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Rhoptry information


Tachyzoites of Toxoplasma gondii, transmission electron microscopy.[1] Rhoptries: ro (click to enlarge)

A rhoptry is a specialized secretory organelle. They are club-shaped organelles connected by thin necks to the extreme apical pole of the parasite. These organelles, like micronemes, are characteristic of the motile stages of Apicomplexa protozoans. They can vary in number and shape and contain numerous enzymes that are released during the process of host penetration. The proteins they contain are important in the interaction between the host and the parasite, including the formation of the parasitophorous vacuole (PV).[2][3]

  1. ^ Rigoulet, Jacques; Hennache, Alain; Lagourette, Pierre; George, Catherine; Longeart, Loïc; Le Net, Jean-Loïc; Dubey, Jitender P. (2014). "Toxoplasmosis in a bar-shouldered dove (Geopelia humeralis) from the Zoo of Clères, France". Parasite. 21: 62. doi:10.1051/parasite/2014062. ISSN 1776-1042. PMC 4236686. PMID 25407506.
  2. ^ Bradley, Peter J; Chris Ward; Stephen J. Cheng; David L. Alexander; Susan Coller; Graham H. Coombs; Joe Dan Dunn; David J. Ferguson; Sanya J. Sanderson; Jonathan M. Wastling; John C. Boothroyd (October 7, 2005). "Proteomic Analysis of Rhoptry Organelles Reveals Many Novel Constituents for Host-Parasite Interactions in Toxoplasma gondii". J. Biol. Chem. 280 (40): 34245–34258. doi:10.1074/jbc.M504158200. PMID 16002398.
  3. ^ Richard, D; et al. (March 2009). "Identification of rhoptry trafficking determinants and evidence for a novel sorting mechanism in the malaria parasite Plasmodium falciparum". PLOS Pathogens. 5 (3): e1000328. doi:10.1371/journal.ppat.1000328. PMC 2648313. PMID 19266084.

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Rhoptry

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A rhoptry is a specialized secretory organelle. They are club-shaped organelles connected by thin necks to the extreme apical pole of the parasite. These...

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Parasitophorous vacuole

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separate bubble of cytoplasm-filled plasma membrane within the host cell. The rhoptry and the microneme, special secretory organelles found in apicomplexan parasites...

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Microneme

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organelle, the rhoptry, which also is a secretory organelle. It is possible that, while the microneme initiates erythrocyte-binding, the rhoptry secretes proteins...

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Apicomplexan life cycle

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typical, generalised apicomplexan: 1-polar ring, 2-conoid, 3-micronemes, 4-rhoptries, 5-nucleus, 6-nucleolus, 7-mitochondria, 8-posterior ring, 9-alveoli,...

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Plasmodium

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bulbous rhoptries which contain parasite proteins involved in invading the host cell and modifying the host once inside. Adjacent to the rhoptries are smaller...

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Apicomplexa

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of spirally arranged microtubules (the conoid), a secretory body (the rhoptry) and one or more polar rings. Additional slender electron-dense secretory...

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Marta Tufet

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her doctoral degree, where she specialised in parasitology and studied rhoptry proteins. In 2006, Tufet earned a PhD in cellular and molecular biology...

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Eimeria

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host cell membranes. In E. tenella, this involves parasite micronemes and rhoptry proteins including RON2, RON5 and AMA-2. It is unlikely that the host cell...

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Plasmodium falciparum

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organelles, is an important structure. It contains secretory organelles called rhoptries and micronemes, which are vital for mobility, adhesion, host cell invasion...

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Microbial cyst

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Alveoli Trichocyst Dinoflagellates: Dinokaryon Dinocyst Theca Ciliates: Cilium Cirrus Macronucleus Micronucleus Apicomplexans: Rhoptry Apicoplast Microneme...

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Toxoplasmosis

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invading the cell, the parasite releases ROP proteins from the bulb of the rhoptry organelle. These proteins translocate to the nucleus and the surface of...

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Plasmodium malariae

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characteristics of this organism in comparison to general eukaryotes include the rhoptry, micronemes, and polar rings near the apical end. Plasmodium is known best...

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Toxoplasma gondii

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Ethiopia, at 64.2%, as of 2018. T. gondii contains organelles called rhoptries and micronemes, as well as other organelles. The life cycle of T. gondii...

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Chrompodellid

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biflagellated single cells, 5–20 μm in length, with an open conoid and rhoptries used to hunt. They present genetic sequences of non-photosynthetic plastids...

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Malaria prophylaxis

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(RHs) are both used by specialized P. falciparum organelles known as rhoptries and micronemes to bind with the host cell. Disrupting the binding process...

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Alveolate

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myzocytotic predator with two heterodynamic flagella, micropores, trichocysts, rhoptries, micronemes, a polar ring and a coiled open sided conoid. While the common...

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Hydrogenosome

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Alveoli Trichocyst Dinoflagellates: Dinokaryon Dinocyst Theca Ciliates: Cilium Cirrus Macronucleus Micronucleus Apicomplexans: Rhoptry Apicoplast Microneme...

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Plasmodium knowlesi

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specialized for invading host cells. These include the large bulbous rhoptries, smaller micronemes, and dispersed dense granules, each of which secretes...

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Mitosome

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Alveoli Trichocyst Dinoflagellates: Dinokaryon Dinocyst Theca Ciliates: Cilium Cirrus Macronucleus Micronucleus Apicomplexans: Rhoptry Apicoplast Microneme...

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Anthemosoma

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described in 1969 by Landau, Boulard and Housin. Although polar rings and rhoptries are present other typical Apicomplexian features including conoid, flagellae...

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Theileria parva

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ISSN 2165-8102. PMID 25422856. "Theileria parva microneme-rhoptry antigen (p104 gene)" (PDF). Techne. Morrison, W. Ivan. "Theileriases"....

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Cardiosporidium

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the host. Like other members of this phylum it possesses apicoplasts, rhoptry and subpellicular microtubules. This Apicomplexan parasite is occasionally...

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IRGs

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demonstrates a co-evolving interaction between the two species. Type I T. gondii rhoptry effector molecule Rop18, a serine-threonine kinase, was recently shown...

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Ferlins

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of the Ferlin Calcium Sensor Family Is Essential for Toxoplasma gondii Rhoptry Secretion". mBio. 9 (5). doi:10.1128/mBio.01510-18. PMC 6168857. PMID 30279285...

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Aconoidasida

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of their outer membrane. This apical complex includes vesicles called rhoptries and micronemes, which open at the anterior of the cell. These secrete...

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Acrocoelus

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structurally complex. These may be extrusomes. The types II and III appear to be rhoptry and microneme like organelles respectively. The type species is Acrocoelus...

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Hammondia hammondi

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two consistent differences between their tachyzoites and sporozoites. Rhoptries in H. hammondi tachyzoites are electron-dense whereas those of T. gondii...

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Deepak Gaur

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Virander Singh Chauhan; Deepak Gaur (2016). "A novel Plasmodium falciparum rhoptry associated adhesin mediates erythrocyte invasion through the sialic-acid...

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Goussia

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cells made of fibers, which are currently unknown, that surround the rhoptries. The conoid is thought to have a mechanical function and assist in the...

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