positive regulation of endothelial cell proliferation
ossification
regulation of bone mineralization
regulation of transcription by RNA polymerase II
biomineral tissue development
negative regulation of cytokine-mediated signaling pathway
positive regulation of angiogenesis
angiogenesis
positive regulation of I-kappaB kinase/NF-kappaB signaling
inflammatory response
regulation of type 2 immune response
platelet degranulation
signal transduction
Sources:Amigo / QuickGO
Orthologs
Species
Human
Mouse
Entrez
1893
13601
Ensembl
ENSG00000143369
ENSMUSG00000028108
UniProt
Q16610
Q61508
RefSeq (mRNA)
NM_022664 NM_001202858 NM_004425
NM_001252653 NM_007899 NM_001355070
RefSeq (protein)
NP_001189787 NP_004416 NP_073155
NP_001239582 NP_031925 NP_001341999
Location (UCSC)
Chr 1: 150.51 – 150.51 Mb
Chr 3: 95.64 – 95.65 Mb
PubMed search
[3]
[4]
Wikidata
View/Edit Human
View/Edit Mouse
Extracellular matrix protein 1 is a protein that in humans is encoded by the ECM1 gene.[5][6][7]
This gene encodes an extracellular protein containing motifs with a cysteine pattern characteristic of the cysteine pattern of the ligand-binding "double-loop" domains of the albumin protein family. This gene maps outside the epidermal differentiation complex (EDC), a cluster of three gene families involved in epidermal differentiation. Alternatively spliced transcript variants encoding distinct isoforms have been described.[7]
^ abcGRCh38: Ensembl release 89: ENSG00000143369 – Ensembl, May 2017
^ abcGRCm38: Ensembl release 89: ENSMUSG00000028108 – Ensembl, May 2017
^"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^Smits P, Ni J, Feng P, Wauters J, Van Hul W, Boutaibi ME, Dillon PJ, Merregaert J (Jan 1998). "The human extracellular matrix gene 1 (ECM1): genomic structure, cDNA cloning, expression pattern, and chromosomal localization". Genomics. 45 (3): 487–95. doi:10.1006/geno.1997.4918. PMID 9367673.
^Johnson MR, Wilkin DJ, Vos HL, Ortiz de Luna RI, Dehejia AM, Polymeropoulos MH, Francomano CA (May 1998). "Characterization of the human extracellular matrix protein 1 gene on chromosome 1q21". Matrix Biol. 16 (5): 289–92. doi:10.1016/S0945-053X(97)90017-2. PMID 9501329.
^ ab"Entrez Gene: ECM1 extracellular matrix protein 1".
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Global Information
