibronectin, platelet-derived growth factor, and chemotactic agents. Delta granules, or dense bodies, contain ADP, calcium, and serotonin, which are platelet-activating...
cytometric assay using mepacrine for study of uptake and release of platelet densegranule contents". Br. J. Haematol. 89 (2): 380–385. doi:10.1111/j.1365-2141...
powders have formed a more densely held mass, then the granulation is milled. This process results in the formation of granules. The process can be very...
Jain N, Gerrard JM (April 1993). "The protein CD63 is in platelet densegranules, is deficient in a patient with Hermansky-Pudlak syndrome, and appears...
condition may involve the alpha granules or the densegranules. Therefore, the following examples include: Platelet alpha-granules Gray platelet syndrome Quebec...
trypanosomes, a group of flagellated protozoans, the kinetoplast exists as a densegranule of DNA within the mitochondrion. Trypanosoma brucei, the parasite which...
In cellular neuroscience, Nissl bodies (also called Nissl granules, Nissl substance or tigroid substance) are discrete granular structures in neurons that...
complex and are known as the densegranules. These typically have a mean diameter around 0.7 μm. Secretion of the dense-granule content takes place after...
into three layers. At the bottom lies the thick granular layer, densely packed with granule cells, along with interneurons, mainly Golgi cells but also including...
McNicol A (April 1996). "The lysosomal granule membrane protein, LAMP-2, is also present in platelet densegranule membranes". Thrombosis and Haemostasis...
provide a unique identity for each homologous pairs. They appear as densegranules during leptotene stage There are more than 2000 chromomeres on 20 chromosomes...
through its interactions with Rab27a appears to be important for the densegranule release from platelets. The mutated Rab27a interaction with Munc13-4...
vacuole membrane, in which the parasite can survive and reproduce. Densegranule Rhoptry Rigoulet, Jacques; Hennache, Alain; Lagourette, Pierre; George...
is a dense structure in the cytoplasm of male germ cells. It is composed mainly of RNA and RNA-binding proteins and is thus a type of RNP granule. Chromatoid...
extracellular matrix extracellular exosome extracellular region platelet densegranule lumen extracellular space Biological process regulation of T cell migration...
mucus produced by the upper airways. The heterogeneous nature of the densegranules within the club cell's cytoplasm suggests that they may not all have...
secretory organelles present in all Apicomplexa along with micronemes and densegranules. Rhoptries and micronemes are localized at the apical complex of the...
retinoic acid phospholipid homeostasis steroid metabolic process platelet densegranule organization regulation of Cdc42 protein signal transduction response...
cells. Spread throughout the parasite are secretory vesicles called densegranules that contain parasite proteins involved in modifying the membrane that...
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