Aggregation of platelets formed during early stage of coagulation
The platelet plug, also known as the hemostatic plug or platelet thrombus, is an aggregation of platelets formed during early stages of hemostasis in response to one or more injuries to blood vessel walls. After platelets are recruited and begin to accumulate around the breakage, their “sticky” nature allows them to adhere to each other. This forms a platelet plug, which prevents more blood from leaving the body as well as any outside contaminants from getting in. The plug provides a temporary blockage of the break in the vasculature. As such, platelet plug formation occurs after vasoconstriction of the blood vessels but before the creation of the fibrin mesh clot, which is the more permanent solution to the injury. The result of the platelet plug formation is the coagulation of blood. It can also be referred to as primary hemostasis.
The plateletplug, also known as the hemostatic plug or platelet thrombus, is an aggregation of platelets formed during early stages of hemostasis in...
each other through receptor bridges: aggregation. Formation of this plateletplug (primary hemostasis) is associated with activation of the coagulation...
vasoconstriction temporary blockage of a hole in a damaged blood vessel by a plateletplug blood coagulation (formation of fibrin clots) Coagulation, the changing...
fibrin, together with platelets, forms a hemostatic plug or clot over a wound site. When the lining of a blood vessel is broken, platelets are attracted, forming...
GPIb-V-IX complex on platelets. The GPIb-V-IX complex binds von Willebrand factor, allowing platelet adhesion and plateletplug formation at sites of...
injury and plug the gap. Simultaneous activation of the coagulation cascade results in the formation of fibrin, which reinforces the plateletplug to create...
matrix that is exposed under the endothelium, form a plateletplug, and then form a thrombus. Platelets are essential in the formation of an occlusive thrombus...
blood flow by causing the aggregation and adhesion of platelets in the blood to form a plateletplug, ceasing blood flow from an open wound. It is hoped...
forces or chemical bonding The accumulation of platelets to the site of a wound to form a plateletplug or a thrombus Flocculation, a process where a solute...
Also called platelets, they take part in blood clotting (coagulation). Fibrin from the coagulation cascade creates a mesh over the plateletplug. About 55%...
time it takes for the bleeding to stop (i.e. the time it takes for a plateletplug to form) is measured. Cessation of bleeding can be determined by blotting...
formation of the plateletplug involved in primary hemostasis (a part of blood clot formation). It does this by inhibiting platelet activation. It is...
aggregation and the formation of primary plateletplug, a fibrin clot. The IIb / IIIa complex is a major platelet membrane component. There are as many as...
activator in vivo. Platelet polyphosphate-driven factor XII activation provides the link from primary hemostasis (formation of a plateletplug) to secondary...
PMID 12395148. S2CID 24992893. Tsai HM (March 2003). "Platelet activation and the formation of the plateletplug: deficiency of ADAMTS13 causes thrombotic thrombocytopenic...
leading to platelet secretion, recruitment of additional platelets, and aggregation. In physiologic conditions, the resulting plateletplug is the initial...
There are two components to a thrombus: aggregated platelets and red blood cells that form a plug, and a mesh of cross-linked fibrin protein. The substance...
infarction, platelets stick to the damaged lining of the vessel and to each other within seconds and form a plug. These "Sticky platelets" secrete several...
platelets and the coagulation system. Platelets are small blood components that form a plug in the blood vessel wall that stops bleeding. Platelets also...
are specialized secretory organelles. Dense granules are found only in platelets and are smaller than alpha granules. The origin of these dense granules...
reactions from medications such as warfarin, straining, asphyxiation, platelet disorders and diseases such as cytomegalovirus); and purpura (3–10 mm (0...
labeled on blood smears as platelets. The most accurate form of confirming platelet counts is by using a manual platelet count and a review of a peripheral...
referred to as "Whole Blood". Platelets are very small cells. They work with the clotting factors in plasma to form a mesh "plug" to stop or prevent bleeding...
which forms a mesh and acts as "glue" to bind platelets to each other. This makes a clot that serves to plug the break in the blood vessel, slowing/preventing...
in the plasma release-cell layer or sheath flow thickness Many of the platelet-derived substances, including serotonin, are vasodilatory when the endothelium...
an abnormally low number of platelets in the blood, according to recent studies in Denmark and the United States. Platelets, or thrombocytes, are disk-shaped...
Frozen plasma, vitamin K, protamine, or platelet transfusions may be given in case of a coagulopathy. Platelets however appear to worsen outcomes in those...
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